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  • WFDC2
CANCER OVARIAN CANCER Show tissue menu
BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
OV TCGA OV VALIDATION PROTEIN OV CPTAC PROTEIN EXPRESSION
ANTIBODIES
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VALIDATION
Dictionary
Ovarian cancer
Human cancer
Ovary serous cystadenocarcinoma
OVARY SEROUS CYSTADENOCARCINOMA (TCGA) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

WFDC2 is not prognostic in Ovary Serous Cystadenocarcinoma (TCGA)


Stage:

Survival analysis
Current cut offi

Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

:
Best expression cut offi

Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

: 5377.41
Median expressioni

Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

: N/A
Median follow up timei

Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

: N/A
P scorei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

N/A
5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
TCGA RNA samplesi

RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average pTPM 4331.7
Number of samples 349
Samples
Sample Description pTPM
TCGA-23-1107-01A 59 years, female, white, stage:Stage IV, dead, 9 days 26298.1
TCGA-13-0911-01A 55 years, female, white, stage:Stage IV, dead, 1355 days 25109.7
TCGA-04-1648-01A 57 years, female, white, stage:Stage IIIC, dead, 871 days 20322.6
TCGA-24-1544-01A 71 years, female, black or african american, stage:Stage IIIC, dead, 820 days 19480.3
TCGA-20-0987-01A 61 years, female, white, stage:Stage IIIC, dead, 701 days 18925.7
TCGA-13-0923-01A 74 years, female, white, stage:Stage IIIC, alive, 2547 days 18473.0
TCGA-13-0725-01A 44 years, female, white, stage:Stage IIIC, dead, 377 days 16598.6
TCGA-13-0727-01A 71 years, female, white, stage:Stage IIIC, dead, 462 days 15376.8
TCGA-25-2398-01A 71 years, female, white, stage:Stage IIIC, dead, 1369 days 14562.2
TCGA-13-0762-01A 65 years, female, white, stage:Stage IIIC, alive, 3400 days 14214.6
TCGA-13-0887-01A 42 years, female, white, stage:Stage IIIC, dead, 2028 days 13592.6
TCGA-10-0938-01A 80 years, female, white, stage:Stage IIIC, dead, 636 days 13075.0
TCGA-61-1738-01A 60 years, female, black or african american, stage:Stage IIIC, dead, 1089 days 12960.4
TCGA-25-1870-01A 59 years, female, white, stage:Stage IIIC, dead, 455 days 12711.8
TCGA-31-1944-01A 47 years, female, white, stage:Stage IIIC, alive, 1386 days 12518.0
TCGA-61-2101-01A 55 years, female, white, stage:Stage IIIC, dead, 1688 days 12167.5
TCGA-13-0891-01A 73 years, female, white, stage:Stage IV, dead, 3128 days 12155.0
TCGA-24-1103-01A 50 years, female, black or african american, stage:Stage IIIC, dead, 1646 days 12038.7
TCGA-29-1696-01A 43 years, female, white, stage:Stage IIIC, dead, 1032 days 11663.7
TCGA-25-1323-01A 72 years, female, white, stage:Stage IIIC, dead, 395 days 11452.6
TCGA-13-1495-01A 60 years, female, white, stage:Stage IIIC, dead, 2749 days 11166.5
TCGA-24-1469-01A 71 years, female, white, stage:Stage IIIC, alive, 277 days 10871.5
TCGA-29-1688-01A 39 years, female, white, stage:Stage IIIC, dead, 2400 days 10727.5
TCGA-61-2097-01A 71 years, female, white, stage:Stage IIC, alive, 1844 days 10600.2
TCGA-13-1410-01A 57 years, female, white, stage:Stage IV, alive, 2464 days 10397.7
TCGA-23-1022-01A 67 years, female, white, stage:Stage IIIC, dead, 1511 days 10381.0
TCGA-61-2012-01A 81 years, female, white, stage:Stage IIC, alive, 932 days 10298.3
TCGA-30-1718-01A 44 years, female, white, stage:Stage IIIC, dead, 1579 days 9960.9
TCGA-57-1584-01A 47 years, female, white, stage:Stage IIIC, alive, 643 days 9902.4
TCGA-13-0730-01A 71 years, female, white, stage:Stage IIIC, dead, 542 days 9780.4
TCGA-10-0927-01A 65 years, female, stage:Stage IIIC, dead, 2490 days 9768.5
TCGA-13-1507-01A 77 years, female, white, stage:Stage IIIC, dead, 1993 days 9450.4
TCGA-04-1343-01A 72 years, female, white, stage:Stage IV, dead, 361 days 9362.7
TCGA-09-2051-01A 42 years, female, white, stage:Stage IIIC, alive, 1919 days 9349.3
TCGA-24-1551-01A 53 years, female, white, stage:Stage IIIC, dead, 1579 days 9261.5
TCGA-25-1312-01A 69 years, female, white, stage:Stage IV, dead, 31 days 9228.6
TCGA-13-0765-01A 50 years, female, white, stage:Stage IIIC, dead, 1389 days 9016.4
TCGA-25-1329-01A 76 years, female, white, stage:Stage IIIC, dead, 457 days 8892.0
TCGA-13-1506-01A 45 years, female, white, stage:Stage IIIC, dead, 1039 days 8841.6
TCGA-29-1711-01A 45 years, female, black or african american, stage:Stage IIIC, alive, 1053 days 8537.6
TCGA-13-1403-01A 48 years, female, white, stage:Stage IIIC, dead, 2345 days 8456.6
TCGA-09-0366-01A 55 years, female, white, stage:Stage IIIC, dead, 1757 days 8405.3
TCGA-24-2297-01A 56 years, female, white, stage:Stage IIIC, dead, 1699 days 8162.7
TCGA-24-1930-01A 53 years, female, white, stage:Stage IIIC, dead, 2467 days 8121.4
TCGA-13-0924-01A 45 years, female, white, stage:Stage IV, alive, 2614 days 8091.3
TCGA-04-1542-01A 52 years, female, white, stage:Stage IIIB, dead, 2561 days 7786.6
TCGA-24-1560-01A 51 years, female, white, stage:Stage IIIC, dead, 1341 days 7699.5
TCGA-24-1104-01A 56 years, female, white, stage:Stage IV, dead, 1933 days 7610.8
TCGA-13-A5FT-01A 67 years, female, black or african american, stage:Stage IIIC, alive, 2143 days 7574.8
TCGA-24-1416-01A 34 years, female, white, stage:Stage IV, alive, 194 days 7461.7
TCGA-13-0766-01A 42 years, female, white, stage:Stage IIIC, dead, 1725 days 7424.0
TCGA-29-1766-01A 74 years, female, white, stage:Stage IIIC, dead, 1199 days 7369.7
TCGA-04-1341-01A 85 years, female, white, stage:'--, alive, 33 days 7349.3
TCGA-25-1631-01A 73 years, female, white, stage:Stage IIIC, dead, 9 days 7267.0
TCGA-29-1703-01A 56 years, female, black or african american, stage:Stage IIIC, dead, 1815 days 7214.8
TCGA-31-1946-01A 30 years, female, stage:Stage IIIC, alive, 918 days 7175.7
TCGA-10-0937-01A 44 years, female, white, stage:Stage IIIC, dead, 608 days 7108.3
TCGA-25-1635-01A 71 years, female, white, stage:Stage IIIC, dead, 1583 days 6890.7
TCGA-20-1686-01A 75 years, female, white, stage:Stage IIIC, alive, 89 days 6866.7
TCGA-29-1701-01A 56 years, female, white, stage:Stage IIIC, dead, 515 days 6854.5
TCGA-24-1924-01A 65 years, female, white, stage:Stage IIIC, dead, 919 days 6823.7
TCGA-24-1430-01A 68 years, female, white, stage:Stage IIIC, dead, 863 days 6774.7
TCGA-30-1857-01A 64 years, female, white, stage:Stage IV, dead, 8 days 6728.9
TCGA-30-1866-01A 61 years, female, white, stage:Stage IV, dead, 1114 days 6715.1
TCGA-24-2023-01A 54 years, female, white, stage:Stage IIIA, dead, 1364 days 6589.8
TCGA-04-1651-01A 53 years, female, white, stage:Stage IIIC, dead, 1102 days 6512.2
TCGA-29-1761-01A 80 years, female, asian, stage:Stage IIIC, dead, 528 days 6456.0
TCGA-57-1583-01A 57 years, female, black or african american, stage:Stage IIIC, dead, 346 days 6442.5
TCGA-13-1405-01A 49 years, female, white, stage:Stage IV, dead, 868 days 6351.8
TCGA-10-0931-01A 44 years, female, white, stage:Stage IIIC, dead, 1000 days 6304.6
TCGA-57-1586-01A 66 years, female, white, stage:Stage IIIC, alive, 679 days 6288.3
TCGA-04-1331-01A 78 years, female, white, stage:Stage IIIC, dead, 1336 days 6286.9
TCGA-31-1950-01A 76 years, female, white, stage:Stage IIIC, alive, 571 days 6227.9
TCGA-29-1784-01A 55 years, female, white, stage:Stage IIIC, alive, 163 days 6079.4
TCGA-59-2350-01A 44 years, female, stage:Stage IV, dead, 679 days 6064.4
TCGA-09-2045-01A 50 years, female, asian, stage:Stage IV, dead, 1069 days 5924.6
TCGA-04-1519-01A 48 years, female, stage:Stage IIIC, alive, 24 days 5897.9
TCGA-25-1322-01A 62 years, female, white, stage:Stage IV, dead, 91 days 5743.8
TCGA-23-1110-01A 42 years, female, white, stage:Stage IIIC, alive, 1658 days 5646.5
TCGA-24-1423-01A 61 years, female, white, stage:Stage IIIC, alive, 190 days 5632.0
TCGA-13-0795-01A 66 years, female, white, stage:Stage IIIC, dead, 619 days 5628.0
TCGA-29-1783-01A 58 years, female, white, stage:Stage IIIC, alive, 220 days 5615.1
TCGA-29-A5NZ-01A 66 years, female, black or african american, stage:Stage IIIC, dead, 1088 days 5599.7
TCGA-24-1424-01A 67 years, female, white, stage:Stage IIIC, alive, 183 days 5586.7
TCGA-23-1027-01A 48 years, female, white, stage:Stage IIIC, dead, 976 days 5552.0
TCGA-24-1546-01A 46 years, female, white, stage:Stage IIIC, dead, 1955 days 5551.5
TCGA-13-0724-01A 72 years, female, white, stage:Stage IV, dead, 83 days 5493.7
TCGA-04-1356-01A 62 years, female, white, stage:Stage IIC, dead, 1499 days 5378.6
TCGA-23-1028-01A 43 years, female, white, stage:Stage IIIC, alive, 1503 days 5376.2
TCGA-04-1347-01A 81 years, female, white, stage:Stage IV, alive, 1919 days 5365.0
TCGA-29-1697-01A 62 years, female, white, stage:Stage IIIC, dead, 949 days 5350.6
TCGA-29-1769-01A 40 years, female, white, stage:Stage IIIC, alive, 699 days 5317.9
TCGA-13-0888-01A 78 years, female, white, stage:Stage IIIC, dead, 2811 days 5292.8
TCGA-29-1694-01A 45 years, female, white, stage:Stage IIIC, dead, 1187 days 5238.9
TCGA-59-2352-01A 78 years, female, white, stage:Stage IIIC, dead, 286 days 5208.7
TCGA-61-1728-01A 59 years, female, white, stage:Stage IV, alive, 848 days 5183.8
TCGA-24-1434-01A 59 years, female, white, stage:Stage IIIC, dead, 568 days 5140.2
TCGA-09-1669-01A 54 years, female, white, stage:Stage IIIA, alive, 928 days 5072.5
TCGA-13-0906-01A 50 years, female, white, stage:Stage IIIC, alive, 3619 days 5033.8
TCGA-25-2396-01A 71 years, female, white, stage:Stage IIIC, dead, 92 days 5026.4
TCGA-04-1332-01A 70 years, female, white, stage:Stage IIIC, dead, 1247 days 4953.8
TCGA-24-1413-01A 51 years, female, white, stage:Stage IIIC, alive, 192 days 4937.0
TCGA-36-1570-01A 49 years, female, white, stage:Stage IIIC, alive, 655 days 4933.3
TCGA-13-1497-01A 47 years, female, white, stage:Stage IIIC, alive, 3871 days 4922.9
TCGA-24-1923-01A 51 years, female, white, stage:Stage IIIC, dead, 690 days 4917.6
TCGA-24-1562-01A 67 years, female, white, stage:Stage IIIC, dead, 1384 days 4879.6
TCGA-13-1498-01A 73 years, female, white, stage:Stage IIIC, dead, 2012 days 4870.3
TCGA-23-1113-01A 48 years, female, white, stage:Stage IV, dead, 949 days 4788.3
TCGA-25-1321-01A 65 years, female, white, stage:Stage IIIC, dead, 1033 days 4777.0
TCGA-13-0886-01A 67 years, female, white, stage:Stage IIIC, alive, 4665 days 4744.8
TCGA-29-1785-01A 55 years, female, white, stage:Stage IIIC, dead, 1104 days 4737.4
TCGA-24-1557-01A 49 years, female, white, stage:Stage IIIC, dead, 1213 days 4722.1
TCGA-24-1616-01A 56 years, female, white, stage:Stage IIIC, dead, 1163 days 4609.4
TCGA-25-2409-01A 71 years, female, white, stage:Stage IV, dead, 821 days 4597.1
TCGA-23-1116-01A 83 years, female, white, stage:Stage IIIC, dead, 592 days 4519.9
TCGA-57-1993-01A 56 years, female, white, stage:Stage IIIC, alive, 763 days 4517.1
TCGA-13-1511-01A 52 years, female, asian, stage:Stage IV, dead, 1650 days 4515.4
TCGA-24-0966-01A 78 years, female, black or african american, stage:Stage IIIC, alive, 232 days 4509.0
TCGA-29-2427-01A 60 years, female, white, stage:Stage IIIC, alive, 1900 days 4437.6
TCGA-25-1315-01A 50 years, female, white, stage:Stage IIIC, dead, 1583 days 4360.6
TCGA-13-1487-01A 74 years, female, white, stage:Stage IV, dead, 681 days 4345.2
TCGA-23-1111-01A 63 years, female, white, stage:Stage IIIC, alive, 98 days 4293.2
TCGA-30-1860-01A 58 years, female, white, stage:Stage IIIC, dead, 1366 days 4254.7
TCGA-61-1724-01A 47 years, female, white, stage:Stage IIIC, dead, 637 days 4244.2
TCGA-24-1418-01A 68 years, female, white, stage:Stage IIIC, alive, 243 days 4237.0
TCGA-25-1626-01A 65 years, female, white, stage:Stage IIIC, dead, 518 days 4224.9
TCGA-29-2428-01A 58 years, female, white, stage:Stage IIIC, alive, 1372 days 4216.9
TCGA-61-2009-01A 65 years, female, white, stage:Stage IIIC, alive, 1212 days 4178.0
TCGA-24-1567-01A 54 years, female, white, stage:Stage IIIB, dead, 524 days 4145.2
TCGA-24-0982-01A 77 years, female, white, stage:Stage IIIC, dead, 679 days 4019.8
TCGA-23-1030-01A 64 years, female, white, stage:Stage IIIC, alive, 886 days 4007.1
TCGA-13-1483-01A 61 years, female, white, stage:Stage IIIC, dead, 895 days 3999.2
TCGA-61-1737-01A 42 years, female, white, stage:Stage IV, alive, 1364 days 3994.4
TCGA-04-1364-01A 61 years, female, white, stage:Stage IIIC, dead, 1024 days 3986.4
TCGA-29-2414-01A 75 years, female, white, stage:Stage IIIC, dead, 2621 days 3966.6
TCGA-24-1431-01A 67 years, female, white, stage:Stage IIIC, dead, 583 days 3965.9
TCGA-23-2077-01A 45 years, female, white, stage:Stage IIIC, alive, 3525 days 3951.1
TCGA-5X-AA5U-01A 61 years, female, black or african american, stage:Stage IIC, alive, 361 days 3947.6
TCGA-24-1844-01A 64 years, female, white, stage:Stage IIIC, alive, 113 days 3893.1
TCGA-13-0714-01A 55 years, female, white, stage:Stage IV, dead, 189 days 3891.8
TCGA-61-2000-01A 67 years, female, white, stage:Stage IIIC, alive, 441 days 3835.7
TCGA-13-1501-01A 50 years, female, white, stage:Stage IV, dead, 1314 days 3809.4
TCGA-13-0720-01A 48 years, female, white, stage:Stage IIIC, dead, 1355 days 3778.9
TCGA-29-1693-01A 72 years, female, white, stage:Stage IIIC, alive, 3096 days 3753.5
TCGA-59-2363-01A 40 years, female, asian, stage:Stage IIIA, alive, 165 days 3750.2
TCGA-29-1776-01A 63 years, female, black or african american, stage:Stage IIIC, alive, 360 days 3748.0
TCGA-61-1900-01A 51 years, female, black or african american, stage:Stage IIIB, alive, 176 days 3720.4
TCGA-61-2003-01A 53 years, female, white, stage:Stage IIIC, alive, 122 days 3695.6
TCGA-13-0804-01A 73 years, female, white, stage:Stage IIIC, dead, 1073 days 3656.0
TCGA-25-1319-01A 73 years, female, white, stage:Stage IIIC, dead, 1977 days 3654.7
TCGA-61-1911-01A 55 years, female, white, stage:Stage IIA, alive, 1293 days 3633.2
TCGA-13-0920-01A 65 years, female, white, stage:Stage IIIC, dead, 1484 days 3619.3
TCGA-61-1919-01A 58 years, female, white, stage:Stage IIIC, dead, 1161 days 3595.5
TCGA-20-1687-01A 46 years, female, white, stage:Stage IV, alive, 81 days 3591.2
TCGA-04-1361-01A 57 years, female, white, stage:Stage IIIB, alive, 989 days 3587.2
TCGA-13-0797-01A 49 years, female, white, stage:Stage IIIC, alive, 2121 days 3582.1
TCGA-29-1763-01A 43 years, female, black or african american, stage:Stage IIC, alive, 2032 days 3555.4
TCGA-25-1318-01A 54 years, female, white, stage:Stage IIIC, dead, 1064 days 3547.0
TCGA-61-1914-01A 65 years, female, stage:Stage IIIC, alive, 1722 days 3513.4
TCGA-24-2293-01A 47 years, female, white, stage:'--, dead, 506 days 3511.4
TCGA-25-1630-01A 73 years, female, white, stage:Stage IIIC, dead, 1162 days 3481.2
TCGA-10-0933-01A 77 years, female, white, stage:Stage IIIC, dead, 446 days 3480.8
TCGA-29-1705-01A 47 years, female, white, stage:Stage IIIC, dead, 555 days 3474.9
TCGA-13-0800-01A 52 years, female, white, stage:Stage IIIC, alive, 2661 days 3450.6
TCGA-24-2281-01A 68 years, female, white, stage:Stage IIA, alive, 1357 days 3441.7
TCGA-36-1574-01A 48 years, female, asian, stage:Stage IIIC, alive, 686 days 3424.8
TCGA-09-1666-01A 57 years, female, white, stage:Stage IIIC, alive, 1752 days 3423.4
TCGA-25-1628-01A 67 years, female, white, stage:Stage IIIC, dead, 627 days 3352.5
TCGA-61-2111-01A 61 years, female, white, stage:Stage IV, alive, 3825 days 3340.0
TCGA-23-1118-01A 45 years, female, white, stage:Stage IIIC, alive, 2616 days 3339.9
TCGA-24-1435-01A 57 years, female, white, stage:Stage IIIC, dead, 1324 days 3334.9
TCGA-36-1576-01A 76 years, female, stage:Stage IIIC, alive, 915 days 3328.4
TCGA-25-1320-01A 65 years, female, white, stage:Stage IIIC, dead, 1155 days 3320.2
TCGA-09-0367-01A 67 years, female, native hawaiian or other pacific islander, stage:Stage IIIC, dead, 547 days 3319.7
TCGA-04-1350-01A 46 years, female, white, stage:Stage IIIC, dead, 1946 days 3302.9
TCGA-23-1123-01A 59 years, female, white, stage:Stage IIIC, dead, 1018 days 3272.7
TCGA-61-1725-01A 40 years, female, white, stage:Stage IIIC, alive, 956 days 3271.4
TCGA-24-1847-01A 45 years, female, white, stage:Stage IV, alive, 343 days 3267.5
TCGA-13-1488-01A 59 years, female, white, stage:Stage IV, dead, 2154 days 3243.9
TCGA-61-1741-01A 76 years, female, white, stage:Stage IIIB, dead, 1024 days 3198.9
TCGA-61-2098-01A 62 years, female, white, stage:Stage IIIC, alive, 1993 days 3196.7
TCGA-13-1496-01A 65 years, female, white, stage:Stage IIIC, dead, 129 days 3174.9
TCGA-04-1365-01A 87 years, female, white, stage:Stage IIIB, alive, 947 days 3161.0
TCGA-36-1581-01A 63 years, female, white, stage:Stage IIC, alive, 751 days 3156.7
TCGA-23-1109-01A 62 years, female, white, stage:Stage IIIC, dead, 1562 days 3148.8
TCGA-24-2280-01A 74 years, female, white, stage:Stage IIIC, alive, 2143 days 3148.1
TCGA-31-1951-01A 58 years, female, white, stage:Stage IIIC, alive, 684 days 3133.4
TCGA-36-1569-01A 52 years, female, white, stage:Stage IIIC, alive, 885 days 3126.3
TCGA-29-2425-01A 60 years, female, white, stage:Stage IIIC, alive, 1977 days 3095.9
TCGA-13-0768-01A 73 years, female, white, stage:Stage IIIC, dead, 1784 days 3080.9
TCGA-25-2400-01A 76 years, female, white, stage:Stage IIIC, dead, 1278 days 3076.2
TCGA-25-1634-01A 75 years, female, white, stage:Stage IIIC, dead, 1091 days 3019.2
TCGA-24-2290-01A 56 years, female, white, stage:Stage IIIC, dead, 1102 days 2993.5
TCGA-57-1994-01A 63 years, female, white, stage:'--, alive, 761 days 2969.1
TCGA-13-1408-01A 59 years, female, white, stage:Stage IIIC, dead, 1680 days 2963.7
TCGA-36-1571-01A 53 years, female, white, stage:Stage IIIB, dead, 695 days 2961.6
TCGA-25-1313-01A 62 years, female, white, stage:Stage IV, dead, 820 days 2958.2
TCGA-23-1119-01A 64 years, female, white, stage:Stage IIIC, alive, 3953 days 2901.2
TCGA-30-1714-01A 68 years, female, white, stage:Stage IV, dead, 1158 days 2887.8
TCGA-36-1580-01A 82 years, female, stage:Stage IIIC, dead, 737 days 2876.9
TCGA-61-1918-01A 45 years, female, white, stage:Stage IV, dead, 479 days 2874.0
TCGA-13-1407-01A 51 years, female, white, stage:Stage IIIC, alive, 2534 days 2866.0
TCGA-24-1850-01A 72 years, female, white, stage:Stage IIIC, alive, 168 days 2850.5
TCGA-04-1514-01A 45 years, female, white, stage:Stage IIIA, dead, 1720 days 2830.9
TCGA-61-2088-01A 51 years, female, white, stage:Stage IIIC, alive, 145 days 2830.1
TCGA-24-2033-01A 87 years, female, white, stage:Stage IIIC, dead, 562 days 2804.4
TCGA-23-2084-01A 45 years, female, white, stage:Stage IV, dead, 1516 days 2802.7
TCGA-25-1623-01A 71 years, female, white, stage:Stage IV, dead, 565 days 2802.4
TCGA-25-1317-01A 66 years, female, white, stage:Stage IIIC, dead, 61 days 2754.7
TCGA-24-1603-01A 53 years, female, white, stage:Stage IIIB, dead, 2742 days 2730.7
TCGA-24-1928-01A 77 years, female, white, stage:Stage IIIC, dead, 336 days 2679.4
TCGA-13-1492-01A 66 years, female, white, stage:Stage IIIC, dead, 3819 days 2669.5
TCGA-24-1553-01A 53 years, female, white, stage:Stage IIIB, dead, 1767 days 2653.2
TCGA-24-0968-01A 59 years, female, white, stage:Stage IIIC, dead, 598 days 2648.9
TCGA-59-2351-01A 51 years, female, white, stage:Stage IIIC, alive, 3532 days 2637.0
TCGA-13-2060-01A 51 years, female, white, stage:Stage IV, alive, 2369 days 2615.0
TCGA-61-2113-01A 53 years, female, white, stage:Stage IIC, dead, 676 days 2579.5
TCGA-30-1862-01A 65 years, female, white, stage:Stage IV, dead, 186 days 2555.4
TCGA-31-1953-01A 52 years, female, asian, stage:Stage IIIC, alive, 204 days 2547.6
TCGA-29-1762-01A 59 years, female, white, stage:Stage IV, dead, 2634 days 2518.2
TCGA-23-2078-01A 66 years, female, white, stage:Stage IIIC, alive, 2661 days 2499.5
TCGA-61-1733-01A 71 years, female, white, stage:Stage IIIC, alive, 967 days 2485.3
TCGA-30-1853-01A 58 years, female, white, stage:Stage IIIC, dead, 1103 days 2450.4
TCGA-24-2298-01A 55 years, female, white, stage:Stage IIIC, dead, 1620 days 2448.5
TCGA-13-1485-01A 48 years, female, white, stage:Stage IV, dead, 629 days 2447.0
TCGA-24-2024-01A 72 years, female, black or african american, stage:Stage IIIC, dead, 1769 days 2438.4
TCGA-24-0979-01A 53 years, female, white, stage:Stage IV, dead, 1264 days 2427.1
TCGA-24-1843-01A 66 years, female, white, stage:Stage IIIC, alive, 106 days 2394.5
TCGA-25-1627-01A 73 years, female, white, stage:Stage IIIC, dead, 394 days 2391.0
TCGA-25-1326-01A 61 years, female, white, stage:Stage IIIC, dead, 1249 days 2371.8
TCGA-23-1023-01A 65 years, female, white, stage:Stage IIIC, alive, 1233 days 2352.9
TCGA-13-0885-01A 70 years, female, white, stage:Stage IIIC, alive, 3388 days 2350.7
TCGA-24-2271-01A 55 years, female, asian, stage:Stage IIIC, dead, 962 days 2338.1
TCGA-24-1565-01A 74 years, female, white, stage:Stage IIIC, dead, 312 days 2322.6
TCGA-23-1122-01A 53 years, female, white, stage:Stage IIIC, dead, 1189 days 2321.7
TCGA-24-1422-01A 82 years, female, black or african american, stage:Stage IIIC, dead, 23 days 2279.4
TCGA-61-1995-01A 43 years, female, white, stage:Stage IIIC, alive, 61 days 2270.6
TCGA-25-2404-01A 38 years, female, american indian or alaska native, stage:Stage IIIC, dead, 883 days 2261.8
TCGA-24-1604-01A 66 years, female, white, stage:Stage IIIC, dead, 2688 days 2236.4
TCGA-24-1105-01A 36 years, female, white, stage:Stage IIIC, dead, 1442 days 2212.7
TCGA-VG-A8LO-01A 55 years, female, black or african american, stage:Stage IV, dead, 24 days 2212.5
TCGA-24-1846-01A 45 years, female, stage:Stage IIIC, alive, 133 days 2180.3
TCGA-23-1809-01A 63 years, female, white, stage:Stage IIC, alive, 16 days 2178.9
TCGA-13-1409-01A 73 years, female, white, stage:Stage IIIC, dead, 1742 days 2166.2
TCGA-24-1426-01A 43 years, female, white, stage:Stage IIIC, alive, 163 days 2160.9
TCGA-61-1998-01A 48 years, female, white, stage:Stage IIIC, alive, 168 days 2149.4
TCGA-31-1959-01A 49 years, female, white, stage:Stage IV, alive, 67 days 2142.0
TCGA-24-2036-01A 50 years, female, white, stage:Stage IIIA, dead, 1947 days 2120.8
TCGA-24-2261-01A 76 years, female, white, stage:Stage IIIC, dead, 24 days 2112.5
TCGA-24-2026-01A 79 years, female, white, stage:Stage IIIC, dead, 1059 days 2096.4
TCGA-30-1892-01A 52 years, female, white, stage:Stage IIIC, dead, 1484 days 2060.7
TCGA-23-1024-01A 52 years, female, white, stage:Stage IV, alive, 468 days 2019.5
TCGA-61-2110-01A 56 years, female, white, stage:Stage IIIC, dead, 1354 days 2000.9
TCGA-29-1695-01A 62 years, female, white, stage:Stage IIIC, dead, 1229 days 1986.4
TCGA-36-1568-01A 52 years, female, stage:Stage IIIC, alive, 875 days 1972.1
TCGA-20-0991-01A 78 years, female, white, stage:Stage IIB, alive, 797 days 1950.8
TCGA-24-1842-01A 49 years, female, white, stage:Stage IIIC, alive, 253 days 1909.2
TCGA-36-1577-01A 43 years, female, asian, stage:Stage IIC, alive, 783 days 1908.3
TCGA-WR-A838-01A 72 years, female, black or african american, stage:Stage IIIC, dead, 304 days 1904.4
TCGA-29-1710-01A 54 years, female, white, stage:Stage IIIC, dead, 951 days 1899.8
TCGA-04-1362-01A 59 years, female, white, stage:Stage IIC, dead, 1348 days 1889.8
TCGA-24-1845-01A 42 years, female, white, stage:Stage IIIC, alive, 116 days 1870.2
TCGA-24-2254-01A 66 years, female, white, stage:Stage IIIC, dead, 1736 days 1836.9
TCGA-20-1682-01A 56 years, female, white, stage:Stage IIIC, alive, 837 days 1820.7
TCGA-09-2054-01A 58 years, female, black or african american, stage:Stage IIIC, dead, 637 days 1814.7
TCGA-04-1536-01A 60 years, female, black or african american, stage:Stage IV, dead, 885 days 1800.7
TCGA-59-2355-01A 58 years, female, white, stage:Stage IV, dead, 65 days 1798.7
TCGA-61-2109-01A 40 years, female, white, stage:Stage IIIC, dead, 629 days 1756.4
TCGA-13-1411-01A 81 years, female, white, stage:Stage IIIC, dead, 531 days 1740.6
TCGA-24-1563-01A 66 years, female, black or african american, stage:Stage IIIC, dead, 1451 days 1725.4
TCGA-13-1512-01A 49 years, female, white, stage:Stage IIIC, alive, 442 days 1705.6
TCGA-57-1585-01A 57 years, female, white, stage:Stage IIIC, dead, 53 days 1688.0
TCGA-24-1467-01A 51 years, female, white, stage:Stage IIIC, dead, 3224 days 1678.8
TCGA-24-2267-01A 58 years, female, white, stage:Stage IIB, dead, 1446 days 1655.1
TCGA-24-1549-01A 58 years, female, white, stage:Stage IIIB, dead, 1721 days 1632.6
TCGA-59-2348-01A 59 years, female, white, stage:Stage IIIC, alive, 5481 days 1597.5
TCGA-04-1655-01A 49 years, female, white, stage:Stage IIIB, dead, 1380 days 1593.8
TCGA-OY-A56Q-01A 78 years, female, black or african american, stage:Stage IIA, alive, 576 days 1587.9
TCGA-29-1690-01A 66 years, female, white, stage:Stage IIIC, dead, 1448 days 1579.7
TCGA-29-1770-01A 54 years, female, white, stage:Stage IIIC, alive, 741 days 1576.7
TCGA-61-1907-01A 63 years, female, white, stage:Stage IIIC, alive, 952 days 1566.3
TCGA-13-1510-01A 62 years, female, white, stage:Stage IIIC, dead, 1359 days 1559.8
TCGA-61-2104-01A 53 years, female, white, stage:Stage IIC, alive, 2338 days 1557.3
TCGA-24-1464-01A 70 years, female, white, stage:Stage IIIC, dead, 379 days 1545.8
TCGA-13-1499-01A 56 years, female, white, stage:Stage IIIC, alive, 3500 days 1491.3
TCGA-24-1427-01A 58 years, female, stage:Stage IIIC, alive, 147 days 1488.0
TCGA-29-1778-01A 77 years, female, white, stage:Stage IIIC, alive, 454 days 1485.5
TCGA-13-0897-01A 54 years, female, white, stage:Stage IIIC, dead, 2182 days 1460.0
TCGA-24-1558-01A 73 years, female, white, stage:Stage IIIC, dead, 594 days 1426.0
TCGA-29-1777-01A 47 years, female, white, stage:Stage IIIC, alive, 374 days 1419.8
TCGA-09-1670-01A 57 years, female, white, stage:Stage IIIA, alive, 547 days 1416.8
TCGA-24-2038-01A 68 years, female, white, stage:Stage IIIA, dead, 1354 days 1408.7
TCGA-24-1428-01A 50 years, female, white, stage:Stage IIIC, alive, 529 days 1393.2
TCGA-09-1662-01A 58 years, female, white, stage:Stage IV, dead, 2717 days 1391.1
TCGA-61-2008-01A 40 years, female, asian, stage:Stage IIC, alive, 932 days 1376.8
TCGA-13-0726-01A 55 years, female, white, stage:Stage IIIC, dead, 949 days 1346.8
TCGA-09-2048-01A 63 years, female, white, stage:Stage IIIC, dead, 138 days 1332.1
TCGA-13-1489-01A 70 years, female, white, stage:Stage IIIC, dead, 2553 days 1317.2
TCGA-25-2401-01A 64 years, female, white, stage:Stage IIIC, dead, 90 days 1304.3
TCGA-13-0916-01A 49 years, female, white, stage:Stage IIIC, alive, 1785 days 1303.9
TCGA-13-0883-01A 61 years, female, white, stage:Stage IIIC, dead, 2097 days 1286.6
TCGA-25-1328-01A 38 years, female, white, stage:Stage IIIC, dead, 2009 days 1260.6
TCGA-25-2399-01A 80 years, female, white, stage:Stage IIIC, dead, 608 days 1256.5
TCGA-13-1477-01A 49 years, female, white, stage:Stage IV, dead, 1662 days 1240.3
TCGA-61-2002-01A 46 years, female, white, stage:Stage IIIC, alive, 547 days 1202.1
TCGA-13-1404-01A 48 years, female, white, stage:Stage IIIC, alive, 2469 days 1197.8
TCGA-29-1768-01A 50 years, female, white, stage:Stage IV, dead, 952 days 1196.8
TCGA-24-1552-01A 77 years, female, white, stage:Stage IIIC, dead, 1259 days 1179.6
TCGA-24-2027-01A 51 years, female, white, stage:Stage IV, dead, 3337 days 1177.6
TCGA-61-1910-01A 56 years, female, white, stage:Stage IIC, alive, 1127 days 1153.8
TCGA-29-1691-01A 51 years, female, white, stage:Stage IIIC, dead, 1470 days 1096.6
TCGA-31-1956-01A 60 years, female, white, stage:Stage IIIB, alive, 1342 days 1080.5
TCGA-25-2392-01A 75 years, female, white, stage:Stage IV, dead, 31 days 1075.7
TCGA-61-2092-01A 57 years, female, white, stage:Stage IIIC, alive, 1573 days 1060.7
TCGA-24-2289-01A 68 years, female, white, stage:Stage IV, dead, 2049 days 1051.2
TCGA-13-1505-01A 63 years, female, white, stage:Stage IIIC, alive, 1998 days 1030.7
TCGA-13-1509-01A 64 years, female, white, stage:Stage IV, alive, 2438 days 1009.4
TCGA-59-2354-01A 63 years, female, white, stage:Stage IIIC, dead, 1046 days 968.6
TCGA-23-1120-01A 60 years, female, white, stage:Stage IIIC, alive, 130 days 958.8
TCGA-24-1417-01A 54 years, female, white, stage:Stage IV, alive, 238 days 827.2
TCGA-25-1316-01A 55 years, female, white, stage:Stage IIIC, dead, 1279 days 822.9
TCGA-24-2288-01A 70 years, female, white, stage:Stage IIIC, dead, 25 days 815.8
TCGA-10-0928-01A 71 years, female, white, stage:Stage IIIC, dead, 563 days 782.8
TCGA-25-2393-01A 81 years, female, white, stage:Stage IIIC, dead, 1157 days 778.2
TCGA-25-2042-01A 60 years, female, american indian or alaska native, stage:Stage IIIC, dead, 396 days 757.7
TCGA-24-1474-01A 57 years, female, black or african american, stage:Stage IIIC, dead, 676 days 687.4
TCGA-24-1471-01A 60 years, female, white, stage:Stage IIIC, alive, 36 days 636.2
TCGA-20-1683-01A 65 years, female, white, stage:Stage IIIC, alive, 772 days 613.5
TCGA-30-1861-01A 74 years, female, white, stage:Stage IIIC, dead, 1058 days 597.1
TCGA-25-1632-01A 68 years, female, white, stage:Stage IV, dead, 1799 days 591.5
TCGA-04-1530-01A 68 years, female, white, stage:Stage IIIC, dead, 3622 days 584.2
TCGA-09-0369-01A 56 years, female, white, stage:Stage IIIC, dead, 1082 days 540.1
TCGA-29-1774-01A 82 years, female, white, stage:Stage IIIC, alive, 527 days 534.7
TCGA-59-A5PD-01A 55 years, female, black or african american, stage:Stage IC, dead, 624 days 533.5
TCGA-09-1673-01A 50 years, female, white, stage:Stage IV, alive, 92 days 494.4
TCGA-25-1877-01A 81 years, female, white, stage:Stage IIIC, dead, 730 days 490.9
TCGA-24-1550-01A 49 years, female, white, stage:Stage IIIC, dead, 1249 days 476.4
TCGA-24-1425-01A 45 years, female, white, stage:Stage IIIC, alive, 181 days 454.8
TCGA-25-1633-01A 64 years, female, white, stage:Stage IIIC, dead, 1891 days 439.9
TCGA-24-2020-01A 67 years, female, white, stage:Stage IIIC, dead, 4624 days 430.9
TCGA-30-1891-01A 61 years, female, white, stage:Stage IIIC, dead, 914 days 362.8
TCGA-29-1781-01A 69 years, female, white, stage:Stage IIIC, alive, 255 days 325.4
TCGA-24-1419-01A 62 years, female, white, stage:Stage IIIC, alive, 239 days 239.4
TCGA-04-1338-01A 78 years, female, white, stage:Stage IIIC, alive, 1418 days 235.8
TCGA-57-1582-01A 50 years, female, white, stage:Stage IIIC, dead, 731 days 195.8
TCGA-24-2035-01A 65 years, female, white, stage:Stage IIIC, dead, 857 days 126.4
TCGA-61-1721-01A 38 years, female, white, stage:Stage IV, alive, 338 days 71.9
TCGA-09-0364-01A 80 years, female, white, stage:Stage IIC, dead, 887 days 55.2
TCGA-61-2102-01A 74 years, female, white, stage:Stage IIIC, dead, 197 days 46.6
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OVARY SEROUS CYSTADENOCARCINOMA (VALIDATION) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

WFDC2 is not prognostic in Ovary Serous Cystadenocarcinoma (validation)


Stage:
Survival analysis
Current cut offi

Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

:
Best expression cut offi

Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

: 1836.13
Median expressioni

Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

: N/A
Median follow up timei

Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

: N/A
P scorei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

N/A
5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
TCGA RNA samplesi

RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average pTPM 2487.2
Number of samples 81
Samples
Sample Description pTPM
DO46404 55 years, female, NA, stage:III, dead, 690 days 12634.2
DO46463 49 years, female, NA, stage:III, dead, 2451 days 9228.2
DO46356 68 years, female, NA, stage:III, dead, 911 days 8551.8
DO46390 65 years, female, NA, stage:III, dead, 374 days 7224.1
DO46576 75 years, female, NA, stage:III, alive, 133 days 6918.9
DO46591 58 years, female, NA, stage:III, dead, 195 days 6005.4
DO46329 52 years, female, NA, stage:III, dead, 1699 days 5375.2
DO46468 67 years, female, NA, stage:III, alive, 2776 days 4682.5
DO46338 59 years, female, NA, stage:III, dead, 596 days 4672.5
DO46330 60 years, female, NA, stage:III, dead, 684 days 4138.8
DO46362 61 years, female, NA, stage:III, dead, 1639 days 4073.2
DO46586 55 years, female, NA, stage:III, dead, 1019 days 3754.5
DO46344 46 years, female, NA, stage:III, dead, 642 days 3706.1
DO46331 72 years, female, NA, stage:III, dead, 612 days 3678.5
DO46376 58 years, female, NA, stage:III, dead, 1430 days 3624.1
DO46382 62 years, female, NA, stage:IV, dead, 311 days 3600.7
DO46438 55 years, female, NA, stage:IV, alive, 2227 days 3393.6
DO46408 56 years, female, NA, stage:III, dead, 489 days 3344.9
DO46333 58 years, female, NA, stage:III, dead, 359 days 3275.1
DO46348 58 years, female, NA, stage:IV, dead, 287 days 3244.5
DO46358 60 years, female, NA, stage:III, dead, 423 days 3180.8
DO46538 57 years, female, NA, stage:III, dead, 1527 days 3168.5
DO46350 66 years, female, NA, stage:III, dead, 886 days 2915.6
DO46364 45 years, female, NA, stage:III, dead, 806 days 2888.2
DO46533 46 years, female, NA, stage:III, alive, 3667 days 2868.8
DO46611 52 years, female, NA, stage:III, dead, 734 days 2838.2
DO46493 62 years, female, NA, stage:IV, alive, 839 days 2759.6
DO46328 52 years, female, NA, stage:III, dead, 972 days 2573.5
DO46566 78 years, female, NA, stage:III, dead, 673 days 2560.8
DO46400 70 years, female, NA, stage:III, dead, 719 days 2373.7
DO46374 69 years, female, NA, stage:III, dead, 1409 days 2277.8
DO46597 60 years, female, NA, stage:III, dead, 393 days 2233.1
DO46428 59 years, female, NA, stage:IV, alive, 2644 days 2212.6
DO46394 61 years, female, NA, stage:IV, dead, 1039 days 2172.4
DO46560 45 years, female, NA, stage:IV, dead, 286 days 2157.3
DO46581 66 years, female, NA, stage:III, dead, 408 days 2103.4
DO46346 54 years, female, NA, stage:III, dead, 1187 days 2048.7
DO46370 54 years, female, NA, stage:III, dead, 1727 days 1987.8
DO46448 45 years, female, NA, stage:III, dead, 654 days 1956.4
DO46606 73 years, female, NA, stage:III, alive, 804 days 1870.7
DO46568 66 years, female, NA, stage:III, dead, 320 days 1862.2
DO46402 77 years, female, NA, stage:III, dead, 511 days 1838.8
DO46561 52 years, female, NA, stage:III, dead, 195 days 1836.1
DO46342 67 years, female, NA, stage:III, dead, 1398 days 1834.9
DO46436 58 years, female, NA, stage:III, alive, 3193 days 1831.4
DO46432 56 years, female, NA, stage:III, alive, 2218 days 1826.9
DO46546 73 years, female, NA, stage:III, dead, 1889 days 1758.9
DO46354 73 years, female, NA, stage:III, dead, 843 days 1752.4
DO46340 62 years, female, NA, stage:III, dead, 616 days 1733.6
DO46360 58 years, female, NA, stage:IV, dead, 1759 days 1577.7
DO46368 57 years, female, NA, stage:III, dead, 2879 days 1570.3
DO46378 59 years, female, NA, stage:III, alive, 843 days 1551.5
DO46334 77 years, female, NA, stage:III, dead, 496 days 1447.6
DO46366 65 years, female, NA, stage:III, dead, 2054 days 1424.4
DO46352 60 years, female, NA, stage:III, dead, 677 days 1422.6
DO46325 54 years, female, NA, stage:III, dead, 477 days 1415.2
DO46523 52 years, female, NA, stage:IV, alive, 1873 days 1326.8
DO46551 58 years, female, NA, stage:III, dead, 1055 days 1258.1
DO46528 56 years, female, NA, stage:III, alive, 6139 days 1256.6
DO46396 64 years, female, NA, stage:III, dead, 583 days 1246.6
DO46458 67 years, female, NA, stage:IV, alive, 3787 days 1186.7
DO46513 54 years, female, NA, stage:IV, dead, 1883 days 1171.9
DO46326 51 years, female, NA, stage:III, dead, 701 days 1154.4
DO46508 50 years, female, NA, stage:III, dead, 2101 days 1112.0
DO46386 49 years, female, NA, stage:III, dead, 1162 days 1054.0
DO46443 59 years, female, NA, stage:III, dead, 2464 days 989.1
DO46412 64 years, female, NA, stage:III, dead, 597 days 958.3
DO46336 70 years, female, NA, stage:IV, dead, 664 days 875.9
DO46388 74 years, female, NA, stage:III, dead, 413 days 871.5
DO46380 51 years, female, NA, stage:III, dead, 1423 days 802.9
DO46332 56 years, female, NA, stage:III, dead, 689 days 792.4
DO46398 66 years, female, NA, stage:III, alive, 437 days 757.0
DO46571 61 years, female, NA, stage:III, dead, 243 days 673.3
DO46588 74 years, female, NA, stage:III, dead, 438 days 659.8
DO46372 39 years, female, NA, stage:III, dead, 1326 days 591.7
DO46327 54 years, female, NA, stage:III, dead, 184 days 437.5
DO46453 66 years, female, NA, stage:III, dead, 3294 days 341.4
DO46392 48 years, female, NA, stage:III, dead, 628 days 334.4
DO46602 74 years, female, NA, stage:III, dead, 205 days 266.5
DO46518 62 years, female, NA, stage:III, alive, 2960 days 245.9
DO46384 55 years, female, NA, stage:III, dead, 614 days 141.5
Show allShow less
OVARY SEROUS CYSTADENOCARCINOMA - Protein relative expression (CPTAC)
Number of samples 108
Samples
Sample ID Sample type nRPX
31c15e30-21d4-4843-bd4a-9cd0d8_D2 Normal 2.7
161317f3-1a39-438e-af45-cd2502_D2 Tumor 2.6
3e746bea-ed68-40e6-b348-6ddf08_D2 Normal 2.5
092af714-b97a-457c-b0e9-8c20e8_D2 Normal 2.3
627e6e36-3dca-4ee5-9755-6f3510_D2 Tumor 2.1
49bd51fe-48a1-4828-b66e-b30c38_D2 Tumor 2.0
3dcf8b3c-c0c5-4dfa-9543-5d30fb_D2 Tumor 2.0
347e379b-77c0-4dd3-aa25-18c9d1_D2 Tumor 1.9
7d953d1d-84b6-4ecd-b1d7-1ed865_D2 Tumor 1.7
a03d1103-b809-42c4-ad5c-5aff58_D2 Tumor 1.7
5ea22f5e-307b-491d-801f-8b7fa6_D2 Tumor 1.6
c17b0ff9-9057-4848-a0cc-abb25f_D2 Tumor 1.5
1de8d3d8-fc0e-4be0-8aa7-127c7b_D2 Tumor 1.5
9c8e78bf-b03e-4ba0-9909-5ff070_D2 Tumor 1.4
2563cb02-d58a-4286-8634-7502cd_D2 Tumor 1.4
d38f40fb-dd78-43b2-8b7b-4b6977_D2 Tumor 1.4
2433b136-fc7b-4cea-b958-bc6efb_D2 Tumor 1.4
27f3ca2d-a86f-479d-8e7e-5307c7_D2 Tumor 1.3
52c064a7-78d9-4a1a-85b4-27c6d1_D2 Tumor 1.3
4ccb249a-6722-491e-97e9-e3b4e7_D2 Tumor 1.2
2f901c90-617e-46da-9fac-d68369_D2 Tumor 1.2
ce1e5dfc-2ef1-4633-af93-5ea4d9_D2 Tumor 1.2
0cc794c3-5bf5-4621-b238-58a0f6_D2 Tumor 1.1
3a380577-c134-47ba-a1ce-988d7c_D2 Tumor 1.1
eb3f3494-7057-4afe-b212-e6e9a3_D2 Tumor 1.0
0c87932d-b6fd-4eb5-b86a-a34d07_D2 Tumor 1.0
340a3769-3031-41ae-bb08-a2f696_D2 Normal 0.9
76e77c6b-c80e-4391-bdbb-e1dcea_D2 Tumor 0.9
318d53c3-216b-4de1-a098-77d6dd_D2 Tumor 0.8
a583d3ff-8165-43e9-b764-23b7ef_D1_D2 Normal 0.8
a65d8e76-640f-4341-a561-afbb57_D2 Normal 0.8
91b287fd-eadb-442d-abcd-20b741_D2 Tumor 0.8
2ed8beb2-bc63-4bad-b5fe-1916a0_D2 Tumor 0.6
e7b656bf-3c34-4ba1-bdf3-c7eefe_D2 Tumor 0.6
af95e2c6-25c4-4ab8-bf06-3e15ff_D2 Tumor 0.5
fe83e13f-9754-403b-8f74-d6caf8_D2 Tumor 0.5
1b2ab076-c72f-4bbe-b9f9-657d24_D2 Tumor 0.4
79b60f32-6cca-4cb6-9a1e-22a3ac_D2 Tumor 0.4
61f76fe6-a1c6-41b8-bdc2-2f9209_D2 Normal 0.4
b9c1f22e-61f7-45ed-b3b4-5094c7_D2 Normal 0.3
1c9145ad-1981-4871-aa7e-8b11de_D2 Tumor 0.3
8d78194e-fbef-4819-a7b5-b73ae9_D2 Tumor 0.3
8234f8ea-bdbd-45b0-bd0b-16f1e7_D2 Tumor 0.3
15524912-685a-47ce-a824-567848_D2 Tumor 0.3
41d0619e-b299-42e2-ac32-29e784_D2 Tumor 0.2
2115808b-6a0d-49bc-a8d7-b83bde_D2 Tumor 0.2
1abbcb28-f221-4cd4-8c01-37b9bb_D1_D2 Normal 0.2
1772e913-f62e-446a-8cf3-720348_D2 Tumor 0.2
eb0a53df-7620-4024-8d2d-051142_D2 Tumor 0.2
a3a26070-fb84-406a-8280-d555e6_D2 Normal 0.2
efc971f8-54c5-4531-a792-705ecf_D2 Tumor 0.1
42d860a3-8a0c-4c44-a09a-9ad8cf_D2 Tumor 0.1
285fed94-1495-448e-879b-b55de9_D2 Tumor 0.1
08296da7-70ea-44df-8646-09f2cc_D2 Tumor 0.0
1db5574d-aca7-403c-8100-6e705f_D2 Normal 0.0
9b90eb78-2f50-4aeb-b010-d642f9_D2 Tumor 0.0
7069e990-4a4e-4984-a66d-4d835a_D2 Tumor -0.1
256ac9f5-1e19-44b4-92fb-fef3fc_D2 Tumor -0.2
05387aad-2a1f-42c2-8d6f-950598_D3 Tumor -0.2
8ed739dd-ae0f-4881-971a-db3cf4_D1_D2 Normal -0.3
8e17b45e-6a06-4e4e-913d-7b1edb_D2 Tumor -0.3
cfd76f9a-ce60-4ec7-8e6b-a8fc31_D3 Tumor -0.3
10c2d629-0287-4511-ac25-f29031_D2 Tumor -0.3
51a4ce2f-4166-4c6b-a7e0-942d0a_D2 Tumor -0.3
e9d416e7-f661-400a-896e-388545_D2 Tumor -0.3
5c3971ee-87c7-4dff-b66e-f18892_D2 Tumor -0.3
7edfd606-4bee-4529-9fec-1ca7f0_D2 Normal -0.3
d4791079-c826-4fc7-9d9b-ee20ba_D2 Tumor -0.3
35a345a4-e954-4c81-ae3f-7797cd_D2 Tumor -0.4
50997c44-1c8b-4d34-b535-4a6cc2_D2 Tumor -0.4
7c7ce2d7-6c8a-424e-8e6c-d14ad1_D2 Tumor -0.5
b22659b9-e12c-4725-a7db-a833de_D1_D2 Normal -0.6
9a7a86d3-bbf2-4d36-941d-c75c03_D1_D2 Tumor -0.6
2dc28da8-7ff1-4b9b-b5bd-17cc25_D2 Tumor -0.6
69d552be-7cb2-4bb4-b602-a27b3e_D2 Tumor -0.6
9e0d47e0-f633-468b-b82b-4d752d_D2 Tumor -0.6
51c1c79e-5a8e-4b0a-bf92-1c0cab_D2 Tumor -0.6
927f0958-db5a-4bc5-92b7-2a3695_D2 Tumor -0.7
3946a96c-e0ae-442f-83b4-a9350e_D2 Tumor -0.7
28d0abdb-f682-4bd3-9425-a9c508_D2 Tumor -0.7
558333b0-ea23-4303-9e3c-4932b1_D2 Tumor -0.7
e3ebe010-cd31-4b5d-8fcb-b7103b_D2 Tumor -0.7
2b4ce90c-8036-4207-ac3e-54a76f_D2 Tumor -0.8
d109a3c0-350e-47f5-bda0-61899c_D2 Tumor -0.8
46c73531-f531-4ec3-97fe-b39d9d_D2 Tumor -0.9
6319b36b-533c-4e86-8e12-80552e_D3 Tumor -1.1
80873a0c-1f40-4d51-bab1-3f2071_D2 Tumor -1.1
2224c03f-b7b1-4368-887e-2b4cdf_D2 Tumor -1.3
74a45e5a-a35a-4c60-a4b4-f3f5ea_D2 Tumor -1.3
994f9b8e-46cb-413f-8ec8-2c2fed_D2 Normal -1.3
f6c215ea-5381-4521-bb61-be8e97_D2 Tumor -1.4
62f5840e-6cd7-4200-b651-645e53_D2 Tumor -1.4
0745488e-0bfb-4d1f-8228-dedf76_D1_D2 Normal -1.5
3490835c-c004-45ed-91f3-7c206f_D2 Tumor -1.6
21efd60f-6a31-4b98-9477-16a905_D2 Normal -1.7
2b73e01c-347a-4dae-a71d-752aeb_D2 Normal -1.8
e6850782-fd2a-4c53-b682-1852fe_D2 Tumor -2.0
685ec3c2-e67a-40d3-9eb3-aa01c9_D1_D2 Normal -2.0
e23eb014-69c1-460a-b9d4-9786c8_D2 Normal -2.2
6e209757-a7f4-45af-b5f3-2ebc02_D2 Normal -4.4
1556af7e-c2ae-4fce-9aae-87c459_D1_D2 Normal N/A
a8853382-b726-4ce8-98d5-ca89df_D2 Tumor N/A
6530147a-efe9-4df6-ac2f-03ece3_D2 Tumor N/A
3fbf076a-824b-4eac-b6dc-bf5e59_D2 Normal N/A
bd266bdd-12e4-42cb-9c49-911bfc_D2 Tumor N/A
3d3e1888-d67e-4c69-ba83-112d0f_D2 Tumor N/A
fbb41c94-aabd-49cc-90b2-882c3e_D2 Tumor N/A
1a10c200-3895-4648-b951-94f99f_D2 Tumor N/A
Show allShow less
OVARIAN CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


Antibody HPA042302
 Staining
  High
  Medium
  Low
  Not detected
 Intensity
  Strong
  Moderate
  Weak
  Negative
 Quantity
  >75%
  75%-25%
  <25%
  None
 Location
  Nuclear
  Cytoplasmic/membranous
  Cytoplasmic/membranous,nuclear
  None
Cystadenocarcinoma, serous, NOS
Carcinoma, endometroid
Cystadenocarcinoma, mucinous, NOS
Carcinoma, NOS
Cystadenocarcinoma, serous, NOS

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