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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
90.0
nTPM
HPA:
3.3
nTPM
GTEx:
90.0
nTPM
FANTOM5:
25.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA005157
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
3.3
Female, age 60
Liver sample 21 nTPM: 3.8
Male, age 54
Liver sample 23 nTPM: 3.5
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 1.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 3.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 1.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 5.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 3.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 3.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 3.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 3.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
90.0
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 90.0
Samples: 226
Max nTPM: 263.5
Min nTPM: 29.6
Std nTPM: 35.2
Median nTPM: 84.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
263.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
187.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
182.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
172.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
168.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
166.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
160.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
159.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
153.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
152.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
152.2
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
150.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
150.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
145.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
145.4
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
144.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
143.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
138.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
136.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
136.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
136.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
136.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
134.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
133.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
133.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
132.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
131.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
130.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
129.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
129.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
128.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
128.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
127.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
127.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
126.4
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
126.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
126.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
125.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
125.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
124.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
122.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
120.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
119.8
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
119.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
119.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
119.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
117.4
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
117.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
116.0
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
115.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
115.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
114.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
114.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
114.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
114.0
GTEX-17F96-1226-SM-79OK2
70-79 years, male
114.0
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
113.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
113.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
111.3
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
110.5
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
110.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
110.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
109.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
109.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
108.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
108.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
108.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
107.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
107.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
107.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
107.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
107.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
107.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
106.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
105.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
105.7
GTEX-X261-1726-SM-4PQYT
50-59 years, male
105.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
104.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
104.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
103.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
102.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
100.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
100.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
100.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
99.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
98.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
97.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
97.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
97.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
96.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
96.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
95.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
95.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
95.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
95.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
94.9
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
94.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
93.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
92.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
91.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
91.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
90.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
90.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
90.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
90.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
89.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
88.9
GTEX-1B933-1226-SM-731DW
50-59 years, female
88.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
87.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
87.4
GTEX-S33H-1626-SM-4AD68
30-39 years, male
86.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
85.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
84.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
84.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
83.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
83.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
82.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
81.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
81.6
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
80.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
80.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
79.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
79.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
78.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
78.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
77.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
77.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
77.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
77.6
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
76.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
76.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
76.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
76.0
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
75.9
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
75.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
75.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
75.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
74.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
74.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
74.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
73.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
73.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
73.8
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
73.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
73.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
72.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
72.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
71.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
71.4
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
71.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
71.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
70.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
70.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
70.9
GTEX-1399T-0826-SM-5IFES
60-69 years, male
70.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
70.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
70.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
69.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
69.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
69.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
68.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
68.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
68.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
67.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
67.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
67.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
66.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
66.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
64.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
64.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
64.1
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
63.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
63.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
62.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
62.1
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
61.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
61.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
61.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
60.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
60.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
59.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
59.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
58.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
58.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
58.2
GTEX-18A7A-1526-SM-72D69
50-59 years, female
57.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
57.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
57.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
57.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
56.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
55.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
55.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
55.0
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
54.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
54.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
52.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
51.9
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
51.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
51.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
51.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
48.8
GTEX-17HHE-0126-SM-79398
50-59 years, male
47.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
46.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
45.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
45.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
45.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
44.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
43.3
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
42.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
42.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
41.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
40.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
40.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
39.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
39.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
38.3
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
38.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
37.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
36.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
35.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
35.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
34.5
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
34.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
32.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
32.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
29.6
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
