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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:142.4 nTPM
HPA Brain:94.0 nTPM
GTEx:142.4 nTPM
FANTOM5:95.6 Scaled Tags Per Million
Pig:108.2 nTPM
Mouse:123.5 nTPM
Allen mouse:4.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

94.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 89.7
2586 Male, age 75, left hemisphere 142.2
2666 Male, age 74, left hemisphere 101.9
2019 Male, age 18, unknown 94.9
1827 Male, age 72, unknown 92.1
2411 Female, age 72, unknown 89.3
2828 Female, age 72, unknown 82.7
2219 Male, age 76, both hemispheres 80.0
1870 Female, age 42, unknown 76.8
1830 Male, age 51, unknown 69.0
1833 Male, age 53, unknown 67.9
Dorsal raphe nucleus
nTPM: 84.5
2047 Male, age 72, unknown 92.8
2298 Female, age 72, unknown 91.4
1828 Male, age 53, unknown 91.2
2750 Male, age 76, both hemispheres 76.5
2016 Female, age 72, unknown 70.5
Inferior colliculus
nTPM: 78.5
2097 Female, age 72, unknown 84.9
1890 Male, age 53, unknown 78.8
2849 Male, age 72, unknown 76.4
1848 Female, age 42, unknown 74.0
Median raphe nucleus
nTPM: 83.3
2220 Male, age 76, midline 83.3
Periaquaductal grey, anterior
nTPM: 94.0
1795 Male, age 51, unknown 100.7
2502 Female, age 75, unknown 94.4
1947 Male, age 18, unknown 87.0
Periaquaductal grey, dorsal
nTPM: 70.3
1840 Male, age 53, unknown 82.6
1831 Male, age 72, unknown 67.8
2464 Female, age 72, unknown 67.8
2850 Male, age 76, both hemispheres 62.9
Periaquaductal grey, lateral
nTPM: 62.9
2053 Male, age 18, unknown 65.6
2140 Male, age 76, both hemispheres 61.8
2272 Male, age 74, both hemispheres 61.3
Pretectal area
nTPM: 88.0
1817 Female, age 42, unknown 118.2
2007 Male, age 72, unknown 116.7
1816 Male, age 51, unknown 111.9
1944 Female, age 72, unknown 103.2
1815 Male, age 53, unknown 96.7
2667 Female, age 75, unknown 82.8
2224 Female, age 72, unknown 72.7
2825 Male, age 18, unknown 72.5
2407 Male, age 75, both hemispheres 69.9
2273 Male, age 74, both hemispheres 64.8
2316 Male, age 76, right hemisphere 58.3
Red nucleus
nTPM: 80.5
2785 Male, age 18, unknown 96.5
2588 Male, age 74, left hemisphere 96.4
2503 Female, age 72, unknown 90.8
2584 Male, age 75, left hemisphere 89.1
1821 Female, age 72, unknown 85.2
2769 Male, age 72, unknown 82.2
2725 Female, age 75, unknown 77.0
2227 Male, age 72, unknown 76.1
1954 Female, age 42, unknown 75.1
1865 Male, age 51, unknown 70.2
1904 Male, age 53, unknown 67.4
2823 Male, age 76, right hemisphere 60.1
Substantia nigra
nTPM: 92.5
1916 Female, age 42, unknown 122.8
1851 Male, age 51, unknown 110.0
2665 Male, age 74, both hemispheres 107.4
1889 Female, age 72, unknown 98.5
1941 Male, age 53, unknown 94.4
2583 Male, age 75, right hemisphere 90.7
2699 Male, age 18, unknown 82.4
2241 Male, age 72, unknown 76.8
2409 Female, age 72, unknown 71.4
2590 Female, age 75, unknown 70.9
Superior colliculus
nTPM: 84.9
2668 Female, age 75, unknown 114.5
2664 Male, age 75, both hemispheres 98.6
1796 Male, age 53, unknown 94.1
2087 Female, age 72, unknown 91.0
2261 Male, age 18, unknown 86.3
2587 Male, age 74, left hemisphere 76.1
1839 Male, age 51, unknown 74.8
1895 Male, age 76, right hemisphere 73.4
1913 Female, age 42, unknown 73.1
1995 Male, age 72, unknown 67.5
Ventral tegmental area
nTPM: 86.5
1915 Female, age 42, unknown 98.0
2410 Female, age 72, unknown 94.7
2218 Male, age 76, both hemispheres 87.0
1942 Male, age 51, unknown 82.2
2223 Female, age 72, unknown 79.6
2021 Male, age 53, unknown 77.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

142.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 142.4
Samples: 139

Max nTPM: 281.8
Min nTPM: 72.2
Std nTPM: 35.2
Median nTPM: 138.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 281.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 237.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 235.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 233.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 211.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 209.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 207.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 204.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 199.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 194.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 193.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 193.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 193.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 190.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 188.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 184.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 183.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 180.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 177.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 176.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 175.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 174.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 171.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 170.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 169.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 169.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 168.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 167.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 167.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 165.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 165.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 164.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 164.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 164.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 161.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 161.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 159.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 158.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 157.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 157.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 156.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 154.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 154.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 154.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 153.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 153.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 153.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 153.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 153.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 152.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 152.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 152.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 151.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 150.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 150.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 149.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 148.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 148.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 146.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 145.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 145.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 144.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 143.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 143.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 143.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 143.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 142.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 139.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 139.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 138.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 137.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 137.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 137.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 136.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 136.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 136.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 135.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 135.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 134.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 134.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 134.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 133.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 133.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 132.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 132.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 132.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 130.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 129.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 129.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 128.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 128.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 128.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 127.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 126.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 126.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 125.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 125.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 125.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 125.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 124.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 123.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 122.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 121.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 121.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 120.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 118.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 117.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 113.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 111.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 111.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 109.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 108.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 108.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 107.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 107.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 106.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 106.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 105.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 105.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 104.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 104.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 103.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 100.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 99.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 99.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 99.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 97.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 96.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 96.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 95.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 95.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 95.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 94.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 91.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 84.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 81.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 78.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 77.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 72.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

95.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 95.6
FF:10158-103A5 76 years, female 95.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

108.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 103.4
Samples: 4

Max nTPM: 140.6
Min nTPM: 70.9
Sample A Female 140.6
Sample B Female 80.6
Sample C Male 121.4
Sample D Male 70.9
Midbrain
nTPM: 103.6
Samples: 4

Max nTPM: 119.3
Min nTPM: 90.7
Sample A Female 109.5
Sample B Female 90.7
Sample C Male 119.3
Sample D Male 95.0
Periaqueductal gray
nTPM: 85.6
Samples: 3

Max nTPM: 99.2
Min nTPM: 75.8
Sample B Female 81.9
Sample C Male 99.2
Sample D Male 75.8
Superior colliculi
nTPM: 108.2
Samples: 4

Max nTPM: 126.2
Min nTPM: 90.3
Sample A Female 126.2
Sample B Female 90.3
Sample C Male 112.7
Sample D Male 103.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

123.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 123.5
Samples: 4

Max nTPM: 129.6
Min nTPM: 115.9
Sample A Male 129.6
Sample B Male 115.9
Sample C Female 122.0
Sample D Female 126.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.7
71608348 Antisense, RP_050927_01_E04, Mouse strain C57BL/6J (56 days, male) 7.0
77620401 Antisense, RP_070205_01_F10, Mouse strain C57BL/6J (56 days, male) 3.7
79912552 Antisense, RP_080109_01_B07, Mouse strain C57BL/6J (56 days, male) 3.4

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