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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
70.1
nTPM
HPA:
30.0
nTPM
GTEx:
70.1
nTPM
FANTOM5:
96.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA011947
Cholangiocytes
Medium
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
30.0
Female, age 60
Liver sample 21 nTPM: 34.7
Male, age 54
Liver sample 23 nTPM: 22.3
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 29.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 17.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 32.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 29.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 22.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 50.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 29
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 32.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
70.1
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 70.1
Samples: 226
Max nTPM: 136.5
Min nTPM: 16.2
Std nTPM: 23.2
Median nTPM: 70.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
136.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
134.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
129.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
129.0
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
122.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
115.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
113.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
112.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
111.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
111.0
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
110.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
110.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
108.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
108.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
107.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
106.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
105.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
104.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
103.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
103.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
103.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
100.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
98.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
98.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
97.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
97.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
96.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
94.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
94.1
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
94.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
93.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
93.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
92.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
92.7
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
91.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
91.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
91.3
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
91.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
91.0
GTEX-RN64-1826-SM-48FDV
50-59 years, male
90.7
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
90.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
90.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
90.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
89.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
89.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
88.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
88.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
88.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
88.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
88.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
86.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
86.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
86.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
86.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
85.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
85.3
GTEX-14E7W-1526-SM-6871X
70-79 years, male
85.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
85.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
84.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
84.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
84.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
84.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
84.3
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
84.3
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
83.9
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
83.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
83.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
83.3
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
82.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
82.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
82.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
81.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
81.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
81.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
81.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
80.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
80.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
80.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
80.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
80.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
79.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
79.9
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
79.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
79.3
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
79.3
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
78.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
78.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
77.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
77.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
77.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
77.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
76.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
76.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
76.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
75.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
75.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
75.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
75.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
74.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
74.1
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
74.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
73.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
73.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
73.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
73.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
73.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
72.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
72.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
71.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
71.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
70.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
70.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
70.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
70.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
70.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
70.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
69.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
69.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
69.3
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
69.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
68.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
68.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
68.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
68.2
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
67.6
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
67.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
67.4
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
67.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
67.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
66.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
66.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
66.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
65.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
65.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
65.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
65.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
64.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
63.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
63.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
62.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
62.4
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
62.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
62.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
61.9
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
61.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
61.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
61.0
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
61.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
60.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
59.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
58.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
58.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
58.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
57.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
56.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
55.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
55.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
55.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
55.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
55.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
55.1
GTEX-QEL4-1226-SM-447A4
50-59 years, male
54.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
54.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
54.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
54.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
53.8
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
53.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
53.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
52.8
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
52.6
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
51.2
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
50.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
50.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
48.9
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
48.6
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
48.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
48.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
48.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
47.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
46.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
46.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
46.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
46.0
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
45.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
45.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
45.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
45.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
45.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
44.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
44.7
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
44.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
44.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
42.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
42.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
41.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
40.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
40.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
40.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
40.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
39.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
39.7
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
39.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
38.9
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
38.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
38.0
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
37.9
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
37.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
37.6
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
37.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
37.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
36.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
36.4
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
35.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
35.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
35.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
35.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
35.0
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
33.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
31.9
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
30.7
GTEX-R53T-0326-SM-48FEC
50-59 years, female
30.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
30.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
29.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
29.5
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
23.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
16.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
