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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:30.7 nTPM
HPA Brain:98.8 nTPM
GTEx:30.7 nTPM
FANTOM5:111.8 Scaled Tags Per Million
Pig:102.0 nTPM
Mouse:160.9 nTPM
Allen mouse:1.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 76.9
2828 Female, age 72, unknown 102.6
2411 Female, age 72, unknown 85.0
1833 Male, age 53, unknown 82.1
2586 Male, age 75, left hemisphere 81.8
1870 Female, age 42, unknown 77.1
1830 Male, age 51, unknown 75.8
1827 Male, age 72, unknown 75.4
2219 Male, age 76, both hemispheres 66.4
2019 Male, age 18, unknown 61.6
2666 Male, age 74, left hemisphere 61.0
Dorsal raphe nucleus
nTPM: 94.8
2047 Male, age 72, unknown 107.2
2750 Male, age 76, both hemispheres 97.7
2298 Female, age 72, unknown 91.3
1828 Male, age 53, unknown 89.2
2016 Female, age 72, unknown 88.7
Inferior colliculus
nTPM: 95.9
1848 Female, age 42, unknown 108.6
1890 Male, age 53, unknown 101.8
2849 Male, age 72, unknown 87.9
2097 Female, age 72, unknown 85.4
Median raphe nucleus
nTPM: 81.5
2220 Male, age 76, midline 81.5
Periaquaductal grey, anterior
nTPM: 76.5
1947 Male, age 18, unknown 81.2
1795 Male, age 51, unknown 79.2
2502 Female, age 75, unknown 69.3
Periaquaductal grey, dorsal
nTPM: 76.0
2464 Female, age 72, unknown 87.6
1840 Male, age 53, unknown 86.9
2850 Male, age 76, both hemispheres 77.5
1831 Male, age 72, unknown 52.1
Periaquaductal grey, lateral
nTPM: 88.4
2140 Male, age 76, both hemispheres 98.0
2053 Male, age 18, unknown 95.0
2272 Male, age 74, both hemispheres 72.4
Pretectal area
nTPM: 71.3
2316 Male, age 76, right hemisphere 85.2
2825 Male, age 18, unknown 84.8
2667 Female, age 75, unknown 82.3
1944 Female, age 72, unknown 76.7
2224 Female, age 72, unknown 76.6
2273 Male, age 74, both hemispheres 71.4
1817 Female, age 42, unknown 71.0
1816 Male, age 51, unknown 60.8
2007 Male, age 72, unknown 60.4
2407 Male, age 75, both hemispheres 58.1
1815 Male, age 53, unknown 57.1
Red nucleus
nTPM: 98.8
2227 Male, age 72, unknown 134.6
2769 Male, age 72, unknown 128.2
1865 Male, age 51, unknown 112.4
2725 Female, age 75, unknown 110.6
2503 Female, age 72, unknown 107.6
1954 Female, age 42, unknown 105.2
1821 Female, age 72, unknown 100.6
2823 Male, age 76, right hemisphere 99.3
1904 Male, age 53, unknown 88.9
2588 Male, age 74, left hemisphere 72.3
2584 Male, age 75, left hemisphere 66.3
2785 Male, age 18, unknown 59.4
Substantia nigra
nTPM: 87.8
2699 Male, age 18, unknown 114.8
1916 Female, age 42, unknown 104.6
2409 Female, age 72, unknown 94.8
1851 Male, age 51, unknown 85.9
1941 Male, age 53, unknown 85.0
1889 Female, age 72, unknown 84.8
2241 Male, age 72, unknown 77.6
2590 Female, age 75, unknown 77.5
2583 Male, age 75, right hemisphere 76.8
2665 Male, age 74, both hemispheres 75.9
Superior colliculus
nTPM: 67.8
1796 Male, age 53, unknown 81.6
2087 Female, age 72, unknown 77.6
1895 Male, age 76, right hemisphere 77.4
2261 Male, age 18, unknown 73.2
1839 Male, age 51, unknown 69.3
1995 Male, age 72, unknown 64.6
2668 Female, age 75, unknown 61.9
2587 Male, age 74, left hemisphere 60.2
1913 Female, age 42, unknown 59.0
2664 Male, age 75, both hemispheres 52.8
Ventral tegmental area
nTPM: 87.0
2223 Female, age 72, unknown 106.3
2410 Female, age 72, unknown 88.1
2218 Male, age 76, both hemispheres 84.9
1915 Female, age 42, unknown 84.5
1942 Male, age 51, unknown 81.3
2021 Male, age 53, unknown 76.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 30.7
Samples: 139

Max nTPM: 80.4
Min nTPM: 4.0
Std nTPM: 16.2
Median nTPM: 26.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 80.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 79.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 75.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 67.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 66.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 64.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 64.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 62.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 60.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 58.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 57.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 56.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 55.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 54.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 52.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 51.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 51.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 50.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 49.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 48.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 47.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 45.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 44.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 44.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 43.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 43.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 43.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 43.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 42.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 42.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 41.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 39.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 38.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 37.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 37.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 37.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 37.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 37.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 36.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 36.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 36.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 35.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 35.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 34.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 34.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 34.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 33.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 33.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 32.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 31.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 31.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 30.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 30.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 30.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 29.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 29.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 29.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 29.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 28.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 28.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 28.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 27.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 26.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 26.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 26.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 26.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 26.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 26.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 26.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 25.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 25.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 24.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 24.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 24.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 24.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 24.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 23.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 23.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 23.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 23.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 23.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 22.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 22.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 22.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 21.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 21.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 21.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 21.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 20.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 20.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 20.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 20.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 20.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 19.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 19.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 19.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 19.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 19.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 18.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 18.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 18.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 17.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 17.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 16.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 16.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 16.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 16.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 16.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 16.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 15.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 15.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 15.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 15.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 15.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 14.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 14.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 14.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 12.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 12.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 12.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 12.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 11.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 11.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 10.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 10.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 9.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 9.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 8.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 6.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 6.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 4.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 4.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

111.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 111.8
FF:10158-103A5 76 years, female 111.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

102.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 98.5
Samples: 4

Max nTPM: 132.0
Min nTPM: 72.0
Sample A Female 100.5
Sample B Female 72.0
Sample C Male 89.3
Sample D Male 132.0
Midbrain
nTPM: 102.0
Samples: 4

Max nTPM: 109.8
Min nTPM: 98.3
Sample A Female 109.8
Sample B Female 100.0
Sample C Male 98.3
Sample D Male 99.8
Periaqueductal gray
nTPM: 92.9
Samples: 3

Max nTPM: 105.6
Min nTPM: 83.4
Sample B Female 105.6
Sample C Male 89.6
Sample D Male 83.4
Superior colliculi
nTPM: 99.1
Samples: 4

Max nTPM: 124.5
Min nTPM: 57.6
Sample A Female 124.5
Sample B Female 57.6
Sample C Male 97.9
Sample D Male 116.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

160.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 160.9
Samples: 4

Max nTPM: 180.7
Min nTPM: 148.1
Sample A Male 180.7
Sample B Male 151.4
Sample C Female 148.1
Sample D Female 163.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.1
370 Antisense, RP_Baylor_103313, Mouse strain C57BL/6J (56 days, male) 1.1
369 Antisense, RP_Baylor_103313, Mouse strain C57BL/6J (56 days, male) 0.3

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