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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:20.9 nTPM
HPA Brain:87.1 nTPM
GTEx:20.9 nTPM
FANTOM5:87.8 Scaled Tags Per Million
Pig:45.5 nTPM
Mouse:16.5 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

87.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 48.1
2586 Male, age 75, left hemisphere 68.8
2828 Female, age 72, unknown 67.7
1870 Female, age 42, unknown 60.9
1827 Male, age 72, unknown 53.8
2666 Male, age 74, left hemisphere 53.1
1833 Male, age 53, unknown 45.5
1830 Male, age 51, unknown 43.7
2411 Female, age 72, unknown 39.8
2219 Male, age 76, both hemispheres 25.3
2019 Male, age 18, unknown 22.7
Dorsal raphe nucleus
nTPM: 66.7
2016 Female, age 72, unknown 87.5
1828 Male, age 53, unknown 70.9
2047 Male, age 72, unknown 66.4
2298 Female, age 72, unknown 63.2
2750 Male, age 76, both hemispheres 45.4
Inferior colliculus
nTPM: 56.1
1848 Female, age 42, unknown 68.5
2849 Male, age 72, unknown 60.1
1890 Male, age 53, unknown 49.5
2097 Female, age 72, unknown 46.5
Median raphe nucleus
nTPM: 52.2
2220 Male, age 76, midline 52.2
Periaquaductal grey, anterior
nTPM: 61.4
1947 Male, age 18, unknown 67.7
1795 Male, age 51, unknown 67.5
2502 Female, age 75, unknown 49.0
Periaquaductal grey, dorsal
nTPM: 73.9
2850 Male, age 76, both hemispheres 92.3
1831 Male, age 72, unknown 74.0
1840 Male, age 53, unknown 73.0
2464 Female, age 72, unknown 56.2
Periaquaductal grey, lateral
nTPM: 87.1
2053 Male, age 18, unknown 106.2
2140 Male, age 76, both hemispheres 94.8
2272 Male, age 74, both hemispheres 60.3
Pretectal area
nTPM: 56.3
2825 Male, age 18, unknown 85.3
2273 Male, age 74, both hemispheres 77.7
2224 Female, age 72, unknown 69.9
2316 Male, age 76, right hemisphere 62.6
2667 Female, age 75, unknown 59.6
1944 Female, age 72, unknown 56.0
2407 Male, age 75, both hemispheres 47.8
1817 Female, age 42, unknown 44.1
1815 Male, age 53, unknown 43.2
1816 Male, age 51, unknown 42.7
2007 Male, age 72, unknown 29.9
Red nucleus
nTPM: 44.7
2725 Female, age 75, unknown 62.0
1954 Female, age 42, unknown 55.1
2769 Male, age 72, unknown 50.1
2503 Female, age 72, unknown 49.8
2227 Male, age 72, unknown 48.4
2823 Male, age 76, right hemisphere 47.3
1865 Male, age 51, unknown 43.7
1821 Female, age 72, unknown 42.1
1904 Male, age 53, unknown 41.1
2588 Male, age 74, left hemisphere 40.4
2584 Male, age 75, left hemisphere 33.1
2785 Male, age 18, unknown 23.5
Substantia nigra
nTPM: 52.6
2699 Male, age 18, unknown 93.0
1916 Female, age 42, unknown 62.6
2409 Female, age 72, unknown 52.4
1851 Male, age 51, unknown 51.6
2590 Female, age 75, unknown 49.4
1889 Female, age 72, unknown 45.2
1941 Male, age 53, unknown 45.0
2241 Male, age 72, unknown 44.9
2583 Male, age 75, right hemisphere 44.3
2665 Male, age 74, both hemispheres 37.2
Superior colliculus
nTPM: 55.5
1796 Male, age 53, unknown 67.4
1995 Male, age 72, unknown 66.2
2664 Male, age 75, both hemispheres 63.8
1913 Female, age 42, unknown 63.7
1839 Male, age 51, unknown 56.2
2587 Male, age 74, left hemisphere 52.9
2087 Female, age 72, unknown 49.4
2261 Male, age 18, unknown 49.2
2668 Female, age 75, unknown 44.6
1895 Male, age 76, right hemisphere 41.6
Ventral tegmental area
nTPM: 54.5
2021 Male, age 53, unknown 66.9
1942 Male, age 51, unknown 60.8
1915 Female, age 42, unknown 58.4
2218 Male, age 76, both hemispheres 55.3
2410 Female, age 72, unknown 46.7
2223 Female, age 72, unknown 38.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 20.9
Samples: 139

Max nTPM: 76.8
Min nTPM: 1.3
Std nTPM: 13.5
Median nTPM: 17.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 76.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 74.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 65.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 60.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 57.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 54.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 48.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 47.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 46.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 46.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 45.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 39.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 36.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 36.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 35.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 34.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 33.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 33.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 32.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 32.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 32.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 30.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 29.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 29.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 29.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 28.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 28.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 28.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 28.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 27.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 27.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 27.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 27.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 27.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 26.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 24.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 24.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 24.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 23.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 23.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 23.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 23.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 23.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 22.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 22.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 22.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 22.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 21.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 21.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 21.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 20.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 20.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 20.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 20.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 20.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 18.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 18.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 18.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 18.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 18.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 18.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 18.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 18.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 18.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 18.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 18.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 18.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 17.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 17.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 17.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 17.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 17.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 17.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 17.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 16.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 16.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 15.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 15.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 14.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 14.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 14.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 14.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 14.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 14.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 14.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 14.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 14.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 13.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 13.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 13.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 13.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 13.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 13.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 13.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 12.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 12.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 12.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 12.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 12.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 12.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 12.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 12.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 11.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 11.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 11.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 11.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 11.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 11.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 11.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 11.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 10.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 10.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 10.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 10.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 10.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 10.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 9.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 9.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 9.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 9.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 8.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 8.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 8.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 7.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 7.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 6.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 5.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 5.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 5.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 4.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 4.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 4.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 4.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 3.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

87.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 87.8
FF:10158-103A5 76 years, female 87.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 35.2
Samples: 4

Max nTPM: 38.1
Min nTPM: 31.7
Sample A Female 34.6
Sample B Female 31.7
Sample C Male 36.5
Sample D Male 38.1
Midbrain
nTPM: 40.3
Samples: 4

Max nTPM: 68.7
Min nTPM: 26.8
Sample A Female 68.7
Sample B Female 33.2
Sample C Male 32.6
Sample D Male 26.8
Periaqueductal gray
nTPM: 45.5
Samples: 3

Max nTPM: 46.9
Min nTPM: 43.0
Sample B Female 43.0
Sample C Male 46.5
Sample D Male 46.9
Superior colliculi
nTPM: 27.7
Samples: 4

Max nTPM: 32.2
Min nTPM: 17.5
Sample A Female 29.6
Sample B Female 17.5
Sample C Male 31.6
Sample D Male 32.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 16.6
Samples: 4

Max nTPM: 18.5
Min nTPM: 14.2
Sample A Male 18.5
Sample B Male 18.2
Sample C Female 14.2
Sample D Female 15.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
71249068 Antisense, RP_050407_03_H09, Mouse strain C57BL/6J (56 days, male) 0.4
69290417 Antisense, RP_050407_03_H09, Mouse strain C57BL/6J (56 days, male) 0.2

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