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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:40.1 nTPM
HPA Brain:72.5 nTPM
GTEx:40.1 nTPM
FANTOM5:146.5 Scaled Tags Per Million
Pig:76.2 nTPM
Mouse:106.9 nTPM
Allen mouse:12.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 68.2
2411 Female, age 72, unknown 79.4
2019 Male, age 18, unknown 73.8
2666 Male, age 74, left hemisphere 69.5
1827 Male, age 72, unknown 68.9
2586 Male, age 75, left hemisphere 68.5
2828 Female, age 72, unknown 67.3
1833 Male, age 53, unknown 65.7
1830 Male, age 51, unknown 65.4
1870 Female, age 42, unknown 65.2
2219 Male, age 76, both hemispheres 58.8
Dorsal raphe nucleus
nTPM: 64.2
2750 Male, age 76, both hemispheres 74.6
2047 Male, age 72, unknown 65.4
2298 Female, age 72, unknown 62.7
1828 Male, age 53, unknown 61.9
2016 Female, age 72, unknown 56.4
Inferior colliculus
nTPM: 54.3
1890 Male, age 53, unknown 55.5
1848 Female, age 42, unknown 54.7
2097 Female, age 72, unknown 54.5
2849 Male, age 72, unknown 52.5
Median raphe nucleus
nTPM: 64.8
2220 Male, age 76, midline 64.8
Periaquaductal grey, anterior
nTPM: 62.2
1947 Male, age 18, unknown 68.4
1795 Male, age 51, unknown 59.9
2502 Female, age 75, unknown 58.4
Periaquaductal grey, dorsal
nTPM: 54.3
2464 Female, age 72, unknown 61.1
1840 Male, age 53, unknown 55.1
1831 Male, age 72, unknown 53.9
2850 Male, age 76, both hemispheres 47.0
Periaquaductal grey, lateral
nTPM: 56.3
2272 Male, age 74, both hemispheres 59.7
2053 Male, age 18, unknown 58.5
2140 Male, age 76, both hemispheres 50.7
Pretectal area
nTPM: 66.5
2007 Male, age 72, unknown 79.2
1815 Male, age 53, unknown 73.0
1817 Female, age 42, unknown 72.3
1816 Male, age 51, unknown 71.6
1944 Female, age 72, unknown 67.6
2316 Male, age 76, right hemisphere 65.7
2407 Male, age 75, both hemispheres 65.5
2667 Female, age 75, unknown 63.8
2825 Male, age 18, unknown 59.1
2224 Female, age 72, unknown 57.2
2273 Male, age 74, both hemispheres 56.1
Red nucleus
nTPM: 69.9
2823 Male, age 76, right hemisphere 78.0
2503 Female, age 72, unknown 73.1
1904 Male, age 53, unknown 72.8
2588 Male, age 74, left hemisphere 72.7
2785 Male, age 18, unknown 72.5
1865 Male, age 51, unknown 72.1
1821 Female, age 72, unknown 71.8
2584 Male, age 75, left hemisphere 70.6
2769 Male, age 72, unknown 66.8
1954 Female, age 42, unknown 65.7
2227 Male, age 72, unknown 64.6
2725 Female, age 75, unknown 58.2
Substantia nigra
nTPM: 72.5
1916 Female, age 42, unknown 81.7
1851 Male, age 51, unknown 79.5
2409 Female, age 72, unknown 77.2
2590 Female, age 75, unknown 74.8
2583 Male, age 75, right hemisphere 73.3
2241 Male, age 72, unknown 72.2
1941 Male, age 53, unknown 71.3
1889 Female, age 72, unknown 68.9
2665 Male, age 74, both hemispheres 63.7
2699 Male, age 18, unknown 62.3
Superior colliculus
nTPM: 65.4
2668 Female, age 75, unknown 82.9
1913 Female, age 42, unknown 70.7
1895 Male, age 76, right hemisphere 66.6
2261 Male, age 18, unknown 65.2
2087 Female, age 72, unknown 65.1
1796 Male, age 53, unknown 62.7
2587 Male, age 74, left hemisphere 61.3
1995 Male, age 72, unknown 61.2
1839 Male, age 51, unknown 59.2
2664 Male, age 75, both hemispheres 59.2
Ventral tegmental area
nTPM: 67.2
2410 Female, age 72, unknown 81.0
1915 Female, age 42, unknown 70.8
2218 Male, age 76, both hemispheres 65.1
1942 Male, age 51, unknown 64.4
2021 Male, age 53, unknown 62.7
2223 Female, age 72, unknown 59.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 40.1
Samples: 139

Max nTPM: 60.8
Min nTPM: 24.5
Std nTPM: 7.4
Median nTPM: 39.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 58.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 57.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 57.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 57.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 56.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 53.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 52.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 52.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 50.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 50.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 49.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 49.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 48.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 48.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 48.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 48.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 48.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 47.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 47.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 47.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 47.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 47.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 46.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 46.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 46.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 46.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 46.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 46.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 46.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 45.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 45.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 45.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 44.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 44.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 44.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 44.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 43.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 43.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 43.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 43.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 42.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 42.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 42.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 41.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 41.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 41.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 41.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 41.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 41.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 41.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 41.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 41.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 40.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 40.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 40.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 40.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 40.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 40.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 39.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 39.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 39.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 39.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 39.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 39.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 39.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 39.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 39.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 39.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 38.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 38.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 38.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 38.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 37.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 37.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 37.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 37.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 37.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 37.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 37.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 37.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 37.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 36.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 36.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 36.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 36.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 36.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 36.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 36.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 36.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 36.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 36.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 36.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 35.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 35.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 35.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 35.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 35.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 35.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 35.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 34.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 33.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 33.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 33.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 33.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 33.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 33.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 33.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 33.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 33.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 32.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 32.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 32.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 31.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 31.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 31.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 31.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 31.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 30.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 30.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 30.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 30.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 29.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 29.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 29.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 28.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 28.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 27.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 27.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 25.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

146.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 146.5
FF:10158-103A5 76 years, female 146.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

76.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 74.6
Samples: 4

Max nTPM: 90.6
Min nTPM: 60.6
Sample A Female 90.6
Sample B Female 60.6
Sample C Male 74.7
Sample D Male 72.5
Midbrain
nTPM: 76.2
Samples: 4

Max nTPM: 107.6
Min nTPM: 57.1
Sample A Female 107.6
Sample B Female 68.2
Sample C Male 71.7
Sample D Male 57.1
Periaqueductal gray
nTPM: 57.3
Samples: 3

Max nTPM: 60.9
Min nTPM: 52.2
Sample B Female 58.8
Sample C Male 60.9
Sample D Male 52.2
Superior colliculi
nTPM: 67.1
Samples: 4

Max nTPM: 73.2
Min nTPM: 53.5
Sample A Female 73.2
Sample B Female 53.5
Sample C Male 73.0
Sample D Male 68.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 106.9
Samples: 4

Max nTPM: 110.0
Min nTPM: 102.7
Sample A Male 102.7
Sample B Male 105.3
Sample C Female 109.5
Sample D Female 110.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.0
68633261 Antisense, RP_050125_02_F01, Mouse strain C57BL/6J (56 days, male) 12.0

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