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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:77.6 nTPM
HPA Brain:222.4 nTPM
GTEx:77.6 nTPM
FANTOM5:139.1 Scaled Tags Per Million
Pig:112.1 nTPM
Mouse:31.1 nTPM
Allen mouse:11.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

222.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 204.8
2586 Male, age 75, left hemisphere 303.2
2666 Male, age 74, left hemisphere 248.2
2828 Female, age 72, unknown 241.2
1827 Male, age 72, unknown 209.3
2219 Male, age 76, both hemispheres 204.7
1833 Male, age 53, unknown 197.7
1870 Female, age 42, unknown 181.1
1830 Male, age 51, unknown 178.9
2019 Male, age 18, unknown 144.5
2411 Female, age 72, unknown 139.4
Dorsal raphe nucleus
nTPM: 158.1
1828 Male, age 53, unknown 185.5
2016 Female, age 72, unknown 167.6
2047 Male, age 72, unknown 163.8
2750 Male, age 76, both hemispheres 137.5
2298 Female, age 72, unknown 136.0
Inferior colliculus
nTPM: 208.7
2849 Male, age 72, unknown 295.5
1848 Female, age 42, unknown 202.8
1890 Male, age 53, unknown 184.2
2097 Female, age 72, unknown 152.1
Median raphe nucleus
nTPM: 187.8
2220 Male, age 76, midline 187.8
Periaquaductal grey, anterior
nTPM: 214.1
1947 Male, age 18, unknown 224.2
1795 Male, age 51, unknown 215.4
2502 Female, age 75, unknown 202.7
Periaquaductal grey, dorsal
nTPM: 222.4
2850 Male, age 76, both hemispheres 301.6
1840 Male, age 53, unknown 209.2
1831 Male, age 72, unknown 193.6
2464 Female, age 72, unknown 185.3
Periaquaductal grey, lateral
nTPM: 204.6
2140 Male, age 76, both hemispheres 253.7
2053 Male, age 18, unknown 190.3
2272 Male, age 74, both hemispheres 169.7
Pretectal area
nTPM: 193.7
2407 Male, age 75, both hemispheres 229.9
2825 Male, age 18, unknown 225.7
1816 Male, age 51, unknown 211.7
1817 Female, age 42, unknown 206.4
1815 Male, age 53, unknown 196.3
2667 Female, age 75, unknown 193.4
1944 Female, age 72, unknown 183.3
2007 Male, age 72, unknown 179.9
2316 Male, age 76, right hemisphere 174.7
2224 Female, age 72, unknown 169.1
2273 Male, age 74, both hemispheres 160.4
Red nucleus
nTPM: 178.9
2584 Male, age 75, left hemisphere 205.8
2725 Female, age 75, unknown 199.5
2588 Male, age 74, left hemisphere 196.8
2769 Male, age 72, unknown 191.9
2227 Male, age 72, unknown 188.5
2823 Male, age 76, right hemisphere 184.0
2503 Female, age 72, unknown 171.3
1954 Female, age 42, unknown 170.0
1865 Male, age 51, unknown 167.6
2785 Male, age 18, unknown 162.4
1904 Male, age 53, unknown 156.9
1821 Female, age 72, unknown 152.0
Substantia nigra
nTPM: 170.2
2699 Male, age 18, unknown 223.7
2665 Male, age 74, both hemispheres 207.4
1916 Female, age 42, unknown 188.0
2583 Male, age 75, right hemisphere 178.3
1941 Male, age 53, unknown 170.0
1851 Male, age 51, unknown 166.3
1889 Female, age 72, unknown 164.7
2590 Female, age 75, unknown 155.2
2241 Male, age 72, unknown 125.1
2409 Female, age 72, unknown 123.6
Superior colliculus
nTPM: 199.8
2664 Male, age 75, both hemispheres 310.5
1796 Male, age 53, unknown 207.5
1839 Male, age 51, unknown 206.2
2668 Female, age 75, unknown 199.2
2261 Male, age 18, unknown 192.3
2587 Male, age 74, left hemisphere 179.8
1913 Female, age 42, unknown 178.7
2087 Female, age 72, unknown 177.7
1995 Male, age 72, unknown 174.3
1895 Male, age 76, right hemisphere 172.3
Ventral tegmental area
nTPM: 166.2
2223 Female, age 72, unknown 176.4
2218 Male, age 76, both hemispheres 172.4
1942 Male, age 51, unknown 170.6
2021 Male, age 53, unknown 168.8
1915 Female, age 42, unknown 168.1
2410 Female, age 72, unknown 140.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 77.6
Samples: 139

Max nTPM: 156.7
Min nTPM: 47.8
Std nTPM: 16.7
Median nTPM: 75.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 156.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 129.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 123.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 123.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 120.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 113.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 106.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 106.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 106.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 104.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 99.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 97.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 97.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 96.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 96.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 95.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 95.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 94.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 94.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 92.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 92.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 91.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 90.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 90.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 89.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 89.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 89.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 88.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 87.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 87.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 86.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 86.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 85.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 85.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 85.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 85.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 85.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 85.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 85.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 84.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 83.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 83.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 83.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 83.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 82.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 82.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 82.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 82.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 81.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 81.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 81.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 81.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 80.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 80.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 79.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 79.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 79.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 79.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 78.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 77.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 77.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 77.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 76.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 75.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 75.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 75.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 75.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 75.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 75.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 74.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 74.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 74.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 74.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 73.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 73.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 73.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 72.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 72.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 72.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 72.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 72.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 71.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 71.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 70.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 70.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 70.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 70.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 69.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 69.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 69.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 69.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 68.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 68.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 68.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 68.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 68.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 68.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 67.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 67.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 66.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 66.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 65.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 65.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 65.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 65.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 65.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 64.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 63.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 63.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 63.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 63.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 63.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 63.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 62.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 62.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 62.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 62.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 61.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 61.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 60.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 59.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 59.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 56.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 55.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 55.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 54.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 54.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 54.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 53.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 51.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 49.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

139.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 139.1
FF:10158-103A5 76 years, female 139.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

112.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 83.6
Samples: 4

Max nTPM: 99.3
Min nTPM: 73.8
Sample A Female 82.3
Sample B Female 73.8
Sample C Male 99.3
Sample D Male 78.9
Midbrain
nTPM: 106.5
Samples: 4

Max nTPM: 139.0
Min nTPM: 82.1
Sample A Female 84.2
Sample B Female 82.1
Sample C Male 139.0
Sample D Male 120.8
Periaqueductal gray
nTPM: 90.1
Samples: 3

Max nTPM: 99.5
Min nTPM: 84.3
Sample B Female 84.3
Sample C Male 99.5
Sample D Male 86.5
Superior colliculi
nTPM: 112.1
Samples: 4

Max nTPM: 141.1
Min nTPM: 73.7
Sample A Female 112.7
Sample B Female 73.7
Sample C Male 120.9
Sample D Male 141.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

31.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 31.1
Samples: 4

Max nTPM: 34.9
Min nTPM: 28.2
Sample A Male 34.9
Sample B Male 28.2
Sample C Female 30.1
Sample D Female 31.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.1
68911027 Antisense, RP_050203_02_G07, Mouse strain C57BL/6J (56 days, male) 11.1

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