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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:57.5 nTPM
HPA Brain:46.8 nTPM
GTEx:57.5 nTPM
FANTOM5:15.8 Scaled Tags Per Million
Pig:32.0 nTPM
Mouse:52.0 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.1
2586 Male, age 75, left hemisphere 58.8
1827 Male, age 72, unknown 47.1
2828 Female, age 72, unknown 45.8
2666 Male, age 74, left hemisphere 45.3
2019 Male, age 18, unknown 44.5
1870 Female, age 42, unknown 42.2
2411 Female, age 72, unknown 40.3
1833 Male, age 53, unknown 37.9
1830 Male, age 51, unknown 36.5
2219 Male, age 76, both hemispheres 32.9
Dorsal raphe nucleus
nTPM: 44.4
2298 Female, age 72, unknown 49.1
2047 Male, age 72, unknown 48.8
1828 Male, age 53, unknown 44.1
2750 Male, age 76, both hemispheres 40.9
2016 Female, age 72, unknown 39.3
Inferior colliculus
nTPM: 43.1
2849 Male, age 72, unknown 43.9
2097 Female, age 72, unknown 43.5
1890 Male, age 53, unknown 42.6
1848 Female, age 42, unknown 42.4
Median raphe nucleus
nTPM: 42.2
2220 Male, age 76, midline 42.2
Periaquaductal grey, anterior
nTPM: 46.8
1947 Male, age 18, unknown 50.2
1795 Male, age 51, unknown 47.2
2502 Female, age 75, unknown 43.1
Periaquaductal grey, dorsal
nTPM: 43.7
1840 Male, age 53, unknown 49.7
2850 Male, age 76, both hemispheres 45.5
1831 Male, age 72, unknown 41.2
2464 Female, age 72, unknown 38.4
Periaquaductal grey, lateral
nTPM: 40.1
2140 Male, age 76, both hemispheres 41.5
2053 Male, age 18, unknown 41.4
2272 Male, age 74, both hemispheres 37.4
Pretectal area
nTPM: 44.3
1817 Female, age 42, unknown 52.6
1816 Male, age 51, unknown 52.0
2007 Male, age 72, unknown 49.8
1944 Female, age 72, unknown 48.9
1815 Male, age 53, unknown 44.7
2667 Female, age 75, unknown 42.8
2825 Male, age 18, unknown 42.0
2407 Male, age 75, both hemispheres 41.5
2224 Female, age 72, unknown 40.4
2273 Male, age 74, both hemispheres 40.4
2316 Male, age 76, right hemisphere 32.5
Red nucleus
nTPM: 39.0
2584 Male, age 75, left hemisphere 48.6
1821 Female, age 72, unknown 43.2
2588 Male, age 74, left hemisphere 41.9
2725 Female, age 75, unknown 41.0
2785 Male, age 18, unknown 40.6
1865 Male, age 51, unknown 39.8
1954 Female, age 42, unknown 37.8
2769 Male, age 72, unknown 37.3
2227 Male, age 72, unknown 35.9
1904 Male, age 53, unknown 35.4
2823 Male, age 76, right hemisphere 33.9
2503 Female, age 72, unknown 33.1
Substantia nigra
nTPM: 46.5
1889 Female, age 72, unknown 49.9
1916 Female, age 42, unknown 49.8
1941 Male, age 53, unknown 49.8
2583 Male, age 75, right hemisphere 49.2
2665 Male, age 74, both hemispheres 47.8
1851 Male, age 51, unknown 46.4
2409 Female, age 72, unknown 46.2
2241 Male, age 72, unknown 43.7
2590 Female, age 75, unknown 42.9
2699 Male, age 18, unknown 39.3
Superior colliculus
nTPM: 42.5
2664 Male, age 75, both hemispheres 51.7
2668 Female, age 75, unknown 48.2
1796 Male, age 53, unknown 44.3
2261 Male, age 18, unknown 43.0
2087 Female, age 72, unknown 42.7
1839 Male, age 51, unknown 42.3
2587 Male, age 74, left hemisphere 40.4
1895 Male, age 76, right hemisphere 38.3
1995 Male, age 72, unknown 37.8
1913 Female, age 42, unknown 36.1
Ventral tegmental area
nTPM: 41.7
2410 Female, age 72, unknown 46.9
1915 Female, age 42, unknown 46.3
2218 Male, age 76, both hemispheres 41.5
1942 Male, age 51, unknown 39.7
2021 Male, age 53, unknown 39.6
2223 Female, age 72, unknown 36.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 57.5
Samples: 139

Max nTPM: 129.1
Min nTPM: 31.2
Std nTPM: 13.4
Median nTPM: 54.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 129.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 108.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 92.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 87.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 85.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 85.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 83.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 81.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 79.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 77.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 75.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 75.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 72.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 69.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 69.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 69.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 68.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 68.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 68.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 68.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 67.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 67.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 66.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 65.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 65.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 65.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 65.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 65.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 65.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 65.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 64.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 64.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 64.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 64.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 64.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 63.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 63.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 63.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 61.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 61.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 61.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 61.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 60.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 59.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 59.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 59.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 59.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 58.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 58.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 58.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 57.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 57.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 57.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 57.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 57.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 56.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 56.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 56.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 56.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 56.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 56.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 55.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 55.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 55.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 54.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 54.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 54.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 54.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 54.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 54.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 54.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 53.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 53.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 53.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 53.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 52.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 52.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 51.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 51.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 51.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 51.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 51.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 51.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 50.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 50.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 50.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 50.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 50.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 50.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 50.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 49.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 49.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 49.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 49.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 49.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 49.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 48.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 48.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 48.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 48.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 48.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 48.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 48.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 47.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 47.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 47.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 47.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 46.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 46.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 45.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 45.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 45.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 44.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 44.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 44.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 44.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 44.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 44.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 43.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 41.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 40.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 40.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 40.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 40.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 38.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 38.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 36.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 32.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 31.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

15.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 15.8
FF:10158-103A5 76 years, female 15.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 32.0
Samples: 4

Max nTPM: 33.3
Min nTPM: 29.5
Sample A Female 33.3
Sample B Female 29.5
Sample C Male 32.4
Sample D Male 32.8
Midbrain
nTPM: 30.4
Samples: 4

Max nTPM: 37.5
Min nTPM: 26.0
Sample A Female 37.5
Sample B Female 30.0
Sample C Male 27.9
Sample D Male 26.0
Periaqueductal gray
nTPM: 29.3
Samples: 3

Max nTPM: 32.0
Min nTPM: 27.9
Sample B Female 27.9
Sample C Male 32.0
Sample D Male 27.9
Superior colliculi
nTPM: 28.8
Samples: 4

Max nTPM: 30.7
Min nTPM: 26.7
Sample A Female 28.1
Sample B Female 26.7
Sample C Male 29.6
Sample D Male 30.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 52.1
Samples: 4

Max nTPM: 55.5
Min nTPM: 48.1
Sample A Male 53.4
Sample B Male 51.3
Sample C Female 48.1
Sample D Female 55.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
678686 Antisense, RP_040914_02_D05, Mouse strain C57BL/6J (56 days, male) 0.7

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