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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:176.7 nTPM
HPA Brain:95.5 nTPM
GTEx:176.7 nTPM
FANTOM5:75.6 Scaled Tags Per Million
Pig:117.4 nTPM
Mouse:81.3 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 82.4
2019 Male, age 18, unknown 98.4
2411 Female, age 72, unknown 90.0
1827 Male, age 72, unknown 88.2
2828 Female, age 72, unknown 88.0
2586 Male, age 75, left hemisphere 86.9
1870 Female, age 42, unknown 85.6
2666 Male, age 74, left hemisphere 76.6
1833 Male, age 53, unknown 75.1
2219 Male, age 76, both hemispheres 70.0
1830 Male, age 51, unknown 64.7
Dorsal raphe nucleus
nTPM: 77.4
1828 Male, age 53, unknown 88.6
2750 Male, age 76, both hemispheres 85.5
2298 Female, age 72, unknown 76.1
2047 Male, age 72, unknown 69.3
2016 Female, age 72, unknown 67.7
Inferior colliculus
nTPM: 70.2
1890 Male, age 53, unknown 79.8
2097 Female, age 72, unknown 77.9
1848 Female, age 42, unknown 64.5
2849 Male, age 72, unknown 58.6
Median raphe nucleus
nTPM: 75.2
2220 Male, age 76, midline 75.2
Periaquaductal grey, anterior
nTPM: 76.8
1795 Male, age 51, unknown 81.1
1947 Male, age 18, unknown 74.8
2502 Female, age 75, unknown 74.3
Periaquaductal grey, dorsal
nTPM: 63.2
1831 Male, age 72, unknown 73.7
2464 Female, age 72, unknown 67.3
1840 Male, age 53, unknown 57.9
2850 Male, age 76, both hemispheres 53.8
Periaquaductal grey, lateral
nTPM: 61.0
2272 Male, age 74, both hemispheres 63.1
2053 Male, age 18, unknown 61.4
2140 Male, age 76, both hemispheres 58.7
Pretectal area
nTPM: 84.3
2007 Male, age 72, unknown 110.4
1816 Male, age 51, unknown 109.5
1817 Female, age 42, unknown 107.3
1944 Female, age 72, unknown 101.9
1815 Male, age 53, unknown 90.3
2667 Female, age 75, unknown 88.4
2316 Male, age 76, right hemisphere 68.0
2273 Male, age 74, both hemispheres 66.4
2224 Female, age 72, unknown 66.2
2825 Male, age 18, unknown 63.3
2407 Male, age 75, both hemispheres 55.4
Red nucleus
nTPM: 95.5
2503 Female, age 72, unknown 114.1
2588 Male, age 74, left hemisphere 101.9
1821 Female, age 72, unknown 100.1
2785 Male, age 18, unknown 98.4
1954 Female, age 42, unknown 98.2
1904 Male, age 53, unknown 94.2
2769 Male, age 72, unknown 93.8
1865 Male, age 51, unknown 93.7
2227 Male, age 72, unknown 91.4
2823 Male, age 76, right hemisphere 91.1
2725 Female, age 75, unknown 90.8
2584 Male, age 75, left hemisphere 77.9
Substantia nigra
nTPM: 82.7
1851 Male, age 51, unknown 99.8
1916 Female, age 42, unknown 99.2
1889 Female, age 72, unknown 96.2
2699 Male, age 18, unknown 81.4
2409 Female, age 72, unknown 80.9
2665 Male, age 74, both hemispheres 79.2
1941 Male, age 53, unknown 78.7
2590 Female, age 75, unknown 73.3
2583 Male, age 75, right hemisphere 70.2
2241 Male, age 72, unknown 68.1
Superior colliculus
nTPM: 78.7
2087 Female, age 72, unknown 96.4
1913 Female, age 42, unknown 90.2
2668 Female, age 75, unknown 87.3
1796 Male, age 53, unknown 84.0
2261 Male, age 18, unknown 83.1
1995 Male, age 72, unknown 76.4
1895 Male, age 76, right hemisphere 74.6
2587 Male, age 74, left hemisphere 71.8
2664 Male, age 75, both hemispheres 64.1
1839 Male, age 51, unknown 59.4
Ventral tegmental area
nTPM: 81.6
1915 Female, age 42, unknown 92.0
2410 Female, age 72, unknown 88.0
2223 Female, age 72, unknown 83.9
2218 Male, age 76, both hemispheres 82.6
1942 Male, age 51, unknown 79.2
2021 Male, age 53, unknown 64.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

176.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 176.7
Samples: 139

Max nTPM: 419.0
Min nTPM: 69.3
Std nTPM: 47.4
Median nTPM: 167.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 419.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 403.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 293.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 282.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 280.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 280.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 277.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 258.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 248.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 246.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 231.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 231.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 226.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 225.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 224.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 223.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 223.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 221.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 218.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 217.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 215.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 208.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 208.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 205.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 205.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 205.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 202.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 201.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 201.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 199.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 199.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 199.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 198.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 198.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 195.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 195.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 194.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 193.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 193.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 192.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 190.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 190.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 189.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 188.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 187.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 185.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 185.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 184.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 183.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 182.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 179.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 178.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 178.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 177.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 176.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 175.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 175.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 173.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 173.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 172.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 171.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 170.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 170.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 170.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 170.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 169.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 168.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 168.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 167.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 167.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 167.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 167.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 167.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 166.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 165.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 163.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 163.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 163.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 163.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 161.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 161.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 160.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 159.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 159.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 158.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 158.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 158.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 157.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 156.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 155.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 155.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 155.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 155.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 153.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 153.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 152.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 151.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 151.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 150.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 150.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 150.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 150.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 150.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 146.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 146.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 145.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 145.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 145.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 145.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 145.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 145.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 144.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 142.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 141.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 140.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 140.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 140.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 139.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 138.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 138.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 137.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 136.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 135.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 135.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 131.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 130.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 130.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 130.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 129.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 128.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 124.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 124.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 123.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 117.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 115.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 115.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 114.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 105.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 69.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

75.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 75.6
FF:10158-103A5 76 years, female 75.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

117.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 113.5
Samples: 4

Max nTPM: 143.5
Min nTPM: 90.2
Sample A Female 143.5
Sample B Female 90.2
Sample C Male 125.5
Sample D Male 94.6
Midbrain
nTPM: 117.4
Samples: 4

Max nTPM: 160.9
Min nTPM: 77.0
Sample A Female 160.9
Sample B Female 122.7
Sample C Male 109.1
Sample D Male 77.0
Periaqueductal gray
nTPM: 98.9
Samples: 3

Max nTPM: 110.0
Min nTPM: 82.3
Sample B Female 104.3
Sample C Male 110.0
Sample D Male 82.3
Superior colliculi
nTPM: 116.3
Samples: 4

Max nTPM: 132.6
Min nTPM: 101.7
Sample A Female 132.6
Sample B Female 106.6
Sample C Male 124.3
Sample D Male 101.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

81.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 81.4
Samples: 4

Max nTPM: 94.4
Min nTPM: 70.1
Sample A Male 94.4
Sample B Male 70.1
Sample C Female 73.9
Sample D Female 87.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
69262325 Antisense, RP_050303_02_A06, Mouse strain C57BL/6J (56 days, male) 2.4

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