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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:252.8 nTPM
HPA Brain:117.5 nTPM
GTEx:252.8 nTPM
FANTOM5:310.4 Scaled Tags Per Million
Pig:345.7 nTPM
Mouse:392.8 nTPM
Allen mouse:15.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

117.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 85.4
2586 Male, age 75, left hemisphere 99.6
2019 Male, age 18, unknown 95.3
2666 Male, age 74, left hemisphere 95.0
2219 Male, age 76, both hemispheres 92.7
1827 Male, age 72, unknown 89.9
1870 Female, age 42, unknown 89.6
2411 Female, age 72, unknown 88.4
1833 Male, age 53, unknown 69.5
2828 Female, age 72, unknown 66.9
1830 Male, age 51, unknown 66.8
Dorsal raphe nucleus
nTPM: 89.3
2298 Female, age 72, unknown 107.5
2047 Male, age 72, unknown 93.8
1828 Male, age 53, unknown 88.5
2750 Male, age 76, both hemispheres 84.5
2016 Female, age 72, unknown 72.2
Inferior colliculus
nTPM: 83.2
2097 Female, age 72, unknown 103.1
1890 Male, age 53, unknown 80.0
1848 Female, age 42, unknown 78.4
2849 Male, age 72, unknown 71.4
Median raphe nucleus
nTPM: 95.1
2220 Male, age 76, midline 95.1
Periaquaductal grey, anterior
nTPM: 96.6
2502 Female, age 75, unknown 97.7
1947 Male, age 18, unknown 96.8
1795 Male, age 51, unknown 95.2
Periaquaductal grey, dorsal
nTPM: 84.4
1840 Male, age 53, unknown 100.1
1831 Male, age 72, unknown 82.5
2464 Female, age 72, unknown 77.6
2850 Male, age 76, both hemispheres 77.3
Periaquaductal grey, lateral
nTPM: 66.5
2272 Male, age 74, both hemispheres 74.6
2053 Male, age 18, unknown 73.5
2140 Male, age 76, both hemispheres 51.3
Pretectal area
nTPM: 92.6
1816 Male, age 51, unknown 124.4
1944 Female, age 72, unknown 120.1
2007 Male, age 72, unknown 118.2
1817 Female, age 42, unknown 103.9
2667 Female, age 75, unknown 95.8
1815 Male, age 53, unknown 91.4
2224 Female, age 72, unknown 90.7
2407 Male, age 75, both hemispheres 72.2
2273 Male, age 74, both hemispheres 68.9
2316 Male, age 76, right hemisphere 66.7
2825 Male, age 18, unknown 66.4
Red nucleus
nTPM: 75.3
1821 Female, age 72, unknown 100.0
2785 Male, age 18, unknown 86.1
1954 Female, age 42, unknown 82.5
2725 Female, age 75, unknown 82.1
1904 Male, age 53, unknown 79.6
2584 Male, age 75, left hemisphere 73.0
2769 Male, age 72, unknown 69.7
2227 Male, age 72, unknown 68.9
2503 Female, age 72, unknown 68.4
2588 Male, age 74, left hemisphere 67.0
2823 Male, age 76, right hemisphere 63.9
1865 Male, age 51, unknown 62.8
Substantia nigra
nTPM: 117.5
1916 Female, age 42, unknown 151.1
1851 Male, age 51, unknown 136.3
1941 Male, age 53, unknown 128.2
1889 Female, age 72, unknown 125.4
2241 Male, age 72, unknown 121.4
2665 Male, age 74, both hemispheres 119.9
2699 Male, age 18, unknown 109.4
2409 Female, age 72, unknown 107.5
2583 Male, age 75, right hemisphere 95.0
2590 Female, age 75, unknown 80.7
Superior colliculus
nTPM: 85.9
2668 Female, age 75, unknown 103.6
2087 Female, age 72, unknown 98.0
2664 Male, age 75, both hemispheres 97.7
1895 Male, age 76, right hemisphere 87.9
1796 Male, age 53, unknown 84.1
2261 Male, age 18, unknown 84.0
2587 Male, age 74, left hemisphere 78.3
1839 Male, age 51, unknown 76.3
1995 Male, age 72, unknown 75.0
1913 Female, age 42, unknown 73.9
Ventral tegmental area
nTPM: 97.5
1915 Female, age 42, unknown 109.2
2410 Female, age 72, unknown 108.3
1942 Male, age 51, unknown 101.7
2218 Male, age 76, both hemispheres 96.4
2021 Male, age 53, unknown 86.5
2223 Female, age 72, unknown 83.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

252.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 252.8
Samples: 139

Max nTPM: 456.6
Min nTPM: 105.6
Std nTPM: 71.6
Median nTPM: 242.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 456.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 439.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 439.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 433.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 431.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 411.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 407.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 386.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 384.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 383.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 382.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 382.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 343.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 340.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 337.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 328.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 327.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 327.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 326.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 320.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 317.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 316.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 315.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 315.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 315.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 314.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 311.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 310.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 308.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 308.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 304.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 302.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 301.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 297.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 294.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 293.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 293.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 290.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 287.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 287.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 285.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 285.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 284.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 279.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 276.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 275.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 274.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 274.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 273.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 271.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 271.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 270.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 266.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 264.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 264.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 260.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 259.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 257.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 256.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 256.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 252.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 252.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 249.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 245.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 245.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 244.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 243.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 243.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 242.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 242.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 242.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 241.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 241.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 240.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 239.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 237.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 235.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 235.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 234.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 233.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 232.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 229.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 229.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 228.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 223.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 223.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 223.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 220.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 220.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 219.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 218.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 218.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 214.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 213.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 212.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 211.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 211.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 211.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 210.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 210.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 208.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 207.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 207.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 205.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 205.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 204.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 204.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 202.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 199.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 199.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 197.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 197.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 193.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 192.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 190.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 190.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 188.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 186.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 184.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 182.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 181.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 181.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 175.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 172.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 170.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 160.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 160.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 158.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 156.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 156.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 154.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 150.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 145.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 144.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 143.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 126.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 123.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 121.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 105.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

310.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 310.4
FF:10158-103A5 76 years, female 310.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

345.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 340.1
Samples: 4

Max nTPM: 475.6
Min nTPM: 222.9
Sample A Female 475.6
Sample B Female 314.2
Sample C Male 347.6
Sample D Male 222.9
Midbrain
nTPM: 335.3
Samples: 4

Max nTPM: 415.9
Min nTPM: 300.6
Sample A Female 415.9
Sample B Female 306.3
Sample C Male 318.2
Sample D Male 300.6
Periaqueductal gray
nTPM: 254.0
Samples: 3

Max nTPM: 289.6
Min nTPM: 221.2
Sample B Female 251.1
Sample C Male 289.6
Sample D Male 221.2
Superior colliculi
nTPM: 345.7
Samples: 4

Max nTPM: 423.1
Min nTPM: 283.1
Sample A Female 423.1
Sample B Female 352.1
Sample C Male 324.6
Sample D Male 283.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

392.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 392.8
Samples: 4

Max nTPM: 468.2
Min nTPM: 330.4
Sample A Male 468.2
Sample B Male 364.2
Sample C Female 330.4
Sample D Female 408.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.1
69782533 Antisense, RP_050505_03_B12, Mouse strain C57BL/6J (56 days, male) 15.1

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