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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:66.2 nTPM
HPA Brain:206.9 nTPM
GTEx:66.2 nTPM
FANTOM5:76.2 Scaled Tags Per Million
Pig:85.4 nTPM
Mouse:99.9 nTPM
Allen mouse:13.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

206.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 156.2
1827 Male, age 72, unknown 193.5
2666 Male, age 74, left hemisphere 179.2
2411 Female, age 72, unknown 178.6
1870 Female, age 42, unknown 170.8
1833 Male, age 53, unknown 160.6
2586 Male, age 75, left hemisphere 158.5
2219 Male, age 76, both hemispheres 146.7
2828 Female, age 72, unknown 145.3
1830 Male, age 51, unknown 134.5
2019 Male, age 18, unknown 94.3
Dorsal raphe nucleus
nTPM: 171.2
2298 Female, age 72, unknown 219.8
2047 Male, age 72, unknown 180.2
1828 Male, age 53, unknown 156.6
2750 Male, age 76, both hemispheres 155.9
2016 Female, age 72, unknown 143.5
Inferior colliculus
nTPM: 186.4
2849 Male, age 72, unknown 202.2
2097 Female, age 72, unknown 201.1
1848 Female, age 42, unknown 191.0
1890 Male, age 53, unknown 151.4
Median raphe nucleus
nTPM: 189.6
2220 Male, age 76, midline 189.6
Periaquaductal grey, anterior
nTPM: 206.9
1947 Male, age 18, unknown 233.1
1795 Male, age 51, unknown 196.7
2502 Female, age 75, unknown 191.0
Periaquaductal grey, dorsal
nTPM: 182.1
1840 Male, age 53, unknown 226.4
2850 Male, age 76, both hemispheres 173.8
1831 Male, age 72, unknown 164.8
2464 Female, age 72, unknown 163.3
Periaquaductal grey, lateral
nTPM: 178.2
2053 Male, age 18, unknown 193.3
2140 Male, age 76, both hemispheres 176.2
2272 Male, age 74, both hemispheres 165.0
Pretectal area
nTPM: 171.4
2224 Female, age 72, unknown 221.3
2825 Male, age 18, unknown 217.6
1816 Male, age 51, unknown 191.3
2667 Female, age 75, unknown 174.6
1944 Female, age 72, unknown 164.1
2273 Male, age 74, both hemispheres 164.0
2316 Male, age 76, right hemisphere 160.6
2007 Male, age 72, unknown 153.4
1815 Male, age 53, unknown 149.1
1817 Female, age 42, unknown 147.1
2407 Male, age 75, both hemispheres 142.5
Red nucleus
nTPM: 127.0
1821 Female, age 72, unknown 150.6
2584 Male, age 75, left hemisphere 142.1
2725 Female, age 75, unknown 137.6
2769 Male, age 72, unknown 131.3
1954 Female, age 42, unknown 129.9
2227 Male, age 72, unknown 129.5
2503 Female, age 72, unknown 127.5
2588 Male, age 74, left hemisphere 125.8
1904 Male, age 53, unknown 122.6
1865 Male, age 51, unknown 112.5
2823 Male, age 76, right hemisphere 112.1
2785 Male, age 18, unknown 102.1
Substantia nigra
nTPM: 153.7
1916 Female, age 42, unknown 191.1
2241 Male, age 72, unknown 176.2
1851 Male, age 51, unknown 164.0
1889 Female, age 72, unknown 153.6
2699 Male, age 18, unknown 151.7
2590 Female, age 75, unknown 146.8
2665 Male, age 74, both hemispheres 145.1
1941 Male, age 53, unknown 141.6
2583 Male, age 75, right hemisphere 135.1
2409 Female, age 72, unknown 131.5
Superior colliculus
nTPM: 158.2
2261 Male, age 18, unknown 198.8
1796 Male, age 53, unknown 198.2
1839 Male, age 51, unknown 177.9
1895 Male, age 76, right hemisphere 174.4
2087 Female, age 72, unknown 159.6
2664 Male, age 75, both hemispheres 157.4
2668 Female, age 75, unknown 155.3
2587 Male, age 74, left hemisphere 143.6
1913 Female, age 42, unknown 112.9
1995 Male, age 72, unknown 104.1
Ventral tegmental area
nTPM: 173.5
1915 Female, age 42, unknown 187.3
2218 Male, age 76, both hemispheres 181.5
2021 Male, age 53, unknown 172.5
2410 Female, age 72, unknown 170.7
1942 Male, age 51, unknown 167.5
2223 Female, age 72, unknown 161.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 66.2
Samples: 139

Max nTPM: 147.5
Min nTPM: 32.1
Std nTPM: 20.8
Median nTPM: 61.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 147.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 128.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 123.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 115.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 113.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 112.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 110.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 110.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 104.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 104.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 103.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 100.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 98.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 98.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 96.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 94.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 93.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 92.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 92.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 86.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 85.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 83.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 83.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 82.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 81.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 80.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 80.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 79.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 79.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 79.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 79.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 78.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 78.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 77.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 76.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 75.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 75.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 74.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 74.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 73.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 73.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 72.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 71.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 71.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 70.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 70.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 69.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 69.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 69.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 69.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 69.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 68.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 68.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 67.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 66.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 66.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 65.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 65.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 64.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 63.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 63.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 63.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 62.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 62.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 62.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 62.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 61.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 61.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 61.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 60.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 60.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 59.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 59.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 58.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 58.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 58.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 58.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 57.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 57.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 56.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 56.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 56.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 55.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 55.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 54.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 54.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 54.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 54.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 54.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 54.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 53.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 53.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 53.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 53.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 52.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 51.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 51.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 51.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 50.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 50.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 50.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 50.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 50.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 49.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 49.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 49.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 48.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 48.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 48.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 48.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 47.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 47.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 47.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 47.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 46.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 46.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 45.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 45.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 45.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 45.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 44.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 44.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 44.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 44.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 43.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 41.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 41.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 41.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 39.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 37.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 37.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 37.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 37.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 32.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

76.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 76.2
FF:10158-103A5 76 years, female 76.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

85.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 68.0
Samples: 4

Max nTPM: 90.5
Min nTPM: 42.2
Sample A Female 90.5
Sample B Female 52.9
Sample C Male 86.5
Sample D Male 42.2
Midbrain
nTPM: 77.9
Samples: 4

Max nTPM: 105.5
Min nTPM: 50.0
Sample A Female 50.0
Sample B Female 60.1
Sample C Male 105.5
Sample D Male 95.8
Periaqueductal gray
nTPM: 67.2
Samples: 3

Max nTPM: 80.6
Min nTPM: 57.1
Sample B Female 64.0
Sample C Male 80.6
Sample D Male 57.1
Superior colliculi
nTPM: 85.5
Samples: 4

Max nTPM: 95.4
Min nTPM: 66.4
Sample A Female 95.4
Sample B Female 66.4
Sample C Male 93.3
Sample D Male 86.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

99.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 99.9
Samples: 4

Max nTPM: 102.7
Min nTPM: 95.1
Sample A Male 95.1
Sample B Male 102.3
Sample C Female 102.7
Sample D Female 99.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

13.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.0
77620309 Antisense, RP_070205_01_A10, Mouse strain C57BL/6J (56 days, male) 14.3
355883 Antisense, RP_040617_01_F01, Mouse strain C57BL/6J (56 days, male) 11.6
293903 Antisense, RP_040617_01_F01, Mouse strain C57BL/6J (56 days, male) 10.6
77869130 Antisense, RP_070205_01_A10, Mouse strain C57BL/6J (56 days, male) 8.4

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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