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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:69.9 nTPM
HPA Brain:62.6 nTPM
GTEx:69.9 nTPM
FANTOM5:68.7 Scaled Tags Per Million
Pig:56.7 nTPM
Mouse:72.3 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.8
2586 Male, age 75, left hemisphere 88.4
1870 Female, age 42, unknown 60.1
1830 Male, age 51, unknown 59.1
2828 Female, age 72, unknown 57.7
1833 Male, age 53, unknown 57.1
2019 Male, age 18, unknown 56.3
2666 Male, age 74, left hemisphere 54.2
1827 Male, age 72, unknown 52.3
2411 Female, age 72, unknown 52.0
2219 Male, age 76, both hemispheres 41.0
Dorsal raphe nucleus
nTPM: 46.7
2750 Male, age 76, both hemispheres 55.8
2047 Male, age 72, unknown 47.1
1828 Male, age 53, unknown 45.1
2016 Female, age 72, unknown 44.6
2298 Female, age 72, unknown 41.0
Inferior colliculus
nTPM: 44.8
1890 Male, age 53, unknown 48.0
1848 Female, age 42, unknown 47.8
2849 Male, age 72, unknown 42.9
2097 Female, age 72, unknown 40.6
Median raphe nucleus
nTPM: 48.8
2220 Male, age 76, midline 48.8
Periaquaductal grey, anterior
nTPM: 52.4
2502 Female, age 75, unknown 55.6
1947 Male, age 18, unknown 51.6
1795 Male, age 51, unknown 50.0
Periaquaductal grey, dorsal
nTPM: 43.0
1831 Male, age 72, unknown 45.5
1840 Male, age 53, unknown 43.1
2850 Male, age 76, both hemispheres 42.6
2464 Female, age 72, unknown 40.7
Periaquaductal grey, lateral
nTPM: 43.7
2053 Male, age 18, unknown 48.3
2140 Male, age 76, both hemispheres 42.8
2272 Male, age 74, both hemispheres 40.1
Pretectal area
nTPM: 52.3
2007 Male, age 72, unknown 61.1
1817 Female, age 42, unknown 60.1
1815 Male, age 53, unknown 58.6
2407 Male, age 75, both hemispheres 56.7
1944 Female, age 72, unknown 53.8
1816 Male, age 51, unknown 53.0
2825 Male, age 18, unknown 52.9
2667 Female, age 75, unknown 51.0
2316 Male, age 76, right hemisphere 44.7
2224 Female, age 72, unknown 42.6
2273 Male, age 74, both hemispheres 40.5
Red nucleus
nTPM: 62.6
2584 Male, age 75, left hemisphere 73.7
1865 Male, age 51, unknown 69.2
1904 Male, age 53, unknown 67.2
2588 Male, age 74, left hemisphere 63.0
2227 Male, age 72, unknown 61.8
2503 Female, age 72, unknown 61.5
2769 Male, age 72, unknown 60.4
2785 Male, age 18, unknown 60.2
2725 Female, age 75, unknown 59.4
2823 Male, age 76, right hemisphere 59.1
1954 Female, age 42, unknown 59.0
1821 Female, age 72, unknown 56.8
Substantia nigra
nTPM: 55.8
2583 Male, age 75, right hemisphere 68.1
1851 Male, age 51, unknown 60.7
1916 Female, age 42, unknown 60.7
1889 Female, age 72, unknown 60.2
2665 Male, age 74, both hemispheres 55.5
2699 Male, age 18, unknown 54.4
2409 Female, age 72, unknown 52.5
1941 Male, age 53, unknown 50.6
2590 Female, age 75, unknown 49.7
2241 Male, age 72, unknown 45.9
Superior colliculus
nTPM: 57.2
2664 Male, age 75, both hemispheres 70.4
1913 Female, age 42, unknown 64.6
1995 Male, age 72, unknown 64.1
2668 Female, age 75, unknown 63.7
2261 Male, age 18, unknown 54.4
2587 Male, age 74, left hemisphere 53.7
1796 Male, age 53, unknown 53.6
1895 Male, age 76, right hemisphere 49.5
2087 Female, age 72, unknown 49.5
1839 Male, age 51, unknown 48.3
Ventral tegmental area
nTPM: 56.2
2223 Female, age 72, unknown 63.1
2410 Female, age 72, unknown 58.9
1915 Female, age 42, unknown 57.3
2218 Male, age 76, both hemispheres 53.9
1942 Male, age 51, unknown 53.4
2021 Male, age 53, unknown 50.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

69.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 69.9
Samples: 139

Max nTPM: 170.0
Min nTPM: 33.3
Std nTPM: 18.6
Median nTPM: 67.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 170.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 145.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 122.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 122.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 105.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 102.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 101.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 99.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 99.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 97.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 93.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 90.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 88.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 88.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 88.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 88.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 87.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 87.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 85.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 85.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 85.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 84.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 84.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 84.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 84.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 84.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 83.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 82.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 82.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 81.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 81.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 80.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 80.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 80.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 77.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 77.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 77.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 76.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 76.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 76.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 75.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 74.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 74.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 73.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 73.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 73.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 72.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 71.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 71.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 70.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 70.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 70.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 70.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 70.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 69.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 69.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 68.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 68.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 68.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 68.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 68.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 68.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 68.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 67.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 67.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 67.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 67.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 67.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 66.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 66.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 65.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 65.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 65.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 64.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 64.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 64.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 64.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 63.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 63.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 63.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 62.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 62.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 62.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 62.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 61.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 61.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 61.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 61.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 61.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 61.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 61.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 60.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 60.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 59.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 59.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 59.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 58.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 58.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 58.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 58.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 58.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 58.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 58.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 56.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 56.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 56.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 55.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 55.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 55.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 55.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 55.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 54.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 53.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 53.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 53.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 52.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 52.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 52.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 52.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 51.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 51.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 51.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 50.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 49.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 48.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 48.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 48.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 48.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 48.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 46.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 45.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 43.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 41.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 33.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

68.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 68.7
FF:10158-103A5 76 years, female 68.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

56.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 48.3
Samples: 4

Max nTPM: 56.2
Min nTPM: 40.6
Sample A Female 56.2
Sample B Female 40.6
Sample C Male 51.1
Sample D Male 45.4
Midbrain
nTPM: 56.8
Samples: 4

Max nTPM: 73.3
Min nTPM: 44.3
Sample A Female 73.3
Sample B Female 44.3
Sample C Male 60.6
Sample D Male 48.8
Periaqueductal gray
nTPM: 41.3
Samples: 3

Max nTPM: 44.5
Min nTPM: 39.5
Sample B Female 39.5
Sample C Male 44.5
Sample D Male 40.0
Superior colliculi
nTPM: 56.2
Samples: 4

Max nTPM: 61.7
Min nTPM: 49.1
Sample A Female 58.6
Sample B Female 49.1
Sample C Male 61.7
Sample D Male 55.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 72.3
Samples: 4

Max nTPM: 80.7
Min nTPM: 66.1
Sample A Male 80.7
Sample B Male 67.8
Sample C Female 66.1
Sample D Female 74.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
68076557 Antisense, RP_040923_02_G06, Mouse strain C57BL/6J (56 days, male) 0.5

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