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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:5.9 nTPM
HPA Brain:78.7 nTPM
GTEx:5.9 nTPM
FANTOM5:86.5 Scaled Tags Per Million
Pig:45.4 nTPM
Mouse:20.4 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 67.5
1830 Male, age 51, unknown 76.3
2666 Male, age 74, left hemisphere 74.4
2019 Male, age 18, unknown 74.0
2411 Female, age 72, unknown 73.1
1833 Male, age 53, unknown 68.5
1870 Female, age 42, unknown 67.2
2828 Female, age 72, unknown 63.7
2586 Male, age 75, left hemisphere 63.3
1827 Male, age 72, unknown 58.8
2219 Male, age 76, both hemispheres 56.0
Dorsal raphe nucleus
nTPM: 50.7
2750 Male, age 76, both hemispheres 66.6
1828 Male, age 53, unknown 51.7
2047 Male, age 72, unknown 50.0
2016 Female, age 72, unknown 46.7
2298 Female, age 72, unknown 38.5
Inferior colliculus
nTPM: 52.0
1890 Male, age 53, unknown 57.4
1848 Female, age 42, unknown 52.0
2097 Female, age 72, unknown 50.6
2849 Male, age 72, unknown 48.1
Median raphe nucleus
nTPM: 51.8
2220 Male, age 76, midline 51.8
Periaquaductal grey, anterior
nTPM: 48.5
1947 Male, age 18, unknown 53.5
2502 Female, age 75, unknown 46.6
1795 Male, age 51, unknown 45.5
Periaquaductal grey, dorsal
nTPM: 41.8
2464 Female, age 72, unknown 51.9
1831 Male, age 72, unknown 46.4
2850 Male, age 76, both hemispheres 34.5
1840 Male, age 53, unknown 34.3
Periaquaductal grey, lateral
nTPM: 42.8
2053 Male, age 18, unknown 48.9
2272 Male, age 74, both hemispheres 42.6
2140 Male, age 76, both hemispheres 36.8
Pretectal area
nTPM: 50.3
2007 Male, age 72, unknown 60.9
1815 Male, age 53, unknown 59.1
2407 Male, age 75, both hemispheres 59.0
1817 Female, age 42, unknown 57.1
1944 Female, age 72, unknown 53.1
2825 Male, age 18, unknown 47.8
1816 Male, age 51, unknown 45.5
2667 Female, age 75, unknown 45.0
2316 Male, age 76, right hemisphere 44.5
2224 Female, age 72, unknown 41.0
2273 Male, age 74, both hemispheres 40.0
Red nucleus
nTPM: 78.7
2588 Male, age 74, left hemisphere 96.8
2503 Female, age 72, unknown 86.2
1865 Male, age 51, unknown 86.0
1904 Male, age 53, unknown 80.6
1821 Female, age 72, unknown 79.0
2785 Male, age 18, unknown 78.4
1954 Female, age 42, unknown 76.4
2227 Male, age 72, unknown 76.4
2769 Male, age 72, unknown 76.0
2584 Male, age 75, left hemisphere 75.2
2823 Male, age 76, right hemisphere 73.7
2725 Female, age 75, unknown 60.1
Substantia nigra
nTPM: 58.0
2583 Male, age 75, right hemisphere 70.6
2590 Female, age 75, unknown 63.9
2409 Female, age 72, unknown 63.4
1889 Female, age 72, unknown 62.0
1941 Male, age 53, unknown 59.6
1851 Male, age 51, unknown 56.7
1916 Female, age 42, unknown 56.3
2241 Male, age 72, unknown 52.5
2665 Male, age 74, both hemispheres 47.6
2699 Male, age 18, unknown 47.4
Superior colliculus
nTPM: 57.1
2668 Female, age 75, unknown 76.1
1913 Female, age 42, unknown 64.1
2587 Male, age 74, left hemisphere 63.0
1995 Male, age 72, unknown 58.4
1839 Male, age 51, unknown 56.3
1895 Male, age 76, right hemisphere 56.1
1796 Male, age 53, unknown 51.1
2261 Male, age 18, unknown 50.9
2087 Female, age 72, unknown 50.1
2664 Male, age 75, both hemispheres 44.8
Ventral tegmental area
nTPM: 57.5
2410 Female, age 72, unknown 72.2
2223 Female, age 72, unknown 68.0
1942 Male, age 51, unknown 53.8
2218 Male, age 76, both hemispheres 52.0
2021 Male, age 53, unknown 50.8
1915 Female, age 42, unknown 48.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

5.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 5.9
Samples: 139

Max nTPM: 22.1
Min nTPM: 1.6
Std nTPM: 2.3
Median nTPM: 5.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 22.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 13.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 12.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 10.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 9.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 9.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 9.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 9.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 8.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 8.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 8.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 8.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 8.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 7.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 7.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 7.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 7.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 7.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 7.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 7.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 7.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 7.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 7.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 7.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 7.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 7.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 7.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 7.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 7.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 7.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 7.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 7.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 6.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 6.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 6.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 6.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 6.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 6.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 6.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 6.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 6.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 6.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 6.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 6.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 6.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 6.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 6.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 6.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 6.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 6.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 6.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 6.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 6.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 6.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 6.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 6.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 6.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 6.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 5.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 5.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 5.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 5.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 5.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 5.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 5.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 5.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 5.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 5.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 5.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 5.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 5.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 5.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 5.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 5.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 5.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 5.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 5.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 5.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 5.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 5.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 5.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 5.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 5.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 5.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 5.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 5.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 5.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 5.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 5.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 5.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 5.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 5.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 4.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 4.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 4.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 4.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 4.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 4.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 4.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 4.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 4.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 4.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 4.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 4.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 4.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 4.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 4.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 4.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 4.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 4.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 4.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 4.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 4.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 4.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 4.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 4.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 4.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 4.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 3.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 3.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 3.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 3.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 3.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 3.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 3.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 2.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 2.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

86.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 86.5
FF:10158-103A5 76 years, female 86.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 33.6
Samples: 4

Max nTPM: 50.1
Min nTPM: 21.6
Sample A Female 29.2
Sample B Female 21.6
Sample C Male 33.5
Sample D Male 50.1
Midbrain
nTPM: 45.4
Samples: 4

Max nTPM: 75.6
Min nTPM: 31.3
Sample A Female 75.6
Sample B Female 31.3
Sample C Male 42.6
Sample D Male 32.2
Periaqueductal gray
nTPM: 25.6
Samples: 3

Max nTPM: 29.0
Min nTPM: 22.4
Sample B Female 29.0
Sample C Male 22.4
Sample D Male 25.5
Superior colliculi
nTPM: 32.9
Samples: 4

Max nTPM: 42.3
Min nTPM: 20.9
Sample A Female 26.6
Sample B Female 20.9
Sample C Male 41.6
Sample D Male 42.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 20.4
Samples: 4

Max nTPM: 23.1
Min nTPM: 15.3
Sample A Male 15.3
Sample B Male 21.1
Sample C Female 23.1
Sample D Female 22.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
69444897 Antisense, RP_050414_04_H01, Mouse strain C57BL/6J (56 days, male) 3.1

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