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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:35.8 nTPM
HPA Brain:139.1 nTPM
GTEx:35.8 nTPM
FANTOM5:3.2 Scaled Tags Per Million
Pig:53.6 nTPM
Mouse:107.0 nTPM
Allen mouse:9.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

139.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 70.3
2219 Male, age 76, both hemispheres 112.3
1827 Male, age 72, unknown 101.5
2666 Male, age 74, left hemisphere 91.2
2828 Female, age 72, unknown 80.2
2411 Female, age 72, unknown 69.8
1870 Female, age 42, unknown 67.1
1833 Male, age 53, unknown 56.5
2586 Male, age 75, left hemisphere 50.2
1830 Male, age 51, unknown 48.3
2019 Male, age 18, unknown 25.7
Dorsal raphe nucleus
nTPM: 79.5
2298 Female, age 72, unknown 111.1
2750 Male, age 76, both hemispheres 88.1
2047 Male, age 72, unknown 86.3
1828 Male, age 53, unknown 59.1
2016 Female, age 72, unknown 53.2
Inferior colliculus
nTPM: 64.9
2097 Female, age 72, unknown 79.5
2849 Male, age 72, unknown 64.9
1848 Female, age 42, unknown 64.2
1890 Male, age 53, unknown 51.0
Median raphe nucleus
nTPM: 139.1
2220 Male, age 76, midline 139.1
Periaquaductal grey, anterior
nTPM: 116.7
2502 Female, age 75, unknown 124.5
1795 Male, age 51, unknown 116.5
1947 Male, age 18, unknown 109.1
Periaquaductal grey, dorsal
nTPM: 80.7
1840 Male, age 53, unknown 99.2
1831 Male, age 72, unknown 79.3
2850 Male, age 76, both hemispheres 78.9
2464 Female, age 72, unknown 65.1
Periaquaductal grey, lateral
nTPM: 70.1
2053 Male, age 18, unknown 87.2
2140 Male, age 76, both hemispheres 72.0
2272 Male, age 74, both hemispheres 51.3
Pretectal area
nTPM: 75.1
2224 Female, age 72, unknown 111.3
1816 Male, age 51, unknown 108.1
2825 Male, age 18, unknown 94.5
1944 Female, age 72, unknown 85.9
2316 Male, age 76, right hemisphere 77.3
2667 Female, age 75, unknown 77.2
1815 Male, age 53, unknown 69.2
2007 Male, age 72, unknown 63.6
1817 Female, age 42, unknown 58.6
2407 Male, age 75, both hemispheres 48.5
2273 Male, age 74, both hemispheres 31.7
Red nucleus
nTPM: 31.1
2584 Male, age 75, left hemisphere 51.3
2503 Female, age 72, unknown 35.7
1821 Female, age 72, unknown 32.7
2227 Male, age 72, unknown 31.5
1954 Female, age 42, unknown 31.2
2785 Male, age 18, unknown 30.7
2769 Male, age 72, unknown 30.6
1904 Male, age 53, unknown 27.7
2725 Female, age 75, unknown 27.2
2588 Male, age 74, left hemisphere 25.8
2823 Male, age 76, right hemisphere 24.9
1865 Male, age 51, unknown 24.0
Substantia nigra
nTPM: 88.8
1916 Female, age 42, unknown 138.8
2665 Male, age 74, both hemispheres 120.9
1941 Male, age 53, unknown 107.4
1851 Male, age 51, unknown 103.8
2241 Male, age 72, unknown 92.8
2699 Male, age 18, unknown 91.5
1889 Female, age 72, unknown 71.2
2409 Female, age 72, unknown 69.1
2590 Female, age 75, unknown 49.4
2583 Male, age 75, right hemisphere 43.0
Superior colliculus
nTPM: 75.4
2668 Female, age 75, unknown 115.4
1796 Male, age 53, unknown 112.7
2261 Male, age 18, unknown 101.9
2087 Female, age 72, unknown 83.4
2664 Male, age 75, both hemispheres 73.0
1895 Male, age 76, right hemisphere 66.9
1839 Male, age 51, unknown 65.0
2587 Male, age 74, left hemisphere 48.6
1913 Female, age 42, unknown 47.8
1995 Male, age 72, unknown 39.0
Ventral tegmental area
nTPM: 94.7
2218 Male, age 76, both hemispheres 138.6
1915 Female, age 42, unknown 101.4
2410 Female, age 72, unknown 96.3
1942 Male, age 51, unknown 90.5
2021 Male, age 53, unknown 77.0
2223 Female, age 72, unknown 64.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

35.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 35.8
Samples: 139

Max nTPM: 117.6
Min nTPM: 1.2
Std nTPM: 26.8
Median nTPM: 30.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 117.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 115.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 107.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 101.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 88.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 87.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 86.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 83.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 83.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 77.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 74.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 73.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 73.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 73.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 70.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 69.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 65.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 64.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 63.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 63.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 62.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 61.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 59.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 58.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 57.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 57.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 56.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 53.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 53.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 53.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 52.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 51.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 51.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 51.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 51.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 50.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 49.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 49.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 48.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 46.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 45.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 45.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 45.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 45.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 44.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 44.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 44.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 43.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 42.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 41.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 41.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 39.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 39.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 39.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 37.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 36.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 35.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 35.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 33.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 33.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 31.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 31.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 30.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 30.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 29.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 29.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 27.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 26.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 26.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 26.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 25.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 25.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 25.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 25.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 24.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 23.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 23.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 23.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 21.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 21.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 21.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 19.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 18.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 18.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 17.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 17.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 17.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 17.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 17.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 16.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 16.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 16.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 15.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 15.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 15.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 15.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 14.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 12.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 12.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 12.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 11.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 11.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 10.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 10.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 9.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 9.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 9.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 8.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 8.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 8.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 8.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 7.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 7.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 7.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 7.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 6.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 6.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 5.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 5.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 3.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 3.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 3.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

3.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 3.2
FF:10158-103A5 76 years, female 3.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

53.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 53.0
Samples: 4

Max nTPM: 91.3
Min nTPM: 14.1
Sample A Female 70.3
Sample B Female 36.1
Sample C Male 91.3
Sample D Male 14.1
Midbrain
nTPM: 53.6
Samples: 4

Max nTPM: 86.8
Min nTPM: 10.9
Sample A Female 10.9
Sample B Female 45.0
Sample C Male 86.8
Sample D Male 71.7
Periaqueductal gray
nTPM: 46.6
Samples: 3

Max nTPM: 63.1
Min nTPM: 37.3
Sample B Female 39.4
Sample C Male 63.1
Sample D Male 37.3
Superior colliculi
nTPM: 40.4
Samples: 4

Max nTPM: 47.0
Min nTPM: 24.5
Sample A Female 44.3
Sample B Female 24.5
Sample C Male 45.8
Sample D Male 47.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 107.0
Samples: 4

Max nTPM: 117.1
Min nTPM: 99.7
Sample A Male 117.1
Sample B Male 105.0
Sample C Female 99.7
Sample D Female 106.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.3
69013010 Antisense, RP_050309_01_H01, Mouse strain C57BL/6J (56 days, male) 14.8
73592527 Antisense, RP_051017_01_E03, Mouse strain C57BL/6J (56 days, male) 13.0
71161411 Antisense, RP_050810_01_C05, Mouse strain C57BL/6J (56 days, male) 0.0

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