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UBE2I
HPA
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  • SUMMARY

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  • UBE2I
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

UBE2I
Synonyms UBC9
Gene descriptioni

Full gene name according to HGNC.

Ubiquitin conjugating enzyme E2 I
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Cancer-related genes
Metabolic proteins
Plasma proteins
Transporters
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 16
Cytoband p13.3
Chromosome location (bp) 1308880 - 1327018
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

11
Ensembl ENSG00000103275 (version 109)
Entrez gene 7329
HGNC HGNC:12485
UniProt P63279 (UniProt - Evidence at protein level)
neXtProt NX_P63279
GeneCards UBE2I
Antibodypedia UBE2I antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity 1.... show less
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

Transferase
Biological process (UniProt)i

Keywords assigned by UniProt to proteins because they are involved in a particular biological process.

Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Ubl conjugation pathway
Ligand (UniProt)i

Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.

ATP-binding, Nucleotide-binding
Gene summary (Entrez)i

Useful information about the gene from Entrez

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
UBE2I-201
ENSP00000324897
ENST00000325437
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-202
ENSP00000348056
ENST00000355803
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-203
ENSP00000380649
ENST00000397514
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016604 [nuclear body]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043398 [HLH domain binding]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-204
ENSP00000380650
ENST00000397515
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-205
ENSP00000384361
ENST00000402301
B0QYN7
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0005524 [ATP binding]
GO:0016740 [transferase activity]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0032446 [protein modification by small protein conjugation]
Show all
184 aa
20.5 kDa
No 0
UBE2I-206
ENSP00000385009
ENST00000403747
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-207
ENSP00000384568
ENST00000406620
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-209
ENSP00000490882
ENST00000562470
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-213
ENSP00000457064
ENST00000566587
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-215
ENSP00000455893
ENST00000567074
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
H3BQQ9
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0
UBE2I-216
ENSP00000456188
ENST00000567383
P63279
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
H3BRD1
[Direct mapping] SUMO-conjugating enzyme UBC9
Show all
Metabolic proteins
Transporters
   Primary Active Transporters
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000166 [nucleotide binding]
GO:0000795 [synaptonemal complex]
GO:0001221 [transcription coregulator binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0007049 [cell cycle]
GO:0007059 [chromosome segregation]
GO:0007084 [mitotic nuclear membrane reassembly]
GO:0008134 [transcription factor binding]
GO:0016605 [PML body]
GO:0016740 [transferase activity]
GO:0016925 [protein sumoylation]
GO:0019787 [ubiquitin-like protein transferase activity]
GO:0019789 [SUMO transferase activity]
GO:0019899 [enzyme binding]
GO:0030335 [positive regulation of cell migration]
GO:0032446 [protein modification by small protein conjugation]
GO:0036211 [protein modification process]
GO:0044388 [small protein activating enzyme binding]
GO:0045892 [negative regulation of DNA-templated transcription]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051168 [nuclear export]
GO:0051301 [cell division]
GO:0061656 [SUMO conjugating enzyme activity]
GO:0071535 [RING-like zinc finger domain binding]
GO:0106068 [SUMO ligase complex]
GO:1903755 [positive regulation of SUMO transferase activity]
GO:1990234 [transferase complex]
Show all
158 aa
18 kDa
No 0

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