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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:26.2 nTPM
HPA Brain:115.8 nTPM
GTEx:26.2 nTPM
FANTOM5:10.2 Scaled Tags Per Million
Pig:44.1 nTPM
Mouse:41.4 nTPM
Allen mouse:8.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 73.4
2019 Male, age 18, unknown 110.4
1827 Male, age 72, unknown 107.6
2828 Female, age 72, unknown 104.5
2666 Male, age 74, left hemisphere 94.3
2586 Male, age 75, left hemisphere 74.3
2219 Male, age 76, both hemispheres 72.7
2411 Female, age 72, unknown 47.8
1833 Male, age 53, unknown 42.7
1870 Female, age 42, unknown 41.6
1830 Male, age 51, unknown 37.6
Dorsal raphe nucleus
nTPM: 55.1
2298 Female, age 72, unknown 76.5
1828 Male, age 53, unknown 56.6
2750 Male, age 76, both hemispheres 48.0
2016 Female, age 72, unknown 47.7
2047 Male, age 72, unknown 46.7
Inferior colliculus
nTPM: 56.3
2097 Female, age 72, unknown 64.8
1890 Male, age 53, unknown 55.0
1848 Female, age 42, unknown 54.3
2849 Male, age 72, unknown 51.2
Median raphe nucleus
nTPM: 60.7
2220 Male, age 76, midline 60.7
Periaquaductal grey, anterior
nTPM: 84.4
1795 Male, age 51, unknown 111.5
2502 Female, age 75, unknown 89.3
1947 Male, age 18, unknown 52.5
Periaquaductal grey, dorsal
nTPM: 80.4
2850 Male, age 76, both hemispheres 103.5
1831 Male, age 72, unknown 88.3
1840 Male, age 53, unknown 70.0
2464 Female, age 72, unknown 59.9
Periaquaductal grey, lateral
nTPM: 71.4
2140 Male, age 76, both hemispheres 84.4
2272 Male, age 74, both hemispheres 68.5
2053 Male, age 18, unknown 61.2
Pretectal area
nTPM: 115.8
1816 Male, age 51, unknown 215.7
1944 Female, age 72, unknown 210.2
2007 Male, age 72, unknown 176.7
1817 Female, age 42, unknown 167.1
1815 Male, age 53, unknown 150.5
2667 Female, age 75, unknown 82.6
2273 Male, age 74, both hemispheres 62.1
2224 Female, age 72, unknown 58.7
2316 Male, age 76, right hemisphere 51.4
2407 Male, age 75, both hemispheres 49.9
2825 Male, age 18, unknown 49.5
Red nucleus
nTPM: 51.4
2785 Male, age 18, unknown 119.7
2588 Male, age 74, left hemisphere 61.1
2584 Male, age 75, left hemisphere 60.3
2503 Female, age 72, unknown 50.0
1904 Male, age 53, unknown 43.3
1954 Female, age 42, unknown 43.3
2823 Male, age 76, right hemisphere 42.2
2725 Female, age 75, unknown 41.4
1821 Female, age 72, unknown 40.3
2769 Male, age 72, unknown 39.0
1865 Male, age 51, unknown 38.3
2227 Male, age 72, unknown 38.0
Substantia nigra
nTPM: 71.2
1889 Female, age 72, unknown 127.2
2665 Male, age 74, both hemispheres 115.2
1916 Female, age 42, unknown 85.2
1941 Male, age 53, unknown 80.6
1851 Male, age 51, unknown 73.8
2583 Male, age 75, right hemisphere 55.1
2590 Female, age 75, unknown 47.0
2699 Male, age 18, unknown 44.2
2241 Male, age 72, unknown 42.3
2409 Female, age 72, unknown 41.9
Superior colliculus
nTPM: 94.8
2087 Female, age 72, unknown 178.0
2668 Female, age 75, unknown 151.2
2261 Male, age 18, unknown 112.2
1796 Male, age 53, unknown 104.9
1913 Female, age 42, unknown 84.3
1995 Male, age 72, unknown 83.7
2664 Male, age 75, both hemispheres 78.4
1895 Male, age 76, right hemisphere 53.9
2587 Male, age 74, left hemisphere 53.0
1839 Male, age 51, unknown 48.8
Ventral tegmental area
nTPM: 56.0
2218 Male, age 76, both hemispheres 71.7
2410 Female, age 72, unknown 66.6
1942 Male, age 51, unknown 62.9
1915 Female, age 42, unknown 60.2
2021 Male, age 53, unknown 45.6
2223 Female, age 72, unknown 29.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 26.2
Samples: 139

Max nTPM: 86.8
Min nTPM: 2.5
Std nTPM: 17.2
Median nTPM: 21.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 86.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 72.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 69.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 68.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 65.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 65.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 63.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 60.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 58.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 56.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 56.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 55.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 54.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 53.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 53.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 51.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 51.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 49.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 49.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 48.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 48.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 46.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 43.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 43.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 43.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 39.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 38.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 38.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 36.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 36.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 36.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 36.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 35.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 35.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 35.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 34.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 34.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 34.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 34.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 32.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 32.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 32.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 32.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 31.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 31.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 29.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 29.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 29.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 29.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 28.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 28.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 28.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 27.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 26.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 25.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 25.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 25.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 25.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 25.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 25.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 24.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 22.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 22.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 22.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 22.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 22.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 22.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 21.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 21.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 21.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 20.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 20.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 19.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 18.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 18.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 18.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 17.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 17.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 17.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 17.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 17.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 17.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 17.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 16.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 16.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 16.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 16.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 16.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 16.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 15.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 15.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 15.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 14.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 14.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 14.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 14.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 14.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 14.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 13.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 13.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 13.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 13.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 13.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 13.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 12.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 12.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 12.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 11.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 11.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 10.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 10.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 10.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 10.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 10.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 9.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 9.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 9.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 9.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 8.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 8.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 7.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 7.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 6.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 6.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 6.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 5.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 4.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 4.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 4.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

10.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 10.2
FF:10158-103A5 76 years, female 10.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 25.2
Samples: 4

Max nTPM: 34.4
Min nTPM: 14.4
Sample A Female 30.6
Sample B Female 21.5
Sample C Male 34.4
Sample D Male 14.4
Midbrain
nTPM: 41.1
Samples: 4

Max nTPM: 83.1
Min nTPM: 15.1
Sample A Female 15.1
Sample B Female 25.0
Sample C Male 83.1
Sample D Male 41.3
Periaqueductal gray
nTPM: 26.0
Samples: 3

Max nTPM: 31.8
Min nTPM: 21.6
Sample B Female 24.7
Sample C Male 31.8
Sample D Male 21.6
Superior colliculi
nTPM: 44.2
Samples: 4

Max nTPM: 57.7
Min nTPM: 32.0
Sample A Female 32.0
Sample B Female 46.1
Sample C Male 57.7
Sample D Male 40.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 41.5
Samples: 4

Max nTPM: 46.9
Min nTPM: 35.8
Sample A Male 46.9
Sample B Male 35.8
Sample C Female 39.3
Sample D Female 43.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.6
68845371 Antisense, RP_050224_01_F08, Mouse strain C57BL/6J (56 days, male) 8.6

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