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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Cancer-related genes Disease related genes Enzymes Human disease related genes Potential drug targets RAS pathway related proteins
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
19
Cytoband
q13.2
Chromosome location (bp)
40230317 - 40285536
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Serine/threonine kinase closely related to AKT1 and AKT3. All 3 enzymes, AKT1, AKT2 and AKT3, are collectively known as AKT kinase. AKT regulates many processes including metabolism, proliferation, cell survival, growth and angiogenesis, through the phosphorylation of a range of downstream substrates. Over 100 substrates have been reported so far, although for most of them, the precise AKT kinase catalyzing the reaction was not specified. AKT regulates glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for insulin-stimulated glucose transport. AKT also regulates the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven. AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stimulated by oxidative stress and thereby prevents apoptosis. AKT mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In particular, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the regulation of NF-kappa-B-dependent gene transcription and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially regulating ACLY activity and fatty acid synthesis. Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which results in increased PI(3)P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the regulation cell proliferation and cell growth. AKT plays a role as key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. May be involved in the regulation of the placental development 1,2. In response to lysophosphatidic acid stimulation, inhibits the ciliogenesis cascade. In this context, phosphorylates WDR44, hence stabilizing its interaction with Rab11 and preventing the formation of the ciliogenic Rab11-FIP3-RAB3IP complex. Also phosphorylates RAB3IP/Rabin8, thus may affect RAB3IP guanine nucleotide exchange factor (GEF) activity toward Rab8, which is important for cilia growth 3....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling. [provided by RefSeq, Nov 2019]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Enzymes ENZYME proteins Transferases Kinases AGC Ser/Thr protein kinases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Disease related genes Potential drug targets Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000166[nucleotide binding] GO:0001934[positive regulation of protein phosphorylation] GO:0004672[protein kinase activity] GO:0004674[protein serine/threonine kinase activity] GO:0005515[protein binding] GO:0005524[ATP binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005768[endosome] GO:0005769[early endosome] GO:0005829[cytosol] GO:0005886[plasma membrane] GO:0005938[cell cortex] GO:0005975[carbohydrate metabolic process] GO:0005977[glycogen metabolic process] GO:0005978[glycogen biosynthetic process] GO:0006006[glucose metabolic process] GO:0006417[regulation of translation] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0007165[signal transduction] GO:0008284[positive regulation of cell population proliferation] GO:0008286[insulin receptor signaling pathway] GO:0008643[carbohydrate transport] GO:0010748[negative regulation of long-chain fatty acid import across plasma membrane] GO:0010907[positive regulation of glucose metabolic process] GO:0010918[positive regulation of mitochondrial membrane potential] GO:0016020[membrane] GO:0016301[kinase activity] GO:0016310[phosphorylation] GO:0016740[transferase activity] GO:0018105[peptidyl-serine phosphorylation] GO:0030334[regulation of cell migration] GO:0030335[positive regulation of cell migration] GO:0031340[positive regulation of vesicle fusion] GO:0032000[positive regulation of fatty acid beta-oxidation] GO:0032587[ruffle membrane] GO:0032869[cellular response to insulin stimulus] GO:0032991[protein-containing complex] GO:0035556[intracellular signal transduction] GO:0036211[protein modification process] GO:0043066[negative regulation of apoptotic process] GO:0043231[intracellular membrane-bounded organelle] GO:0045444[fat cell differentiation] GO:0045725[positive regulation of glycogen biosynthetic process] GO:0046326[positive regulation of glucose import] GO:0046872[metal ion binding] GO:0051726[regulation of cell cycle] GO:0060644[mammary gland epithelial cell differentiation] GO:0065002[intracellular protein transmembrane transport] GO:0090314[positive regulation of protein targeting to membrane] GO:0106310[protein serine kinase activity] GO:0140677[molecular function activator activity] GO:2000147[positive regulation of cell motility]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
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GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Enzymes ENZYME proteins Transferases Kinases AGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Disease related genes Potential drug targets Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166[nucleotide binding] GO:0001934[positive regulation of protein phosphorylation] GO:0004672[protein kinase activity] GO:0004674[protein serine/threonine kinase activity] GO:0005515[protein binding] GO:0005524[ATP binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005768[endosome] GO:0005769[early endosome] GO:0005829[cytosol] GO:0005886[plasma membrane] GO:0005938[cell cortex] GO:0005975[carbohydrate metabolic process] GO:0005977[glycogen metabolic process] GO:0005978[glycogen biosynthetic process] GO:0006006[glucose metabolic process] GO:0006417[regulation of translation] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0007165[signal transduction] GO:0008284[positive regulation of cell population proliferation] GO:0008286[insulin receptor signaling pathway] GO:0008643[carbohydrate transport] GO:0010748[negative regulation of long-chain fatty acid import across plasma membrane] GO:0010907[positive regulation of glucose metabolic process] GO:0010918[positive regulation of mitochondrial membrane potential] GO:0016020[membrane] GO:0016301[kinase activity] GO:0016310[phosphorylation] GO:0016740[transferase activity] GO:0018105[peptidyl-serine phosphorylation] GO:0030334[regulation of cell migration] GO:0030335[positive regulation of cell migration] GO:0031340[positive regulation of vesicle fusion] GO:0032000[positive regulation of fatty acid beta-oxidation] GO:0032287[peripheral nervous system myelin maintenance] GO:0032587[ruffle membrane] GO:0032869[cellular response to insulin stimulus] GO:0032991[protein-containing complex] GO:0035556[intracellular signal transduction] GO:0036211[protein modification process] GO:0043066[negative regulation of apoptotic process] GO:0043231[intracellular membrane-bounded organelle] GO:0045444[fat cell differentiation] GO:0045725[positive regulation of glycogen biosynthetic process] GO:0046326[positive regulation of glucose import] GO:0046872[metal ion binding] GO:0051726[regulation of cell cycle] GO:0060644[mammary gland epithelial cell differentiation] GO:0065002[intracellular protein transmembrane transport] GO:0071486[cellular response to high light intensity] GO:0072659[protein localization to plasma membrane] GO:0090314[positive regulation of protein targeting to membrane] GO:0090630[activation of GTPase activity] GO:0097473[retinal rod cell apoptotic process] GO:0106310[protein serine kinase activity] GO:0140677[molecular function activator activity] GO:2000147[positive regulation of cell motility]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Enzymes ENZYME proteins Transferases Kinases AGC Ser/Thr protein kinases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Disease related genes Potential drug targets Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166[nucleotide binding] GO:0001934[positive regulation of protein phosphorylation] GO:0004672[protein kinase activity] GO:0004674[protein serine/threonine kinase activity] GO:0005515[protein binding] GO:0005524[ATP binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005768[endosome] GO:0005769[early endosome] GO:0005829[cytosol] GO:0005886[plasma membrane] GO:0005938[cell cortex] GO:0005975[carbohydrate metabolic process] GO:0005977[glycogen metabolic process] GO:0005978[glycogen biosynthetic process] GO:0006006[glucose metabolic process] GO:0006417[regulation of translation] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0007165[signal transduction] GO:0008284[positive regulation of cell population proliferation] GO:0008286[insulin receptor signaling pathway] GO:0008643[carbohydrate transport] GO:0010748[negative regulation of long-chain fatty acid import across plasma membrane] GO:0010907[positive regulation of glucose metabolic process] GO:0010918[positive regulation of mitochondrial membrane potential] GO:0016020[membrane] GO:0016301[kinase activity] GO:0016310[phosphorylation] GO:0016740[transferase activity] GO:0018105[peptidyl-serine phosphorylation] GO:0030334[regulation of cell migration] GO:0030335[positive regulation of cell migration] GO:0031340[positive regulation of vesicle fusion] GO:0032000[positive regulation of fatty acid beta-oxidation] GO:0032587[ruffle membrane] GO:0032869[cellular response to insulin stimulus] GO:0032991[protein-containing complex] GO:0035556[intracellular signal transduction] GO:0036211[protein modification process] GO:0043066[negative regulation of apoptotic process] GO:0043231[intracellular membrane-bounded organelle] GO:0045444[fat cell differentiation] GO:0045725[positive regulation of glycogen biosynthetic process] GO:0046326[positive regulation of glucose import] GO:0046872[metal ion binding] GO:0051726[regulation of cell cycle] GO:0060644[mammary gland epithelial cell differentiation] GO:0065002[intracellular protein transmembrane transport] GO:0090314[positive regulation of protein targeting to membrane] GO:0106310[protein serine kinase activity] GO:0140677[molecular function activator activity] GO:2000147[positive regulation of cell motility]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
M0R0P9 [Direct mapping] Non-specific serine/threonine protein kinase
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MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC RAS pathway related proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Amplifications COSMIC Somatic Mutations Human disease related genes Cancers Cancers of the breast and female genital organs Congenital disorders of metabolism Other congenital disorders of metabolism Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674[protein serine/threonine kinase activity] GO:0043491[protein kinase B signaling]
The Human Protein Atlas project is funded
