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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
103.2
nTPM
HPA:
22.1
nTPM
GTEx:
103.2
nTPM
FANTOM5:
6.8
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA010123
Cholangiocytes
Medium
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
22.1
Female, age 60
Liver sample 21 nTPM: 24.8
Male, age 54
Liver sample 23 nTPM: 34.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 17.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 14.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 13.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 19.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 36.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 32.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 13.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 15.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
103.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 103.2
Samples: 226
Max nTPM: 642.1
Min nTPM: 17.6
Std nTPM: 77.2
Median nTPM: 86.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
642.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
471.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
372.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
331.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
324.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
308.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
280.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
258.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
255.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
250.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
248.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
246.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
241.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
232.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
225.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
222.9
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
211.1
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
203.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
202.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
195.8
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
189.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
186.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
183.8
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
183.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
174.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
174.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
173.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
173.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
172.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
171.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
171.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
168.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
165.3
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
164.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
161.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
161.6
GTEX-1B932-1426-SM-793AN
40-49 years, female
161.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
158.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
155.7
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
155.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
155.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
152.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
145.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
144.9
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
144.0
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
141.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
140.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
139.5
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
136.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
136.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
134.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
131.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
131.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
130.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
130.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
129.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
128.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
127.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
127.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
127.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
126.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
126.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
125.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
124.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
124.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
123.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
122.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
122.6
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
121.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
120.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
119.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
119.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
118.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
115.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
115.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
114.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
114.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
113.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
113.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
112.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
112.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
109.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
108.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
107.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
105.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
104.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
104.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
104.3
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
103.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
102.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
101.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
100.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
98.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
94.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
94.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
93.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
92.1
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
92.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
92.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
91.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
91.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
91.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
90.4
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
90.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
89.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
88.6
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
88.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
87.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
87.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
87.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
87.0
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
87.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
86.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
86.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
85.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
85.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
85.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
83.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
82.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
81.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
80.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
80.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
80.0
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
79.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
77.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
76.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
75.8
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
74.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
74.3
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
74.2
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
73.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
73.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
72.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
72.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
72.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
72.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
72.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
71.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
70.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
69.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
69.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
68.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
68.4
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
68.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
68.2
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
67.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
66.9
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
66.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
64.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
63.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
63.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
61.7
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
61.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
61.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
61.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
59.2
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
58.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
57.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
57.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
57.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
56.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
55.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
55.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
53.6
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
52.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
51.7
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
50.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
50.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
50.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
49.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
49.8
GTEX-1B933-1226-SM-731DW
50-59 years, female
49.7
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
48.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
48.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
47.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
47.5
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
47.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
46.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
46.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
46.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
45.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
45.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
44.9
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
44.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
43.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
43.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
42.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
41.8
GTEX-18465-1626-SM-7LG6N
50-59 years, male
41.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
41.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
41.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
40.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
40.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
40.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
39.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
37.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
37.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
37.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
37.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
37.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
37.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
36.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
36.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
35.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
32.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
32.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
32.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
31.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
31.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
30.9
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
29.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
29.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
28.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
27.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
26.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
25.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
23.4
GTEX-144GL-1426-SM-79OMA
50-59 years, male
22.9
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
22.7
GTEX-13112-1426-SM-5EGH8
50-59 years, male
22.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
22.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
21.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
20.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
19.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
19.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
17.6
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
