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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:89.9 nTPM
HPA Brain:237.6 nTPM
GTEx:89.9 nTPM
FANTOM5:120.0 Scaled Tags Per Million
Pig:70.4 nTPM
Mouse:49.7 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

237.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 90.5
2219 Male, age 76, both hemispheres 120.6
2666 Male, age 74, left hemisphere 117.5
2411 Female, age 72, unknown 110.6
2828 Female, age 72, unknown 94.3
1870 Female, age 42, unknown 84.0
2586 Male, age 75, left hemisphere 80.7
1833 Male, age 53, unknown 80.1
1830 Male, age 51, unknown 79.3
1827 Male, age 72, unknown 78.0
2019 Male, age 18, unknown 59.5
Dorsal raphe nucleus
nTPM: 170.8
2047 Male, age 72, unknown 267.7
2298 Female, age 72, unknown 209.0
2750 Male, age 76, both hemispheres 198.6
1828 Male, age 53, unknown 91.0
2016 Female, age 72, unknown 87.8
Inferior colliculus
nTPM: 49.8
1890 Male, age 53, unknown 60.0
2097 Female, age 72, unknown 55.3
2849 Male, age 72, unknown 42.7
1848 Female, age 42, unknown 41.2
Median raphe nucleus
nTPM: 237.6
2220 Male, age 76, midline 237.6
Periaquaductal grey, anterior
nTPM: 99.2
1795 Male, age 51, unknown 119.3
1947 Male, age 18, unknown 97.1
2502 Female, age 75, unknown 81.3
Periaquaductal grey, dorsal
nTPM: 84.9
2850 Male, age 76, both hemispheres 99.1
1840 Male, age 53, unknown 87.8
1831 Male, age 72, unknown 80.6
2464 Female, age 72, unknown 71.9
Periaquaductal grey, lateral
nTPM: 69.8
2053 Male, age 18, unknown 71.7
2140 Male, age 76, both hemispheres 70.2
2272 Male, age 74, both hemispheres 67.7
Pretectal area
nTPM: 73.3
2224 Female, age 72, unknown 112.8
2825 Male, age 18, unknown 95.8
1815 Male, age 53, unknown 74.0
2667 Female, age 75, unknown 73.1
2273 Male, age 74, both hemispheres 71.3
1816 Male, age 51, unknown 68.1
1944 Female, age 72, unknown 67.8
1817 Female, age 42, unknown 64.3
2007 Male, age 72, unknown 60.9
2407 Male, age 75, both hemispheres 60.3
2316 Male, age 76, right hemisphere 57.5
Red nucleus
nTPM: 68.8
2584 Male, age 75, left hemisphere 93.4
2725 Female, age 75, unknown 90.8
1821 Female, age 72, unknown 79.8
1904 Male, age 53, unknown 72.3
1865 Male, age 51, unknown 67.0
2503 Female, age 72, unknown 64.0
2588 Male, age 74, left hemisphere 63.8
2823 Male, age 76, right hemisphere 63.8
2769 Male, age 72, unknown 62.5
2227 Male, age 72, unknown 59.6
1954 Female, age 42, unknown 58.1
2785 Male, age 18, unknown 50.8
Substantia nigra
nTPM: 185.0
1916 Female, age 42, unknown 377.8
1851 Male, age 51, unknown 275.6
2241 Male, age 72, unknown 222.4
2699 Male, age 18, unknown 214.1
1941 Male, age 53, unknown 161.7
2409 Female, age 72, unknown 161.2
2665 Male, age 74, both hemispheres 136.7
2590 Female, age 75, unknown 105.7
1889 Female, age 72, unknown 99.1
2583 Male, age 75, right hemisphere 96.1
Superior colliculus
nTPM: 70.7
2668 Female, age 75, unknown 97.6
1796 Male, age 53, unknown 84.8
2261 Male, age 18, unknown 79.2
2664 Male, age 75, both hemispheres 78.0
2587 Male, age 74, left hemisphere 69.6
1913 Female, age 42, unknown 69.5
2087 Female, age 72, unknown 69.1
1995 Male, age 72, unknown 59.6
1839 Male, age 51, unknown 54.9
1895 Male, age 76, right hemisphere 45.0
Ventral tegmental area
nTPM: 177.0
1915 Female, age 42, unknown 221.6
2410 Female, age 72, unknown 201.9
2021 Male, age 53, unknown 198.7
2218 Male, age 76, both hemispheres 164.5
2223 Female, age 72, unknown 144.8
1942 Male, age 51, unknown 130.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

89.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 89.9
Samples: 139

Max nTPM: 285.6
Min nTPM: 40.5
Std nTPM: 43.6
Median nTPM: 75.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 285.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 260.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 213.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 194.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 189.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 187.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 181.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 175.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 173.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 170.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 164.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 160.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 159.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 158.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 152.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 151.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 149.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 140.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 138.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 131.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 126.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 126.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 126.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 125.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 122.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 118.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 115.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 114.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 114.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 113.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 112.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 111.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 110.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 109.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 106.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 105.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 102.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 102.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 101.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 101.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 100.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 100.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 100.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 99.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 97.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 97.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 92.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 91.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 91.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 89.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 88.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 87.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 87.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 86.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 86.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 84.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 84.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 83.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 83.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 83.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 82.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 82.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 80.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 79.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 76.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 76.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 76.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 75.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 74.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 74.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 72.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 72.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 72.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 71.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 69.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 68.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 68.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 68.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 67.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 67.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 66.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 66.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 66.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 65.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 65.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 65.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 64.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 64.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 63.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 63.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 62.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 62.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 61.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 61.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 60.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 60.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 60.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 60.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 60.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 59.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 59.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 58.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 58.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 58.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 58.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 57.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 57.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 57.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 56.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 56.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 55.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 55.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 54.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 54.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 54.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 54.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 54.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 53.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 53.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 52.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 50.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 49.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 48.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 47.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 46.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 46.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 45.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 43.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 43.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 41.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 41.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

120.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 120.0
FF:10158-103A5 76 years, female 120.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

70.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 70.4
Samples: 4

Max nTPM: 90.7
Min nTPM: 40.5
Sample A Female 89.0
Sample B Female 61.5
Sample C Male 90.7
Sample D Male 40.5
Midbrain
nTPM: 46.0
Samples: 4

Max nTPM: 75.3
Min nTPM: 30.7
Sample A Female 75.3
Sample B Female 45.4
Sample C Male 32.5
Sample D Male 30.7
Periaqueductal gray
nTPM: 38.9
Samples: 3

Max nTPM: 53.7
Min nTPM: 30.9
Sample B Female 32.0
Sample C Male 53.7
Sample D Male 30.9
Superior colliculi
nTPM: 38.3
Samples: 4

Max nTPM: 50.6
Min nTPM: 27.1
Sample A Female 50.6
Sample B Female 44.6
Sample C Male 27.1
Sample D Male 30.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 49.7
Samples: 4

Max nTPM: 53.8
Min nTPM: 42.4
Sample A Male 53.8
Sample B Male 51.0
Sample C Female 42.4
Sample D Female 51.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
72004459 Antisense, RP_050915_03_A02, Mouse strain C57BL/6J (56 days, male) 0.8
74357572 Antisense, RP_050915_03_A02, Mouse strain C57BL/6J (56 days, male) 0.7

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