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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
152.8
nTPM
HPA:
152.8
nTPM
GTEx:
98.8
nTPM
FANTOM5:
931.8
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA020043
Antibody CAB005868
Cholangiocytes
Not detected
Low
Hepatocytes
Low
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
152.8
Female, age 60
Liver sample 21 nTPM: 93.8
Male, age 54
Liver sample 23 nTPM: 120.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 82.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 297.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 133.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 190.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 270.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 94.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 105.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 137.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
98.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 98.8
Samples: 226
Max nTPM: 289.7
Min nTPM: 40.7
Std nTPM: 34.4
Median nTPM: 92.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
289.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
241.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
192.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
192.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
184.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
183.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
183.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
174.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
170.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
165.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
161.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
158.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
155.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
154.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
153.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
151.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
150.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
148.7
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
148.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
146.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
143.9
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
143.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
140.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
140.0
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
139.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
138.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
134.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
134.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
133.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
133.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
133.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
133.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
133.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
132.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
131.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
131.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
130.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
130.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
129.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
128.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
126.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
125.0
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
124.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
124.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
122.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
122.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
122.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
122.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
121.9
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
121.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
118.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
118.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
117.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
117.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
116.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
116.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
115.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
114.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
113.7
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
112.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
112.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
111.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
110.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
110.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
109.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
109.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
109.7
GTEX-14XAO-0226-SM-68728
60-69 years, female
109.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
108.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
108.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
107.1
GTEX-QEL4-1226-SM-447A4
50-59 years, male
106.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
105.6
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
105.2
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
104.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
104.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
104.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
104.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
104.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
103.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
103.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
103.1
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
103.1
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
103.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
102.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
102.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
101.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
101.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
101.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
101.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
100.5
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
99.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
99.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
99.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
99.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
99.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
99.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
99.2
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
99.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
98.9
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
98.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
98.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
97.9
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
97.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
96.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
95.8
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
95.3
GTEX-S32W-1926-SM-4AD63
50-59 years, female
94.4
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
93.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
93.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
93.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
93.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
93.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
92.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
92.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
91.9
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
91.3
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
91.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
91.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
90.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
90.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
90.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
89.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
89.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
89.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
88.9
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
88.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
88.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
88.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
88.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
88.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
87.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
87.8
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
87.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
86.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
86.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
86.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
85.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
85.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
84.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
84.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
84.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
84.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
84.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
83.8
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
83.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
82.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
82.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
81.6
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
81.5
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
81.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
80.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
80.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
80.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
80.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
79.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
79.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
79.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
79.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
78.5
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
78.2
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
78.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
78.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
78.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
77.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
76.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
76.7
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
76.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
76.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
75.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
74.6
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
74.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
74.5
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
74.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
74.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
73.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
73.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
73.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
73.2
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
72.7
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
72.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
71.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
70.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
70.1
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
69.9
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
69.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
69.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
69.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
68.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
68.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
68.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
67.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
67.7
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
67.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
65.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
65.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
65.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
65.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
65.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
64.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
63.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
63.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
62.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
62.3
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
62.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
61.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
59.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
58.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
58.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
57.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
56.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
55.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
54.3
GTEX-14JG1-1626-SM-664NH
40-49 years, male
53.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
53.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
52.8
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
52.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
51.0
GTEX-R53T-0326-SM-48FEC
50-59 years, female
50.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
49.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
49.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
48.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
47.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
45.2
GTEX-REY6-1226-SM-48FDR
60-69 years, male
44.9
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
40.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
