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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:224.2 nTPM
HPA Brain:180.8 nTPM
GTEx:224.2 nTPM
FANTOM5:94.8 Scaled Tags Per Million
Pig:205.2 nTPM
Mouse:105.6 nTPM
Allen mouse:10.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

180.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 154.6
2586 Male, age 75, left hemisphere 178.9
2411 Female, age 72, unknown 175.2
2019 Male, age 18, unknown 172.3
1827 Male, age 72, unknown 171.5
2666 Male, age 74, left hemisphere 167.5
2828 Female, age 72, unknown 161.1
1870 Female, age 42, unknown 136.9
2219 Male, age 76, both hemispheres 129.9
1833 Male, age 53, unknown 127.2
1830 Male, age 51, unknown 125.7
Dorsal raphe nucleus
nTPM: 167.8
2298 Female, age 72, unknown 224.0
2047 Male, age 72, unknown 177.2
2750 Male, age 76, both hemispheres 164.4
1828 Male, age 53, unknown 153.7
2016 Female, age 72, unknown 119.7
Inferior colliculus
nTPM: 127.1
2097 Female, age 72, unknown 151.8
1890 Male, age 53, unknown 127.7
1848 Female, age 42, unknown 123.2
2849 Male, age 72, unknown 105.6
Median raphe nucleus
nTPM: 180.8
2220 Male, age 76, midline 180.8
Periaquaductal grey, anterior
nTPM: 166.5
1795 Male, age 51, unknown 189.8
2502 Female, age 75, unknown 156.5
1947 Male, age 18, unknown 153.2
Periaquaductal grey, dorsal
nTPM: 114.9
1831 Male, age 72, unknown 126.4
1840 Male, age 53, unknown 124.7
2464 Female, age 72, unknown 113.6
2850 Male, age 76, both hemispheres 95.1
Periaquaductal grey, lateral
nTPM: 121.8
2053 Male, age 18, unknown 136.4
2272 Male, age 74, both hemispheres 129.5
2140 Male, age 76, both hemispheres 99.3
Pretectal area
nTPM: 172.7
1816 Male, age 51, unknown 236.2
2007 Male, age 72, unknown 229.9
1944 Female, age 72, unknown 224.9
1817 Female, age 42, unknown 204.4
1815 Male, age 53, unknown 176.3
2224 Female, age 72, unknown 161.5
2667 Female, age 75, unknown 153.5
2273 Male, age 74, both hemispheres 149.7
2825 Male, age 18, unknown 129.5
2316 Male, age 76, right hemisphere 118.1
2407 Male, age 75, both hemispheres 115.5
Red nucleus
nTPM: 142.4
2785 Male, age 18, unknown 167.4
2503 Female, age 72, unknown 162.0
1821 Female, age 72, unknown 161.3
2584 Male, age 75, left hemisphere 143.3
2588 Male, age 74, left hemisphere 139.5
2769 Male, age 72, unknown 137.6
2227 Male, age 72, unknown 137.4
2725 Female, age 75, unknown 137.2
1954 Female, age 42, unknown 136.8
1904 Male, age 53, unknown 135.6
1865 Male, age 51, unknown 127.8
2823 Male, age 76, right hemisphere 122.6
Substantia nigra
nTPM: 164.8
1916 Female, age 42, unknown 230.4
1851 Male, age 51, unknown 192.4
1941 Male, age 53, unknown 191.2
1889 Female, age 72, unknown 186.9
2665 Male, age 74, both hemispheres 168.2
2583 Male, age 75, right hemisphere 157.2
2590 Female, age 75, unknown 144.7
2699 Male, age 18, unknown 127.5
2241 Male, age 72, unknown 127.0
2409 Female, age 72, unknown 122.6
Superior colliculus
nTPM: 156.1
2668 Female, age 75, unknown 204.5
2087 Female, age 72, unknown 186.6
2261 Male, age 18, unknown 181.3
1796 Male, age 53, unknown 168.7
1913 Female, age 42, unknown 155.8
2587 Male, age 74, left hemisphere 150.5
2664 Male, age 75, both hemispheres 139.4
1995 Male, age 72, unknown 135.2
1839 Male, age 51, unknown 119.5
1895 Male, age 76, right hemisphere 119.4
Ventral tegmental area
nTPM: 160.8
2410 Female, age 72, unknown 199.7
1915 Female, age 42, unknown 186.2
2218 Male, age 76, both hemispheres 156.9
1942 Male, age 51, unknown 143.4
2021 Male, age 53, unknown 141.6
2223 Female, age 72, unknown 137.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

224.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 224.2
Samples: 139

Max nTPM: 418.7
Min nTPM: 85.0
Std nTPM: 53.2
Median nTPM: 217.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 418.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 404.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 376.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 330.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 329.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 324.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 318.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 315.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 312.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 311.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 310.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 301.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 301.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 300.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 300.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 299.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 296.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 294.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 293.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 291.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 280.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 276.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 266.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 265.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 260.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 260.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 260.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 257.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 256.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 256.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 255.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 253.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 253.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 248.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 248.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 247.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 243.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 243.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 243.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 242.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 242.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 242.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 241.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 241.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 241.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 239.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 239.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 236.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 233.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 233.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 233.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 233.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 232.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 232.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 230.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 229.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 228.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 227.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 227.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 226.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 226.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 225.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 225.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 224.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 224.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 223.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 222.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 221.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 217.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 217.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 217.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 214.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 213.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 212.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 212.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 211.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 211.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 210.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 209.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 208.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 206.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 204.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 204.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 204.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 204.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 204.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 203.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 203.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 201.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 199.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 198.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 197.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 197.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 196.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 193.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 193.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 192.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 192.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 192.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 191.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 191.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 191.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 190.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 190.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 190.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 189.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 188.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 187.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 186.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 185.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 185.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 185.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 184.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 179.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 178.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 177.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 176.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 176.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 175.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 175.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 175.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 173.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 172.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 171.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 170.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 168.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 166.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 163.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 158.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 158.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 156.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 155.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 154.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 143.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 140.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 134.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 130.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 120.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 85.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

94.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 94.8
FF:10158-103A5 76 years, female 94.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

205.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 205.1
Samples: 4

Max nTPM: 275.4
Min nTPM: 143.7
Sample A Female 275.4
Sample B Female 189.9
Sample C Male 211.3
Sample D Male 143.7
Midbrain
nTPM: 202.0
Samples: 4

Max nTPM: 279.1
Min nTPM: 163.6
Sample A Female 279.1
Sample B Female 194.5
Sample C Male 170.8
Sample D Male 163.6
Periaqueductal gray
nTPM: 169.9
Samples: 3

Max nTPM: 199.1
Min nTPM: 154.9
Sample B Female 154.9
Sample C Male 199.1
Sample D Male 155.6
Superior colliculi
nTPM: 205.2
Samples: 4

Max nTPM: 257.4
Min nTPM: 159.7
Sample A Female 257.4
Sample B Female 218.3
Sample C Male 185.3
Sample D Male 159.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

105.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 105.6
Samples: 4

Max nTPM: 120.5
Min nTPM: 92.4
Sample A Male 120.5
Sample B Male 100.9
Sample C Female 92.4
Sample D Female 108.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.7
75750398 Antisense, RP_060518_04_G08, Mouse strain C57BL/6J (56 days, male) 10.7

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