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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:27.9 nTPM
HPA Brain:19.3 nTPM
GTEx:27.9 nTPM
FANTOM5:19.7 Scaled Tags Per Million
Pig:44.7 nTPM
Mouse:184.9 nTPM
Allen mouse:9.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

19.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 14.2
2019 Male, age 18, unknown 16.7
2828 Female, age 72, unknown 15.8
1870 Female, age 42, unknown 14.7
1833 Male, age 53, unknown 14.4
2586 Male, age 75, left hemisphere 14.3
2219 Male, age 76, both hemispheres 14.2
2411 Female, age 72, unknown 13.7
1827 Male, age 72, unknown 12.9
1830 Male, age 51, unknown 12.6
2666 Male, age 74, left hemisphere 12.5
Dorsal raphe nucleus
nTPM: 17.9
2298 Female, age 72, unknown 22.2
2047 Male, age 72, unknown 19.7
2016 Female, age 72, unknown 17.2
1828 Male, age 53, unknown 16.6
2750 Male, age 76, both hemispheres 13.8
Inferior colliculus
nTPM: 19.3
1848 Female, age 42, unknown 20.5
2097 Female, age 72, unknown 20.4
1890 Male, age 53, unknown 19.6
2849 Male, age 72, unknown 16.8
Median raphe nucleus
nTPM: 14.1
2220 Male, age 76, midline 14.1
Periaquaductal grey, anterior
nTPM: 16.1
1947 Male, age 18, unknown 17.6
2502 Female, age 75, unknown 16.5
1795 Male, age 51, unknown 14.1
Periaquaductal grey, dorsal
nTPM: 15.3
1840 Male, age 53, unknown 18.5
2464 Female, age 72, unknown 15.3
2850 Male, age 76, both hemispheres 14.3
1831 Male, age 72, unknown 13.3
Periaquaductal grey, lateral
nTPM: 14.5
2272 Male, age 74, both hemispheres 19.8
2140 Male, age 76, both hemispheres 12.0
2053 Male, age 18, unknown 11.8
Pretectal area
nTPM: 15.7
2667 Female, age 75, unknown 18.6
1817 Female, age 42, unknown 18.4
1944 Female, age 72, unknown 18.2
2224 Female, age 72, unknown 17.9
2273 Male, age 74, both hemispheres 17.5
1816 Male, age 51, unknown 16.8
2007 Male, age 72, unknown 14.7
1815 Male, age 53, unknown 14.6
2825 Male, age 18, unknown 13.9
2316 Male, age 76, right hemisphere 12.4
2407 Male, age 75, both hemispheres 9.4
Red nucleus
nTPM: 15.6
1821 Female, age 72, unknown 21.3
2503 Female, age 72, unknown 18.5
1954 Female, age 42, unknown 17.4
2725 Female, age 75, unknown 16.6
1865 Male, age 51, unknown 15.9
2785 Male, age 18, unknown 15.9
2823 Male, age 76, right hemisphere 15.3
2769 Male, age 72, unknown 15.2
2227 Male, age 72, unknown 14.3
1904 Male, age 53, unknown 14.1
2588 Male, age 74, left hemisphere 12.4
2584 Male, age 75, left hemisphere 10.1
Substantia nigra
nTPM: 18.4
2241 Male, age 72, unknown 26.1
1916 Female, age 42, unknown 24.2
1851 Male, age 51, unknown 22.1
1889 Female, age 72, unknown 20.4
2699 Male, age 18, unknown 20.3
1941 Male, age 53, unknown 16.9
2409 Female, age 72, unknown 15.1
2665 Male, age 74, both hemispheres 13.4
2590 Female, age 75, unknown 13.2
2583 Male, age 75, right hemisphere 12.1
Superior colliculus
nTPM: 14.3
2087 Female, age 72, unknown 16.5
2587 Male, age 74, left hemisphere 16.2
1796 Male, age 53, unknown 16.1
1895 Male, age 76, right hemisphere 14.7
2668 Female, age 75, unknown 14.2
1995 Male, age 72, unknown 14.1
1839 Male, age 51, unknown 13.8
1913 Female, age 42, unknown 13.1
2261 Male, age 18, unknown 12.2
2664 Male, age 75, both hemispheres 11.7
Ventral tegmental area
nTPM: 16.4
1915 Female, age 42, unknown 19.5
2410 Female, age 72, unknown 18.6
2218 Male, age 76, both hemispheres 16.1
1942 Male, age 51, unknown 15.0
2021 Male, age 53, unknown 14.9
2223 Female, age 72, unknown 14.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 27.9
Samples: 139

Max nTPM: 65.5
Min nTPM: 12.3
Std nTPM: 9.4
Median nTPM: 26.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 65.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 63.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 62.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 56.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 50.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 49.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 49.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 47.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 41.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 41.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 41.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 39.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 38.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 38.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 37.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 36.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 36.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 36.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 35.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 34.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 34.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 34.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 34.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 33.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 33.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 33.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 32.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 32.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 32.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 32.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 32.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 31.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 31.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 31.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 31.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 31.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 31.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 31.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 31.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 30.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 30.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 30.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 30.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 30.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 29.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 29.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 29.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 29.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 28.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 28.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 28.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 28.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 28.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 27.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 27.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 27.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 27.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 27.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 27.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 27.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 27.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 27.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 26.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 26.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 26.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 26.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 26.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 26.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 26.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 26.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 25.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 25.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 25.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 25.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 25.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 25.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 25.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 24.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 24.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 24.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 24.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 24.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 24.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 24.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 24.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 24.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 23.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 23.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 23.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 23.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 23.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 23.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 23.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 23.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 23.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 23.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 23.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 22.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 22.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 22.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 21.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 21.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 21.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 21.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 21.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 20.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 20.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 20.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 20.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 19.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 19.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 19.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 19.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 18.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 18.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 18.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 18.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 18.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 18.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 18.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 18.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 18.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 17.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 17.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 16.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 16.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 16.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 15.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 14.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 14.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 13.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 12.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

19.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 19.7
FF:10158-103A5 76 years, female 19.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 44.7
Samples: 4

Max nTPM: 55.0
Min nTPM: 40.2
Sample A Female 55.0
Sample B Female 43.5
Sample C Male 40.2
Sample D Male 40.2
Midbrain
nTPM: 43.3
Samples: 4

Max nTPM: 66.3
Min nTPM: 27.1
Sample A Female 66.3
Sample B Female 43.8
Sample C Male 36.1
Sample D Male 27.1
Periaqueductal gray
nTPM: 37.7
Samples: 3

Max nTPM: 42.5
Min nTPM: 34.7
Sample B Female 35.8
Sample C Male 42.5
Sample D Male 34.7
Superior colliculi
nTPM: 42.2
Samples: 4

Max nTPM: 48.5
Min nTPM: 37.1
Sample A Female 48.5
Sample B Female 43.7
Sample C Male 37.1
Sample D Male 39.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

184.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 185.0
Samples: 4

Max nTPM: 193.9
Min nTPM: 173.4
Sample A Male 191.0
Sample B Male 193.9
Sample C Female 173.4
Sample D Female 181.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.2
74800914 Antisense, RP_060315_02_A06, Mouse strain C57BL/6J (56 days, male) 13.4
532592 Antisense, RP_040810_02_D03, Mouse strain C57BL/6J (56 days, male) 4.9

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