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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:16.5 nTPM
HPA Brain:39.7 nTPM
GTEx:16.5 nTPM
FANTOM5:58.0 Scaled Tags Per Million
Pig:10.8 nTPM
Mouse:12.6 nTPM
Allen mouse:4.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

39.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 37.3
2586 Male, age 75, left hemisphere 40.1
1830 Male, age 51, unknown 39.7
1833 Male, age 53, unknown 39.1
1870 Female, age 42, unknown 37.7
2828 Female, age 72, unknown 37.5
1827 Male, age 72, unknown 36.4
2019 Male, age 18, unknown 36.4
2411 Female, age 72, unknown 35.7
2666 Male, age 74, left hemisphere 35.5
2219 Male, age 76, both hemispheres 34.7
Dorsal raphe nucleus
nTPM: 35.3
2750 Male, age 76, both hemispheres 38.4
2016 Female, age 72, unknown 36.5
2047 Male, age 72, unknown 34.7
1828 Male, age 53, unknown 34.5
2298 Female, age 72, unknown 32.1
Inferior colliculus
nTPM: 35.9
2849 Male, age 72, unknown 38.8
1890 Male, age 53, unknown 36.4
1848 Female, age 42, unknown 36.1
2097 Female, age 72, unknown 32.4
Median raphe nucleus
nTPM: 32.7
2220 Male, age 76, midline 32.7
Periaquaductal grey, anterior
nTPM: 36.8
1795 Male, age 51, unknown 37.3
1947 Male, age 18, unknown 36.8
2502 Female, age 75, unknown 36.4
Periaquaductal grey, dorsal
nTPM: 37.4
2850 Male, age 76, both hemispheres 40.5
1831 Male, age 72, unknown 37.3
1840 Male, age 53, unknown 36.2
2464 Female, age 72, unknown 35.5
Periaquaductal grey, lateral
nTPM: 38.7
2140 Male, age 76, both hemispheres 40.5
2272 Male, age 74, both hemispheres 38.8
2053 Male, age 18, unknown 36.6
Pretectal area
nTPM: 36.2
2316 Male, age 76, right hemisphere 41.8
2407 Male, age 75, both hemispheres 37.8
2825 Male, age 18, unknown 37.6
2273 Male, age 74, both hemispheres 37.1
2667 Female, age 75, unknown 37.1
2224 Female, age 72, unknown 35.6
1815 Male, age 53, unknown 35.5
1817 Female, age 42, unknown 35.5
2007 Male, age 72, unknown 34.1
1816 Male, age 51, unknown 33.1
1944 Female, age 72, unknown 33.1
Red nucleus
nTPM: 39.7
2823 Male, age 76, right hemisphere 42.8
1865 Male, age 51, unknown 42.7
2588 Male, age 74, left hemisphere 41.1
2227 Male, age 72, unknown 40.7
1904 Male, age 53, unknown 40.3
2769 Male, age 72, unknown 39.9
1954 Female, age 42, unknown 39.2
2503 Female, age 72, unknown 38.8
2725 Female, age 75, unknown 38.5
2785 Male, age 18, unknown 38.2
2584 Male, age 75, left hemisphere 38.0
1821 Female, age 72, unknown 36.5
Substantia nigra
nTPM: 35.0
2699 Male, age 18, unknown 39.7
2583 Male, age 75, right hemisphere 37.2
2590 Female, age 75, unknown 36.9
2665 Male, age 74, both hemispheres 36.4
1941 Male, age 53, unknown 35.0
2409 Female, age 72, unknown 34.2
1889 Female, age 72, unknown 33.7
1851 Male, age 51, unknown 33.2
1916 Female, age 42, unknown 31.9
2241 Male, age 72, unknown 31.7
Superior colliculus
nTPM: 37.1
1913 Female, age 42, unknown 41.6
1995 Male, age 72, unknown 40.1
1895 Male, age 76, right hemisphere 39.5
1839 Male, age 51, unknown 37.0
1796 Male, age 53, unknown 36.4
2087 Female, age 72, unknown 35.8
2668 Female, age 75, unknown 35.6
2587 Male, age 74, left hemisphere 35.2
2261 Male, age 18, unknown 35.1
2664 Male, age 75, both hemispheres 34.9
Ventral tegmental area
nTPM: 35.1
2218 Male, age 76, both hemispheres 36.7
2223 Female, age 72, unknown 36.4
2021 Male, age 53, unknown 35.3
1942 Male, age 51, unknown 34.8
2410 Female, age 72, unknown 34.3
1915 Female, age 42, unknown 33.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 16.5
Samples: 139

Max nTPM: 25.3
Min nTPM: 9.8
Std nTPM: 2.9
Median nTPM: 16.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 25.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 24.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 23.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 23.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 22.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 22.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 21.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 21.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 21.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 21.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 20.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 20.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 20.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 20.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 20.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 20.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 20.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 20.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 20.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 20.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 19.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 19.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 19.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 19.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 19.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 18.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 18.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 18.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 18.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 18.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 18.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 18.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 17.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 17.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 17.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 17.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 17.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 17.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 17.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 17.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 17.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 17.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 17.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 17.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 17.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 17.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 17.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 17.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 17.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 17.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 17.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 16.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 16.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 16.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 16.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 16.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 16.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 16.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 16.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 16.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 16.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 16.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 16.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 16.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 16.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 16.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 16.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 16.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 16.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 16.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 16.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 16.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 16.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 16.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 15.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 15.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 15.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 15.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 15.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 15.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 15.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 15.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 15.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 15.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 15.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 15.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 15.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 15.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 15.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 15.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 15.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 14.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 14.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 14.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 14.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 14.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 14.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 14.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 14.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 14.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 14.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 14.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 14.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 14.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 14.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 14.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 14.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 14.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 14.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 14.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 13.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 13.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 13.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 13.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 13.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 13.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 13.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 13.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 12.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 12.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 12.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 12.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 12.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 12.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 12.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 12.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 12.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 12.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 11.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 11.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 10.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 10.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 10.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 9.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

58.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 58.0
FF:10158-103A5 76 years, female 58.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

10.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 10.7
Samples: 4

Max nTPM: 13.9
Min nTPM: 8.3
Sample A Female 8.3
Sample B Female 11.3
Sample C Male 9.4
Sample D Male 13.9
Midbrain
nTPM: 10.3
Samples: 4

Max nTPM: 11.5
Min nTPM: 8.4
Sample A Female 11.5
Sample B Female 8.4
Sample C Male 9.9
Sample D Male 11.5
Periaqueductal gray
nTPM: 9.4
Samples: 3

Max nTPM: 9.7
Min nTPM: 9.0
Sample B Female 9.0
Sample C Male 9.7
Sample D Male 9.5
Superior colliculi
nTPM: 10.1
Samples: 4

Max nTPM: 11.4
Min nTPM: 9.0
Sample A Female 9.0
Sample B Female 10.8
Sample C Male 9.1
Sample D Male 11.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 12.6
Samples: 4

Max nTPM: 13.3
Min nTPM: 12.1
Sample A Male 12.5
Sample B Male 13.3
Sample C Female 12.1
Sample D Female 12.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.7
69262318 Antisense, RP_050303_01_H10, Mouse strain C57BL/6J (56 days, male) 4.7

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