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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:103.7 nTPM
HPA Brain:170.9 nTPM
GTEx:103.7 nTPM
FANTOM5:106.0 Scaled Tags Per Million
Pig:136.7 nTPM
Mouse:42.6 nTPM
Allen mouse:8.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

170.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 150.3
2586 Male, age 75, left hemisphere 218.4
2666 Male, age 74, left hemisphere 191.8
2828 Female, age 72, unknown 159.6
2219 Male, age 76, both hemispheres 151.7
1827 Male, age 72, unknown 143.6
1870 Female, age 42, unknown 139.5
1833 Male, age 53, unknown 134.6
2019 Male, age 18, unknown 125.9
2411 Female, age 72, unknown 120.2
1830 Male, age 51, unknown 117.7
Dorsal raphe nucleus
nTPM: 136.4
2047 Male, age 72, unknown 154.7
2750 Male, age 76, both hemispheres 142.4
1828 Male, age 53, unknown 137.0
2298 Female, age 72, unknown 133.5
2016 Female, age 72, unknown 114.3
Inferior colliculus
nTPM: 121.8
2849 Male, age 72, unknown 137.6
1848 Female, age 42, unknown 125.9
1890 Male, age 53, unknown 119.1
2097 Female, age 72, unknown 104.8
Median raphe nucleus
nTPM: 170.9
2220 Male, age 76, midline 170.9
Periaquaductal grey, anterior
nTPM: 145.1
1947 Male, age 18, unknown 165.6
1795 Male, age 51, unknown 152.1
2502 Female, age 75, unknown 117.5
Periaquaductal grey, dorsal
nTPM: 117.6
1840 Male, age 53, unknown 128.6
1831 Male, age 72, unknown 121.0
2850 Male, age 76, both hemispheres 120.1
2464 Female, age 72, unknown 100.6
Periaquaductal grey, lateral
nTPM: 106.1
2053 Male, age 18, unknown 116.9
2272 Male, age 74, both hemispheres 105.5
2140 Male, age 76, both hemispheres 95.8
Pretectal area
nTPM: 147.3
1816 Male, age 51, unknown 191.0
1944 Female, age 72, unknown 182.7
1817 Female, age 42, unknown 181.6
2007 Male, age 72, unknown 166.2
2667 Female, age 75, unknown 165.4
1815 Male, age 53, unknown 159.6
2407 Male, age 75, both hemispheres 135.5
2825 Male, age 18, unknown 131.4
2224 Female, age 72, unknown 118.5
2316 Male, age 76, right hemisphere 97.0
2273 Male, age 74, both hemispheres 92.0
Red nucleus
nTPM: 132.4
2584 Male, age 75, left hemisphere 179.1
2588 Male, age 74, left hemisphere 144.5
2725 Female, age 75, unknown 139.5
1821 Female, age 72, unknown 136.9
1904 Male, age 53, unknown 128.7
2785 Male, age 18, unknown 127.7
1954 Female, age 42, unknown 127.2
1865 Male, age 51, unknown 122.8
2227 Male, age 72, unknown 121.8
2769 Male, age 72, unknown 121.4
2503 Female, age 72, unknown 120.9
2823 Male, age 76, right hemisphere 118.8
Substantia nigra
nTPM: 147.1
2665 Male, age 74, both hemispheres 192.6
1916 Female, age 42, unknown 184.7
1889 Female, age 72, unknown 161.7
1851 Male, age 51, unknown 158.3
2583 Male, age 75, right hemisphere 153.3
1941 Male, age 53, unknown 143.6
2699 Male, age 18, unknown 142.7
2241 Male, age 72, unknown 132.4
2590 Female, age 75, unknown 114.5
2409 Female, age 72, unknown 86.8
Superior colliculus
nTPM: 144.9
2668 Female, age 75, unknown 180.1
2664 Male, age 75, both hemispheres 175.7
2087 Female, age 72, unknown 158.9
1796 Male, age 53, unknown 151.2
2261 Male, age 18, unknown 149.4
1913 Female, age 42, unknown 133.1
2587 Male, age 74, left hemisphere 128.9
1839 Male, age 51, unknown 125.6
1895 Male, age 76, right hemisphere 125.4
1995 Male, age 72, unknown 121.0
Ventral tegmental area
nTPM: 138.6
2218 Male, age 76, both hemispheres 158.7
1915 Female, age 42, unknown 149.6
2223 Female, age 72, unknown 137.3
1942 Male, age 51, unknown 136.3
2410 Female, age 72, unknown 128.6
2021 Male, age 53, unknown 121.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

103.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 103.7
Samples: 139

Max nTPM: 167.1
Min nTPM: 45.1
Std nTPM: 24.7
Median nTPM: 102.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 167.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 166.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 162.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 162.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 158.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 153.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 150.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 148.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 146.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 141.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 141.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 140.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 140.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 137.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 135.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 133.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 131.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 131.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 130.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 128.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 128.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 128.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 127.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 126.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 126.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 126.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 125.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 124.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 123.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 122.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 122.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 122.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 120.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 119.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 119.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 118.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 118.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 117.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 116.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 114.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 114.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 113.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 113.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 113.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 112.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 112.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 112.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 111.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 111.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 111.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 110.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 110.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 110.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 109.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 109.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 109.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 108.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 107.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 107.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 106.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 106.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 106.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 106.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 105.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 105.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 104.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 104.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 104.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 103.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 102.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 102.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 101.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 100.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 100.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 98.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 98.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 98.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 98.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 98.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 97.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 97.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 97.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 96.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 95.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 95.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 95.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 95.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 94.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 94.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 93.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 93.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 92.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 91.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 91.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 90.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 90.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 89.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 88.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 87.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 87.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 87.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 87.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 86.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 86.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 86.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 85.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 85.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 85.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 84.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 84.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 84.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 82.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 81.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 81.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 80.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 77.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 75.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 75.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 74.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 74.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 73.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 72.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 71.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 71.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 70.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 68.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 66.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 64.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 64.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 63.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 63.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 58.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 54.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 53.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 45.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

106.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 106.0
FF:10158-103A5 76 years, female 106.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

136.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 125.8
Samples: 4

Max nTPM: 142.3
Min nTPM: 94.0
Sample A Female 140.5
Sample B Female 94.0
Sample C Male 142.3
Sample D Male 126.2
Midbrain
nTPM: 136.7
Samples: 4

Max nTPM: 170.7
Min nTPM: 101.3
Sample A Female 156.5
Sample B Female 101.3
Sample C Male 170.7
Sample D Male 118.2
Periaqueductal gray
nTPM: 96.2
Samples: 3

Max nTPM: 105.7
Min nTPM: 88.9
Sample B Female 93.9
Sample C Male 105.7
Sample D Male 88.9
Superior colliculi
nTPM: 134.4
Samples: 4

Max nTPM: 158.4
Min nTPM: 101.1
Sample A Female 142.4
Sample B Female 101.1
Sample C Male 158.4
Sample D Male 135.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 42.6
Samples: 4

Max nTPM: 45.2
Min nTPM: 40.0
Sample A Male 40.0
Sample B Male 42.2
Sample C Female 45.2
Sample D Female 43.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.6
71608394 Antisense, RP_050927_01_F11, Mouse strain C57BL/6J (56 days, male) 11.8
544901 Antisense, RP_040617_02_G04, Mouse strain C57BL/6J (56 days, male) 5.5

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