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STX10
HPA
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  • SUMMARY

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  • STX10
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

STX10
Synonyms hsyn10, SYN10
Gene descriptioni

Full gene name according to HGNC.

Syntaxin 10
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Membrane, Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 19
Cytoband p13.13
Chromosome location (bp) 13144058 - 13150383
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

9
Ensembl ENSG00000104915 (version 109)
Entrez gene 8677
HGNC HGNC:11428
UniProt O60499 (UniProt - Evidence at protein level)
neXtProt NX_O60499
GeneCards STX10
Antibodypedia STX10 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.... show less
Biological process (UniProt)i

Keywords assigned by UniProt to proteins because they are involved in a particular biological process.

Protein transport, Transport
Gene summary (Entrez)i

Useful information about the gene from Entrez

This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
STX10-201
ENSP00000242770
ENST00000242770
X6R2W0
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005794 [Golgi apparatus]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0048193 [Golgi vesicle transport]
Show all
220 aa
24.9 kDa
No 0
STX10-202
ENSP00000339350
ENST00000343587
O60499
[Direct mapping] Syntaxin-10
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
   DeepTMHMM predicted membrane proteins
Show all
GO:0000139 [Golgi membrane]
GO:0000149 [SNARE binding]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0012505 [endomembrane system]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019905 [syntaxin binding]
GO:0030672 [synaptic vesicle membrane]
GO:0031201 [SNARE complex]
GO:0031982 [vesicle]
GO:0032588 [trans-Golgi network membrane]
GO:0032880 [regulation of protein localization]
GO:0042147 [retrograde transport, endosome to Golgi]
GO:0048193 [Golgi vesicle transport]
GO:0048278 [vesicle docking]
GO:0048471 [perinuclear region of cytoplasm]
Show all
200 aa
22.4 kDa
No 1
STX10-204
ENSP00000466298
ENST00000587230
O60499
[Direct mapping] Syntaxin-10
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
   DeepTMHMM predicted membrane proteins
Show all
GO:0000139 [Golgi membrane]
GO:0000149 [SNARE binding]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0012505 [endomembrane system]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019905 [syntaxin binding]
GO:0030672 [synaptic vesicle membrane]
GO:0031201 [SNARE complex]
GO:0031982 [vesicle]
GO:0032588 [trans-Golgi network membrane]
GO:0032880 [regulation of protein localization]
GO:0042147 [retrograde transport, endosome to Golgi]
GO:0048193 [Golgi vesicle transport]
GO:0048278 [vesicle docking]
GO:0048471 [perinuclear region of cytoplasm]
Show all
249 aa
28.1 kDa
No 1
STX10-205
ENSP00000464943
ENST00000587318
K7EIY4
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005484 [SNAP receptor activity]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0048193 [Golgi vesicle transport]
GO:0061025 [membrane fusion]
Show all
228 aa
25.5 kDa
No 0
STX10-206
ENSP00000467479
ENST00000588848
K7EPP9
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0006886 [intracellular protein transport]
GO:0016020 [membrane]
GO:0061025 [membrane fusion]
Show all
122 aa
13.6 kDa
No 0
STX10-207
ENSP00000465398
ENST00000589083
Q5U8S2
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005484 [SNAP receptor activity]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0048193 [Golgi vesicle transport]
GO:0061025 [membrane fusion]
Show all
246 aa
27.6 kDa
No 0
STX10-208
ENSP00000464970
ENST00000591197
K7EJ05
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
58 aa
6.4 kDa
No 0
STX10-209
ENSP00000467713
ENST00000591415
K7EQ84
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0006886 [intracellular protein transport]
GO:0016020 [membrane]
GO:0061025 [membrane fusion]
Show all
97 aa
10.5 kDa
No 0
STX10-211
ENSP00000466272
ENST00000593126
K7ELY2
[Direct mapping] Syntaxin-10
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005484 [SNAP receptor activity]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0048193 [Golgi vesicle transport]
GO:0061025 [membrane fusion]
Show all
201 aa
22.5 kDa
No 0

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