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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:28.5 nTPM
HPA Brain:45.5 nTPM
GTEx:28.5 nTPM
FANTOM5:98.1 Scaled Tags Per Million
Pig:10.5 nTPM
Mouse:15.4 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 38.4
2411 Female, age 72, unknown 45.6
1870 Female, age 42, unknown 45.5
2019 Male, age 18, unknown 43.6
1830 Male, age 51, unknown 42.9
1833 Male, age 53, unknown 42.6
2828 Female, age 72, unknown 37.1
2586 Male, age 75, left hemisphere 36.4
2666 Male, age 74, left hemisphere 32.1
1827 Male, age 72, unknown 30.4
2219 Male, age 76, both hemispheres 27.8
Dorsal raphe nucleus
nTPM: 31.4
2750 Male, age 76, both hemispheres 50.9
1828 Male, age 53, unknown 28.9
2047 Male, age 72, unknown 27.2
2298 Female, age 72, unknown 25.3
2016 Female, age 72, unknown 24.8
Inferior colliculus
nTPM: 25.6
1890 Male, age 53, unknown 28.8
1848 Female, age 42, unknown 26.3
2097 Female, age 72, unknown 23.6
2849 Male, age 72, unknown 23.5
Median raphe nucleus
nTPM: 32.0
2220 Male, age 76, midline 32.0
Periaquaductal grey, anterior
nTPM: 27.8
2502 Female, age 75, unknown 29.7
1947 Male, age 18, unknown 27.9
1795 Male, age 51, unknown 25.8
Periaquaductal grey, dorsal
nTPM: 22.0
2464 Female, age 72, unknown 26.9
1831 Male, age 72, unknown 23.9
2850 Male, age 76, both hemispheres 22.3
1840 Male, age 53, unknown 14.9
Periaquaductal grey, lateral
nTPM: 28.9
2272 Male, age 74, both hemispheres 33.7
2053 Male, age 18, unknown 28.5
2140 Male, age 76, both hemispheres 24.4
Pretectal area
nTPM: 28.9
2316 Male, age 76, right hemisphere 35.7
2407 Male, age 75, both hemispheres 32.6
1815 Male, age 53, unknown 32.5
2007 Male, age 72, unknown 31.0
2273 Male, age 74, both hemispheres 30.9
2667 Female, age 75, unknown 30.5
1817 Female, age 42, unknown 28.4
2825 Male, age 18, unknown 28.3
2224 Female, age 72, unknown 25.9
1944 Female, age 72, unknown 21.6
1816 Male, age 51, unknown 20.7
Red nucleus
nTPM: 45.5
1865 Male, age 51, unknown 53.8
1904 Male, age 53, unknown 51.2
2769 Male, age 72, unknown 50.9
2227 Male, age 72, unknown 49.2
2823 Male, age 76, right hemisphere 47.7
2785 Male, age 18, unknown 47.1
1821 Female, age 72, unknown 46.6
2503 Female, age 72, unknown 43.8
1954 Female, age 42, unknown 42.8
2588 Male, age 74, left hemisphere 41.8
2725 Female, age 75, unknown 35.6
2584 Male, age 75, left hemisphere 35.0
Substantia nigra
nTPM: 28.0
2583 Male, age 75, right hemisphere 35.9
2590 Female, age 75, unknown 35.2
1851 Male, age 51, unknown 33.4
1889 Female, age 72, unknown 33.1
2699 Male, age 18, unknown 28.8
1941 Male, age 53, unknown 27.4
1916 Female, age 42, unknown 25.2
2665 Male, age 74, both hemispheres 20.8
2409 Female, age 72, unknown 20.7
2241 Male, age 72, unknown 19.5
Superior colliculus
nTPM: 33.8
1913 Female, age 42, unknown 51.5
1995 Male, age 72, unknown 46.4
2587 Male, age 74, left hemisphere 38.5
1895 Male, age 76, right hemisphere 32.7
1839 Male, age 51, unknown 31.9
1796 Male, age 53, unknown 30.9
2668 Female, age 75, unknown 28.4
2087 Female, age 72, unknown 27.3
2261 Male, age 18, unknown 26.1
2664 Male, age 75, both hemispheres 24.5
Ventral tegmental area
nTPM: 33.9
2223 Female, age 72, unknown 47.0
2410 Female, age 72, unknown 34.4
2021 Male, age 53, unknown 32.4
1942 Male, age 51, unknown 31.0
2218 Male, age 76, both hemispheres 30.1
1915 Female, age 42, unknown 28.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

28.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 28.5
Samples: 139

Max nTPM: 116.1
Min nTPM: 7.8
Std nTPM: 18.1
Median nTPM: 24.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 116.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 111.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 108.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 106.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 81.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 74.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 58.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 58.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 49.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 48.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 47.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 47.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 46.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 46.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 45.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 42.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 41.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 40.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 39.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 37.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 36.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 35.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 34.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 34.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 34.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 33.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 33.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 33.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 31.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 31.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 31.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 31.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 31.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 30.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 30.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 30.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 29.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 29.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 29.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 29.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 29.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 28.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 27.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 27.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 27.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 27.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 27.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 26.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 26.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 26.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 26.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 26.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 26.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 26.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 25.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 25.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 25.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 25.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 25.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 25.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 25.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 25.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 24.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 24.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 24.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 24.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 24.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 24.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 24.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 24.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 24.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 23.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 23.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 23.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 23.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 23.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 23.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 23.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 23.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 23.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 22.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 22.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 22.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 22.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 22.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 22.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 21.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 21.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 21.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 21.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 21.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 21.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 20.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 20.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 20.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 20.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 20.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 20.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 20.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 19.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 19.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 19.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 18.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 18.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 18.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 18.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 18.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 18.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 17.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 17.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 17.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 17.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 17.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 17.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 16.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 16.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 16.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 16.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 14.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 14.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 13.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 13.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 13.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 13.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 13.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 12.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 12.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 12.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 11.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 11.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 11.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 11.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 9.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 7.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

98.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 98.1
FF:10158-103A5 76 years, female 98.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

10.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 10.4
Samples: 4

Max nTPM: 13.5
Min nTPM: 8.2
Sample A Female 8.2
Sample B Female 10.4
Sample C Male 9.3
Sample D Male 13.5
Midbrain
nTPM: 9.2
Samples: 4

Max nTPM: 13.8
Min nTPM: 7.5
Sample A Female 13.8
Sample B Female 7.5
Sample C Male 7.9
Sample D Male 7.5
Periaqueductal gray
nTPM: 8.3
Samples: 3

Max nTPM: 9.0
Min nTPM: 7.3
Sample B Female 7.3
Sample C Male 9.0
Sample D Male 8.6
Superior colliculi
nTPM: 10.5
Samples: 4

Max nTPM: 13.6
Min nTPM: 8.1
Sample A Female 10.1
Sample B Female 13.6
Sample C Male 8.1
Sample D Male 10.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

15.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 15.4
Samples: 4

Max nTPM: 18.2
Min nTPM: 14.4
Sample A Male 14.4
Sample B Male 14.5
Sample C Female 18.2
Sample D Female 14.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
69816308 Antisense, RP_050505_04_G08, Mouse strain C57BL/6J (56 days, male) 0.5

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