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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:124.4 nTPM
HPA Brain:93.1 nTPM
GTEx:124.4 nTPM
FANTOM5:125.4 Scaled Tags Per Million
Pig:138.6 nTPM
Mouse:337.7 nTPM
Allen mouse:9.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 71.8
2219 Male, age 76, both hemispheres 101.5
1870 Female, age 42, unknown 86.5
2828 Female, age 72, unknown 80.9
1833 Male, age 53, unknown 74.4
1827 Male, age 72, unknown 71.3
1830 Male, age 51, unknown 70.1
2666 Male, age 74, left hemisphere 66.4
2586 Male, age 75, left hemisphere 59.2
2019 Male, age 18, unknown 57.5
2411 Female, age 72, unknown 50.5
Dorsal raphe nucleus
nTPM: 63.0
1828 Male, age 53, unknown 71.4
2016 Female, age 72, unknown 67.6
2298 Female, age 72, unknown 63.6
2750 Male, age 76, both hemispheres 56.3
2047 Male, age 72, unknown 56.2
Inferior colliculus
nTPM: 92.9
2097 Female, age 72, unknown 112.3
1848 Female, age 42, unknown 96.4
2849 Male, age 72, unknown 84.3
1890 Male, age 53, unknown 78.8
Median raphe nucleus
nTPM: 67.9
2220 Male, age 76, midline 67.9
Periaquaductal grey, anterior
nTPM: 74.6
1795 Male, age 51, unknown 77.8
1947 Male, age 18, unknown 76.1
2502 Female, age 75, unknown 70.0
Periaquaductal grey, dorsal
nTPM: 74.9
2850 Male, age 76, both hemispheres 78.9
1831 Male, age 72, unknown 78.7
1840 Male, age 53, unknown 78.7
2464 Female, age 72, unknown 63.4
Periaquaductal grey, lateral
nTPM: 73.9
2053 Male, age 18, unknown 86.1
2140 Male, age 76, both hemispheres 68.6
2272 Male, age 74, both hemispheres 66.9
Pretectal area
nTPM: 93.1
2667 Female, age 75, unknown 123.7
1817 Female, age 42, unknown 117.6
1944 Female, age 72, unknown 116.7
1816 Male, age 51, unknown 95.0
1815 Male, age 53, unknown 93.9
2224 Female, age 72, unknown 91.6
2273 Male, age 74, both hemispheres 82.3
2825 Male, age 18, unknown 80.6
2007 Male, age 72, unknown 79.9
2316 Male, age 76, right hemisphere 73.7
2407 Male, age 75, both hemispheres 69.6
Red nucleus
nTPM: 74.5
1954 Female, age 42, unknown 94.6
1865 Male, age 51, unknown 88.8
2503 Female, age 72, unknown 87.2
2227 Male, age 72, unknown 81.7
2769 Male, age 72, unknown 80.9
1904 Male, age 53, unknown 78.8
1821 Female, age 72, unknown 77.0
2823 Male, age 76, right hemisphere 68.7
2785 Male, age 18, unknown 67.5
2725 Female, age 75, unknown 63.8
2588 Male, age 74, left hemisphere 62.8
2584 Male, age 75, left hemisphere 42.8
Substantia nigra
nTPM: 81.0
2699 Male, age 18, unknown 116.7
1889 Female, age 72, unknown 101.2
2665 Male, age 74, both hemispheres 92.4
1941 Male, age 53, unknown 87.8
1916 Female, age 42, unknown 79.0
1851 Male, age 51, unknown 75.2
2409 Female, age 72, unknown 70.0
2241 Male, age 72, unknown 68.4
2583 Male, age 75, right hemisphere 66.9
2590 Female, age 75, unknown 52.2
Superior colliculus
nTPM: 89.1
2668 Female, age 75, unknown 119.2
2087 Female, age 72, unknown 109.8
1995 Male, age 72, unknown 107.0
1913 Female, age 42, unknown 98.9
1895 Male, age 76, right hemisphere 91.9
1796 Male, age 53, unknown 76.1
1839 Male, age 51, unknown 75.6
2261 Male, age 18, unknown 74.4
2587 Male, age 74, left hemisphere 74.1
2664 Male, age 75, both hemispheres 64.2
Ventral tegmental area
nTPM: 69.6
1915 Female, age 42, unknown 80.5
2218 Male, age 76, both hemispheres 77.5
2223 Female, age 72, unknown 68.1
2410 Female, age 72, unknown 67.6
1942 Male, age 51, unknown 64.3
2021 Male, age 53, unknown 59.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

124.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 124.4
Samples: 139

Max nTPM: 225.5
Min nTPM: 46.8
Std nTPM: 39.0
Median nTPM: 120.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 225.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 219.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 218.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 218.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 218.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 213.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 209.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 192.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 191.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 191.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 189.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 188.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 182.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 180.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 180.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 178.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 176.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 174.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 168.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 167.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 164.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 164.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 163.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 157.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 156.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 155.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 154.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 154.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 153.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 153.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 153.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 152.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 152.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 151.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 150.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 146.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 146.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 145.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 145.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 144.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 141.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 141.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 139.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 139.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 138.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 136.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 136.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 135.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 134.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 132.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 132.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 132.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 132.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 131.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 131.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 130.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 130.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 128.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 128.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 127.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 127.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 127.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 126.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 125.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 123.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 123.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 123.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 122.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 121.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 120.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 119.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 119.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 118.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 117.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 115.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 115.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 115.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 113.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 112.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 110.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 110.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 109.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 109.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 108.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 108.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 107.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 106.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 106.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 106.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 106.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 105.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 104.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 103.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 103.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 103.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 102.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 101.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 100.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 100.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 99.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 98.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 98.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 98.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 96.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 96.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 96.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 95.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 93.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 89.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 89.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 88.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 88.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 88.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 86.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 86.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 85.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 85.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 83.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 82.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 81.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 80.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 79.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 79.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 78.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 77.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 74.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 74.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 74.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 74.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 73.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 72.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 71.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 71.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 71.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 71.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 69.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 54.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 50.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 46.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

125.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 125.4
FF:10158-103A5 76 years, female 125.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

138.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 134.0
Samples: 4

Max nTPM: 173.9
Min nTPM: 86.3
Sample A Female 86.3
Sample B Female 155.9
Sample C Male 119.8
Sample D Male 173.9
Midbrain
nTPM: 110.4
Samples: 4

Max nTPM: 154.3
Min nTPM: 58.0
Sample A Female 58.0
Sample B Female 134.7
Sample C Male 94.5
Sample D Male 154.3
Periaqueductal gray
nTPM: 119.3
Samples: 3

Max nTPM: 132.7
Min nTPM: 110.2
Sample B Female 114.9
Sample C Male 110.2
Sample D Male 132.7
Superior colliculi
nTPM: 138.6
Samples: 4

Max nTPM: 205.3
Min nTPM: 90.8
Sample A Female 131.5
Sample B Female 205.3
Sample C Male 90.8
Sample D Male 126.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

337.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 337.7
Samples: 4

Max nTPM: 353.9
Min nTPM: 314.9
Sample A Male 353.9
Sample B Male 314.9
Sample C Female 343.0
Sample D Female 339.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.3
77455034 Antisense, RP_070129_02_A05, Mouse strain C57BL/6J (56 days, male) 9.8
2507 Antisense, RP_040324_01_D06, Mouse strain C57BL/6J (56 days, male) 8.7
2508 Antisense, RP_040324_01_D06, Mouse strain C57BL/6J (56 days, male) 7.0
77866882 Antisense, RP_070129_02_A05, Mouse strain C57BL/6J (56 days, male) 7.0

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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