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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:16.5 nTPM
HPA Brain:71.4 nTPM
GTEx:16.5 nTPM
FANTOM5:64.4 Scaled Tags Per Million
Pig:20.7 nTPM
Mouse:9.0 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

71.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 61.9
2586 Male, age 75, left hemisphere 73.2
2666 Male, age 74, left hemisphere 72.0
2019 Male, age 18, unknown 71.3
1830 Male, age 51, unknown 64.4
1833 Male, age 53, unknown 63.6
2411 Female, age 72, unknown 62.6
1870 Female, age 42, unknown 59.6
2828 Female, age 72, unknown 59.1
1827 Male, age 72, unknown 48.8
2219 Male, age 76, both hemispheres 44.0
Dorsal raphe nucleus
nTPM: 37.8
2750 Male, age 76, both hemispheres 58.5
1828 Male, age 53, unknown 38.7
2016 Female, age 72, unknown 35.9
2047 Male, age 72, unknown 28.1
2298 Female, age 72, unknown 27.8
Inferior colliculus
nTPM: 41.6
1848 Female, age 42, unknown 45.0
2849 Male, age 72, unknown 45.0
1890 Male, age 53, unknown 42.8
2097 Female, age 72, unknown 33.6
Median raphe nucleus
nTPM: 33.0
2220 Male, age 76, midline 33.0
Periaquaductal grey, anterior
nTPM: 48.1
1947 Male, age 18, unknown 65.4
1795 Male, age 51, unknown 41.9
2502 Female, age 75, unknown 37.1
Periaquaductal grey, dorsal
nTPM: 29.5
2464 Female, age 72, unknown 42.1
1831 Male, age 72, unknown 28.3
1840 Male, age 53, unknown 25.1
2850 Male, age 76, both hemispheres 22.3
Periaquaductal grey, lateral
nTPM: 29.7
2272 Male, age 74, both hemispheres 33.0
2053 Male, age 18, unknown 31.7
2140 Male, age 76, both hemispheres 24.4
Pretectal area
nTPM: 45.3
2407 Male, age 75, both hemispheres 69.4
2007 Male, age 72, unknown 62.5
1815 Male, age 53, unknown 57.3
1817 Female, age 42, unknown 55.4
2316 Male, age 76, right hemisphere 52.5
2825 Male, age 18, unknown 41.9
1944 Female, age 72, unknown 36.2
1816 Male, age 51, unknown 35.9
2667 Female, age 75, unknown 31.9
2224 Female, age 72, unknown 29.9
2273 Male, age 74, both hemispheres 25.6
Red nucleus
nTPM: 71.4
1904 Male, age 53, unknown 83.7
2584 Male, age 75, left hemisphere 82.6
1865 Male, age 51, unknown 81.4
2785 Male, age 18, unknown 77.7
2769 Male, age 72, unknown 75.0
2588 Male, age 74, left hemisphere 74.6
2227 Male, age 72, unknown 70.8
1821 Female, age 72, unknown 68.1
1954 Female, age 42, unknown 64.0
2823 Male, age 76, right hemisphere 60.7
2725 Female, age 75, unknown 59.5
2503 Female, age 72, unknown 59.4
Substantia nigra
nTPM: 43.0
2583 Male, age 75, right hemisphere 73.5
2590 Female, age 75, unknown 56.1
1851 Male, age 51, unknown 46.5
1889 Female, age 72, unknown 44.9
2409 Female, age 72, unknown 39.2
1916 Female, age 42, unknown 36.3
2665 Male, age 74, both hemispheres 35.3
2241 Male, age 72, unknown 34.2
1941 Male, age 53, unknown 33.8
2699 Male, age 18, unknown 30.2
Superior colliculus
nTPM: 53.0
2668 Female, age 75, unknown 77.4
1995 Male, age 72, unknown 61.5
1913 Female, age 42, unknown 58.9
2664 Male, age 75, both hemispheres 57.3
1895 Male, age 76, right hemisphere 55.0
1839 Male, age 51, unknown 53.1
2587 Male, age 74, left hemisphere 48.9
1796 Male, age 53, unknown 46.5
2261 Male, age 18, unknown 38.0
2087 Female, age 72, unknown 33.6
Ventral tegmental area
nTPM: 44.6
2223 Female, age 72, unknown 63.4
2410 Female, age 72, unknown 54.6
1942 Male, age 51, unknown 41.8
2021 Male, age 53, unknown 37.6
2218 Male, age 76, both hemispheres 36.7
1915 Female, age 42, unknown 33.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 16.5
Samples: 139

Max nTPM: 62.5
Min nTPM: 4.3
Std nTPM: 8.2
Median nTPM: 14.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 62.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 53.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 40.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 38.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 37.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 36.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 32.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 27.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 27.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 26.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 26.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 25.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 25.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 25.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 24.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 24.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 23.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 23.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 23.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 22.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 22.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 22.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 22.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 21.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 21.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 21.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 21.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 21.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 21.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 20.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 20.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 20.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 19.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 19.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 19.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 19.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 19.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 19.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 19.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 19.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 18.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 18.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 18.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 18.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 18.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 18.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 17.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 17.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 17.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 17.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 17.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 16.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 16.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 16.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 16.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 16.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 16.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 16.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 15.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 15.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 15.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 15.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 15.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 15.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 14.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 14.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 14.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 14.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 14.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 14.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 14.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 14.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 14.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 14.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 14.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 14.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 13.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 13.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 13.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 13.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 13.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 13.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 13.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 13.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 12.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 12.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 12.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 12.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 12.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 12.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 12.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 12.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 12.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 12.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 11.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 11.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 11.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 11.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 11.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 11.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 11.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 11.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 11.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 11.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 11.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 10.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 10.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 10.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 10.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 10.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 10.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 10.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 10.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 10.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 9.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 9.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 9.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 9.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 9.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 8.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 8.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 8.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 8.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 7.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 7.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 7.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 7.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 7.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 6.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 6.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 5.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 5.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 4.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

64.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 64.4
FF:10158-103A5 76 years, female 64.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 17.2
Samples: 4

Max nTPM: 20.0
Min nTPM: 14.8
Sample A Female 20.0
Sample B Female 16.4
Sample C Male 17.5
Sample D Male 14.8
Midbrain
nTPM: 20.7
Samples: 4

Max nTPM: 26.8
Min nTPM: 15.7
Sample A Female 26.8
Sample B Female 17.0
Sample C Male 23.3
Sample D Male 15.7
Periaqueductal gray
nTPM: 17.7
Samples: 3

Max nTPM: 20.1
Min nTPM: 14.4
Sample B Female 18.7
Sample C Male 20.1
Sample D Male 14.4
Superior colliculi
nTPM: 17.4
Samples: 4

Max nTPM: 19.8
Min nTPM: 13.0
Sample A Female 18.9
Sample B Female 13.0
Sample C Male 19.8
Sample D Male 18.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 9.0
Samples: 4

Max nTPM: 9.8
Min nTPM: 8.3
Sample A Male 8.5
Sample B Male 8.3
Sample C Female 9.3
Sample D Female 9.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
74363351 Antisense, RP_051019_03_C08, Mouse strain C57BL/6J (56 days, male) 3.1
73424053 Antisense, RP_051019_03_C08, Mouse strain C57BL/6J (56 days, male) 2.7

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