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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:65.2 nTPM
HPA Brain:76.5 nTPM
GTEx:65.2 nTPM
FANTOM5:27.4 Scaled Tags Per Million
Pig:81.0 nTPM
Mouse:48.5 nTPM
Allen mouse:4.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

76.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 50.7
2019 Male, age 18, unknown 75.8
2586 Male, age 75, left hemisphere 73.2
2219 Male, age 76, both hemispheres 65.2
2666 Male, age 74, left hemisphere 49.6
2411 Female, age 72, unknown 47.3
2828 Female, age 72, unknown 43.2
1870 Female, age 42, unknown 39.6
1827 Male, age 72, unknown 39.2
1830 Male, age 51, unknown 37.8
1833 Male, age 53, unknown 36.1
Dorsal raphe nucleus
nTPM: 56.6
2298 Female, age 72, unknown 65.8
2047 Male, age 72, unknown 62.6
2750 Male, age 76, both hemispheres 57.5
1828 Male, age 53, unknown 55.2
2016 Female, age 72, unknown 41.8
Inferior colliculus
nTPM: 31.4
1890 Male, age 53, unknown 34.7
2097 Female, age 72, unknown 32.1
2849 Male, age 72, unknown 30.3
1848 Female, age 42, unknown 28.3
Median raphe nucleus
nTPM: 76.5
2220 Male, age 76, midline 76.5
Periaquaductal grey, anterior
nTPM: 42.1
1795 Male, age 51, unknown 55.2
2502 Female, age 75, unknown 43.1
1947 Male, age 18, unknown 27.9
Periaquaductal grey, dorsal
nTPM: 38.3
1831 Male, age 72, unknown 43.0
1840 Male, age 53, unknown 42.4
2464 Female, age 72, unknown 35.6
2850 Male, age 76, both hemispheres 32.3
Periaquaductal grey, lateral
nTPM: 32.0
2272 Male, age 74, both hemispheres 33.6
2140 Male, age 76, both hemispheres 32.5
2053 Male, age 18, unknown 29.9
Pretectal area
nTPM: 48.9
1817 Female, age 42, unknown 78.9
2007 Male, age 72, unknown 69.5
1815 Male, age 53, unknown 57.1
1944 Female, age 72, unknown 52.8
2224 Female, age 72, unknown 50.5
1816 Male, age 51, unknown 48.3
2667 Female, age 75, unknown 40.2
2407 Male, age 75, both hemispheres 39.1
2825 Male, age 18, unknown 38.5
2273 Male, age 74, both hemispheres 32.2
2316 Male, age 76, right hemisphere 30.7
Red nucleus
nTPM: 38.3
2785 Male, age 18, unknown 65.3
2584 Male, age 75, left hemisphere 54.9
2588 Male, age 74, left hemisphere 44.0
2725 Female, age 75, unknown 38.7
1821 Female, age 72, unknown 35.5
2769 Male, age 72, unknown 34.7
2503 Female, age 72, unknown 33.8
2227 Male, age 72, unknown 33.6
1904 Male, age 53, unknown 31.9
1865 Male, age 51, unknown 30.1
1954 Female, age 42, unknown 29.3
2823 Male, age 76, right hemisphere 27.5
Substantia nigra
nTPM: 72.4
2665 Male, age 74, both hemispheres 116.6
1851 Male, age 51, unknown 95.2
1916 Female, age 42, unknown 92.4
2699 Male, age 18, unknown 69.8
1941 Male, age 53, unknown 67.9
2241 Male, age 72, unknown 66.1
2409 Female, age 72, unknown 65.7
1889 Female, age 72, unknown 54.4
2583 Male, age 75, right hemisphere 52.7
2590 Female, age 75, unknown 43.4
Superior colliculus
nTPM: 41.7
2668 Female, age 75, unknown 67.6
2664 Male, age 75, both hemispheres 58.1
2087 Female, age 72, unknown 48.8
1796 Male, age 53, unknown 42.4
2587 Male, age 74, left hemisphere 37.1
1839 Male, age 51, unknown 36.0
1995 Male, age 72, unknown 34.1
1913 Female, age 42, unknown 33.8
1895 Male, age 76, right hemisphere 31.8
2261 Male, age 18, unknown 27.4
Ventral tegmental area
nTPM: 61.6
1915 Female, age 42, unknown 71.7
2410 Female, age 72, unknown 67.5
2021 Male, age 53, unknown 62.7
2218 Male, age 76, both hemispheres 60.9
1942 Male, age 51, unknown 56.4
2223 Female, age 72, unknown 50.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

65.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 65.2
Samples: 139

Max nTPM: 163.4
Min nTPM: 20.0
Std nTPM: 28.2
Median nTPM: 63.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 163.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 163.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 153.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 130.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 124.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 124.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 121.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 119.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 102.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 102.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 100.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 99.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 97.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 97.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 95.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 95.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 95.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 95.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 94.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 92.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 91.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 91.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 90.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 88.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 87.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 85.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 85.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 85.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 83.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 82.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 82.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 82.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 81.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 81.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 81.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 81.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 79.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 78.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 78.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 78.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 78.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 76.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 76.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 75.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 74.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 74.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 73.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 72.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 71.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 71.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 71.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 71.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 71.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 71.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 70.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 70.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 69.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 69.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 68.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 66.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 66.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 65.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 65.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 65.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 64.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 63.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 63.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 63.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 62.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 61.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 61.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 60.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 59.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 58.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 58.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 56.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 55.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 54.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 53.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 52.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 52.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 52.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 51.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 51.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 50.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 50.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 49.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 49.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 48.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 47.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 47.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 46.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 46.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 45.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 44.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 44.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 44.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 44.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 43.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 43.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 42.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 41.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 41.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 41.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 40.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 40.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 39.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 39.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 39.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 39.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 38.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 38.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 38.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 37.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 36.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 35.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 35.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 34.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 34.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 33.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 32.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 30.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 30.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 30.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 29.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 29.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 28.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 27.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 27.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 26.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 26.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 20.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 20.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

27.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 27.4
FF:10158-103A5 76 years, female 27.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

81.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 75.4
Samples: 4

Max nTPM: 100.2
Min nTPM: 52.1
Sample A Female 100.2
Sample B Female 70.8
Sample C Male 78.3
Sample D Male 52.1
Midbrain
nTPM: 74.0
Samples: 4

Max nTPM: 84.6
Min nTPM: 63.9
Sample A Female 82.1
Sample B Female 63.9
Sample C Male 84.6
Sample D Male 65.3
Periaqueductal gray
nTPM: 59.8
Samples: 3

Max nTPM: 71.3
Min nTPM: 51.1
Sample B Female 57.1
Sample C Male 71.3
Sample D Male 51.1
Superior colliculi
nTPM: 81.0
Samples: 4

Max nTPM: 95.9
Min nTPM: 67.2
Sample A Female 91.8
Sample B Female 69.0
Sample C Male 95.9
Sample D Male 67.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

48.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 48.5
Samples: 4

Max nTPM: 52.1
Min nTPM: 45.7
Sample A Male 52.1
Sample B Male 45.7
Sample C Female 46.9
Sample D Female 49.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.3
76081925 Antisense, RP_060626_01_A05, Mouse strain C57BL/6J (56 days, male) 6.8
324211 Antisense, RP_040617_01_E06, Mouse strain C57BL/6J (56 days, male) 6.0
70795448 Antisense, RP_050712_01_F02, Mouse strain C57BL/6J (56 days, male) 0.0

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