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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
195.9
nTPM
HPA:
195.9
nTPM
GTEx:
80.4
nTPM
FANTOM5:
521.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA020433
Cholangiocytes
Medium
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
195.9
Female, age 60
Liver sample 21 nTPM: 168.5
Male, age 54
Liver sample 23 nTPM: 150.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 206.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 227.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 210.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 202.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 199.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 160.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 221.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 212.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
80.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 80.4
Samples: 226
Max nTPM: 305.5
Min nTPM: 7.3
Std nTPM: 49.1
Median nTPM: 75.5
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
305.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
279.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
266.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
260.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
222.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
220.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
216.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
188.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
181.1
GTEX-14XAO-0226-SM-68728
60-69 years, female
179.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
176.4
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
168.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
167.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
161.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
148.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
144.6
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
143.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
141.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
141.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
139.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
137.3
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
135.8
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
135.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
135.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
134.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
133.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
133.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
128.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
126.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
125.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
125.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
123.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
123.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
123.3
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
123.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
120.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
119.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
118.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
117.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
116.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
115.0
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
114.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
114.4
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
114.0
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
114.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
111.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
111.4
GTEX-18A66-2026-SM-7189C
60-69 years, male
108.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
107.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
106.9
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
106.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
106.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
106.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
106.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
104.9
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
104.3
GTEX-14JG1-1626-SM-664NH
40-49 years, male
104.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
103.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
103.7
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
102.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
102.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
101.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
99.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
98.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
98.4
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
98.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
98.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
97.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
96.7
GTEX-R53T-0326-SM-48FEC
50-59 years, female
94.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
94.0
GTEX-QESD-2026-SM-447BI
20-29 years, male
93.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
93.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
91.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
91.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
90.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
90.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
90.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
89.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
88.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
88.3
GTEX-14E7W-1526-SM-6871X
70-79 years, male
88.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
88.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
87.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
86.4
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
86.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
85.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
84.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
83.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
83.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
83.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
83.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
82.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
81.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
80.9
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
80.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
80.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
80.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
80.3
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
79.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
79.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
78.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
78.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
77.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
77.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
77.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
77.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
77.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
77.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
76.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
76.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
76.2
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
75.6
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
75.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
75.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
73.8
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
71.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
71.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
70.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
68.7
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
68.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
68.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
67.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
66.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
66.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
66.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
64.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
64.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
64.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
64.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
63.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
63.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
62.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
62.9
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
62.4
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
62.2
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
61.9
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
61.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
61.5
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
60.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
59.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
58.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
58.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
58.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
56.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
56.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
55.7
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
55.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
55.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
55.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
55.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
54.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
53.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
53.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
52.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
52.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
52.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
52.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
51.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
51.3
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
51.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
49.0
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
48.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
48.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
48.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
48.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
47.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
47.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
47.8
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
47.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
47.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
47.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
47.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
46.0
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
45.2
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
44.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
44.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
42.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
41.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
40.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
39.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
39.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
39.3
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
39.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
38.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
37.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
36.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
35.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
35.0
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
34.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
33.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
33.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
33.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
31.7
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
30.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
30.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
30.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
29.8
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
29.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
28.9
GTEX-RN64-1826-SM-48FDV
50-59 years, male
28.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
26.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
26.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
26.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
25.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
24.8
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
24.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
24.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
24.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
24.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
23.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
23.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
23.1
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
21.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
20.8
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
20.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
18.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
18.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
17.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
17.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
17.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
16.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
13.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
10.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
9.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
7.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
