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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
51.9
nTPM
HPA:
38.4
nTPM
GTEx:
51.9
nTPM
FANTOM5:
55.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA007649
Antibody HPA052474
Antibody HPA052484
Antibody CAB037174
Cholangiocytes
Not detected
Not detected
Not detected
Not detected
Hepatocytes
Medium
Not detected
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
38.4
Female, age 60
Liver sample 21 nTPM: 55.2
Male, age 54
Liver sample 23 nTPM: 37.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 48.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 14.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 27.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 32
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 79.5
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 42.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 40.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
51.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 51.9
Samples: 226
Max nTPM: 179.5
Min nTPM: 6.8
Std nTPM: 32.4
Median nTPM: 45.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
179.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
174.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
165.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
135.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
129.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
128.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
126.0
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
125.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
121.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
118.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
114.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
112.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
108.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
105.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
103.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
102.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
102.1
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
99.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
98.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
95.6
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
94.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
93.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
93.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
92.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
91.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
90.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
90.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
89.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
88.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
87.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
87.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
86.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
86.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
85.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
85.2
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
85.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
85.0
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
84.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
83.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
83.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
81.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
80.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
80.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
80.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
80.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
80.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
80.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
79.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
79.4
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
79.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
77.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
77.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
77.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
76.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
76.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
75.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
73.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
73.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
69.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
68.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
68.8
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
68.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
68.8
GTEX-18465-1626-SM-7LG6N
50-59 years, male
68.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
65.4
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
65.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
64.6
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
64.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
64.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
64.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
63.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
62.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
62.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
62.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
62.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
61.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
61.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
60.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
60.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
60.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
59.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
59.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
59.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
59.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
58.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
57.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
57.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
56.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
54.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
53.9
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
53.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
52.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
52.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
52.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
52.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
51.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
51.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
50.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
50.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
49.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
49.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
49.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
49.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
48.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
47.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
47.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
47.5
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
47.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
45.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
45.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
45.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
45.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
45.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
45.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
44.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
44.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
43.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
42.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
42.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
41.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
41.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
41.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
39.3
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
39.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
38.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
38.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
38.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
38.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
37.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
37.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
37.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
37.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
36.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
36.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
36.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
35.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
35.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
35.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
35.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
34.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
34.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
34.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
34.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
33.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
32.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
32.4
GTEX-S33H-1626-SM-4AD68
30-39 years, male
32.1
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
32.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
31.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
31.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
31.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
31.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
31.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
31.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
30.9
GTEX-14PJO-1726-SM-68719
60-69 years, male
30.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
30.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
29.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
29.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
28.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
28.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
28.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
27.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
27.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
27.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
27.0
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
26.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
26.5
GTEX-17F96-1226-SM-79OK2
70-79 years, male
26.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
26.0
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
26.0
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
25.6
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
25.3
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
25.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
24.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
24.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
23.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
23.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
23.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
23.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
23.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
22.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
22.4
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
21.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
21.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
21.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
21.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
21.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
20.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
20.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
20.6
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
19.6
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
19.2
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
19.2
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
19.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
19.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
19.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
18.7
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
18.5
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
18.4
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
17.8
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
17.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
17.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
17.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
17.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
17.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
17.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
16.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
16.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
15.4
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
15.0
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
14.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
14.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
14.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
14.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
14.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
13.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
13.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
12.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
12.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
12.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
11.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
11.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
11.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
9.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
6.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
