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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:138.0 nTPM
HPA Brain:89.9 nTPM
GTEx:138.0 nTPM
FANTOM5:7.5 Scaled Tags Per Million
Pig:116.2 nTPM
Mouse:107.1 nTPM
Allen mouse:3.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

89.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 63.5
2586 Male, age 75, left hemisphere 76.3
1827 Male, age 72, unknown 75.8
2019 Male, age 18, unknown 75.7
2666 Male, age 74, left hemisphere 67.8
1870 Female, age 42, unknown 60.8
2411 Female, age 72, unknown 60.4
1833 Male, age 53, unknown 57.2
2828 Female, age 72, unknown 56.1
2219 Male, age 76, both hemispheres 52.9
1830 Male, age 51, unknown 52.4
Dorsal raphe nucleus
nTPM: 67.0
2298 Female, age 72, unknown 76.7
1828 Male, age 53, unknown 73.0
2047 Male, age 72, unknown 66.3
2016 Female, age 72, unknown 61.3
2750 Male, age 76, both hemispheres 57.6
Inferior colliculus
nTPM: 64.1
2097 Female, age 72, unknown 76.0
1890 Male, age 53, unknown 64.6
1848 Female, age 42, unknown 60.8
2849 Male, age 72, unknown 55.0
Median raphe nucleus
nTPM: 61.0
2220 Male, age 76, midline 61.0
Periaquaductal grey, anterior
nTPM: 72.1
1947 Male, age 18, unknown 76.5
1795 Male, age 51, unknown 72.2
2502 Female, age 75, unknown 67.7
Periaquaductal grey, dorsal
nTPM: 63.5
2850 Male, age 76, both hemispheres 74.3
1840 Male, age 53, unknown 63.8
1831 Male, age 72, unknown 60.8
2464 Female, age 72, unknown 55.0
Periaquaductal grey, lateral
nTPM: 65.4
2140 Male, age 76, both hemispheres 69.0
2053 Male, age 18, unknown 67.9
2272 Male, age 74, both hemispheres 59.2
Pretectal area
nTPM: 82.2
1816 Male, age 51, unknown 108.0
1944 Female, age 72, unknown 102.7
1817 Female, age 42, unknown 97.5
1815 Male, age 53, unknown 90.5
2007 Male, age 72, unknown 85.7
2273 Male, age 74, both hemispheres 79.3
2224 Female, age 72, unknown 79.1
2667 Female, age 75, unknown 78.9
2316 Male, age 76, right hemisphere 64.3
2407 Male, age 75, both hemispheres 59.5
2825 Male, age 18, unknown 59.1
Red nucleus
nTPM: 61.0
1821 Female, age 72, unknown 93.1
2725 Female, age 75, unknown 72.2
2785 Male, age 18, unknown 66.3
2823 Male, age 76, right hemisphere 61.8
1954 Female, age 42, unknown 60.6
1865 Male, age 51, unknown 59.2
2584 Male, age 75, left hemisphere 57.6
1904 Male, age 53, unknown 56.2
2227 Male, age 72, unknown 54.6
2503 Female, age 72, unknown 53.1
2769 Male, age 72, unknown 48.7
2588 Male, age 74, left hemisphere 48.3
Substantia nigra
nTPM: 89.9
2241 Male, age 72, unknown 125.0
1916 Female, age 42, unknown 112.2
2409 Female, age 72, unknown 102.3
1851 Male, age 51, unknown 99.3
1889 Female, age 72, unknown 91.9
1941 Male, age 53, unknown 91.2
2699 Male, age 18, unknown 71.5
2590 Female, age 75, unknown 69.6
2583 Male, age 75, right hemisphere 68.1
2665 Male, age 74, both hemispheres 68.0
Superior colliculus
nTPM: 68.1
2087 Female, age 72, unknown 81.8
2261 Male, age 18, unknown 77.4
2668 Female, age 75, unknown 77.3
2587 Male, age 74, left hemisphere 71.7
1796 Male, age 53, unknown 65.5
2664 Male, age 75, both hemispheres 63.8
1913 Female, age 42, unknown 63.6
1895 Male, age 76, right hemisphere 62.3
1995 Male, age 72, unknown 60.7
1839 Male, age 51, unknown 57.3
Ventral tegmental area
nTPM: 68.4
1915 Female, age 42, unknown 81.5
2410 Female, age 72, unknown 74.0
2218 Male, age 76, both hemispheres 72.5
1942 Male, age 51, unknown 64.3
2021 Male, age 53, unknown 63.0
2223 Female, age 72, unknown 55.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

138.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 138.0
Samples: 139

Max nTPM: 256.5
Min nTPM: 67.7
Std nTPM: 36.0
Median nTPM: 134.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 256.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 234.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 230.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 229.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 226.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 215.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 214.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 210.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 202.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 201.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 201.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 195.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 191.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 184.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 184.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 182.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 178.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 177.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 177.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 171.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 169.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 169.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 168.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 167.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 165.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 165.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 162.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 161.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 161.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 160.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 160.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 159.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 157.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 156.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 156.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 153.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 153.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 153.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 153.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 152.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 152.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 152.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 150.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 150.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 149.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 149.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 147.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 147.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 147.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 146.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 146.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 145.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 144.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 143.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 142.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 142.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 141.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 141.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 140.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 140.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 140.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 139.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 139.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 138.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 137.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 136.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 135.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 135.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 134.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 134.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 133.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 132.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 128.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 128.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 127.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 126.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 126.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 126.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 126.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 126.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 125.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 125.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 125.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 125.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 123.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 123.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 123.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 123.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 123.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 122.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 122.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 122.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 121.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 121.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 120.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 120.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 120.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 119.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 119.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 119.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 119.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 118.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 118.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 118.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 117.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 115.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 113.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 113.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 113.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 112.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 111.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 110.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 110.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 109.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 108.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 106.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 105.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 105.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 102.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 101.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 99.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 98.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 98.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 98.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 97.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 96.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 96.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 93.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 92.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 89.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 89.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 84.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 81.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 77.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 74.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 71.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 71.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 70.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 67.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

7.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 7.5
FF:10158-103A5 76 years, female 7.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 96.0
Samples: 4

Max nTPM: 123.1
Min nTPM: 75.4
Sample A Female 123.1
Sample B Female 89.1
Sample C Male 96.5
Sample D Male 75.4
Midbrain
nTPM: 105.6
Samples: 4

Max nTPM: 125.2
Min nTPM: 87.4
Sample A Female 103.6
Sample B Female 87.4
Sample C Male 125.2
Sample D Male 106.3
Periaqueductal gray
nTPM: 79.0
Samples: 3

Max nTPM: 87.3
Min nTPM: 68.0
Sample B Female 68.0
Sample C Male 87.3
Sample D Male 81.8
Superior colliculi
nTPM: 116.2
Samples: 4

Max nTPM: 128.8
Min nTPM: 104.6
Sample A Female 128.8
Sample B Female 104.6
Sample C Male 123.7
Sample D Male 107.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 107.2
Samples: 4

Max nTPM: 109.6
Min nTPM: 104.6
Sample A Male 105.6
Sample B Male 109.6
Sample C Female 104.6
Sample D Female 108.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.5
564750 Antisense, RP_040826_01_C05, Mouse strain C57BL/6J (56 days, male) 3.5

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