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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:380.6 nTPM
HPA Brain:167.6 nTPM
GTEx:380.6 nTPM
FANTOM5:146.7 Scaled Tags Per Million
Pig:331.3 nTPM
Mouse:509.7 nTPM
Allen mouse:6.7 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

167.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 127.3
2019 Male, age 18, unknown 169.6
2411 Female, age 72, unknown 152.7
1870 Female, age 42, unknown 149.2
1827 Male, age 72, unknown 141.7
2219 Male, age 76, both hemispheres 119.3
2666 Male, age 74, left hemisphere 112.0
2828 Female, age 72, unknown 111.4
1833 Male, age 53, unknown 110.7
2586 Male, age 75, left hemisphere 103.5
1830 Male, age 51, unknown 103.4
Dorsal raphe nucleus
nTPM: 142.0
2298 Female, age 72, unknown 195.8
1828 Male, age 53, unknown 148.1
2047 Male, age 72, unknown 132.4
2750 Male, age 76, both hemispheres 128.1
2016 Female, age 72, unknown 105.7
Inferior colliculus
nTPM: 154.5
2097 Female, age 72, unknown 224.1
1890 Male, age 53, unknown 174.5
1848 Female, age 42, unknown 127.4
2849 Male, age 72, unknown 91.9
Median raphe nucleus
nTPM: 115.2
2220 Male, age 76, midline 115.2
Periaquaductal grey, anterior
nTPM: 133.2
1947 Male, age 18, unknown 144.2
2502 Female, age 75, unknown 128.0
1795 Male, age 51, unknown 127.3
Periaquaductal grey, dorsal
nTPM: 108.4
1831 Male, age 72, unknown 114.8
1840 Male, age 53, unknown 110.5
2464 Female, age 72, unknown 110.4
2850 Male, age 76, both hemispheres 97.9
Periaquaductal grey, lateral
nTPM: 111.9
2272 Male, age 74, both hemispheres 126.5
2053 Male, age 18, unknown 120.8
2140 Male, age 76, both hemispheres 88.4
Pretectal area
nTPM: 153.9
2007 Male, age 72, unknown 216.1
1816 Male, age 51, unknown 208.7
1817 Female, age 42, unknown 192.4
1944 Female, age 72, unknown 180.5
1815 Male, age 53, unknown 164.9
2224 Female, age 72, unknown 153.6
2667 Female, age 75, unknown 138.3
2273 Male, age 74, both hemispheres 128.2
2316 Male, age 76, right hemisphere 116.4
2825 Male, age 18, unknown 105.7
2407 Male, age 75, both hemispheres 88.0
Red nucleus
nTPM: 167.6
1821 Female, age 72, unknown 269.7
2725 Female, age 75, unknown 201.9
2503 Female, age 72, unknown 189.5
2785 Male, age 18, unknown 165.4
1865 Male, age 51, unknown 164.3
1904 Male, age 53, unknown 161.5
2227 Male, age 72, unknown 156.5
2769 Male, age 72, unknown 152.3
2823 Male, age 76, right hemisphere 150.6
1954 Female, age 42, unknown 143.4
2588 Male, age 74, left hemisphere 142.0
2584 Male, age 75, left hemisphere 113.5
Substantia nigra
nTPM: 159.3
1916 Female, age 42, unknown 210.8
1889 Female, age 72, unknown 210.2
1851 Male, age 51, unknown 192.6
2241 Male, age 72, unknown 188.8
1941 Male, age 53, unknown 157.8
2409 Female, age 72, unknown 143.6
2665 Male, age 74, both hemispheres 134.9
2699 Male, age 18, unknown 125.3
2590 Female, age 75, unknown 116.7
2583 Male, age 75, right hemisphere 112.7
Superior colliculus
nTPM: 128.9
2668 Female, age 75, unknown 152.8
2587 Male, age 74, left hemisphere 148.1
2087 Female, age 72, unknown 144.0
1895 Male, age 76, right hemisphere 143.4
1796 Male, age 53, unknown 136.8
2261 Male, age 18, unknown 136.6
1913 Female, age 42, unknown 126.7
1995 Male, age 72, unknown 112.6
1839 Male, age 51, unknown 102.7
2664 Male, age 75, both hemispheres 85.4
Ventral tegmental area
nTPM: 149.4
1915 Female, age 42, unknown 171.1
2223 Female, age 72, unknown 169.9
2410 Female, age 72, unknown 169.9
2218 Male, age 76, both hemispheres 146.3
1942 Male, age 51, unknown 131.7
2021 Male, age 53, unknown 107.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

380.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 380.6
Samples: 139

Max nTPM: 1044.7
Min nTPM: 204.8
Std nTPM: 126.3
Median nTPM: 359.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1044.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 903.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 769.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 721.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 661.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 619.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 595.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 593.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 577.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 567.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 558.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 555.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 552.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 547.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 544.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 542.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 538.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 494.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 482.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 480.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 480.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 461.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 459.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 448.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 446.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 444.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 441.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 438.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 435.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 434.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 431.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 425.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 425.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 424.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 423.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 422.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 419.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 419.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 417.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 417.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 410.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 409.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 409.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 407.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 404.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 401.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 400.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 400.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 396.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 394.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 391.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 391.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 390.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 390.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 389.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 389.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 384.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 382.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 381.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 378.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 376.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 373.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 372.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 369.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 362.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 360.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 359.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 359.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 359.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 359.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 357.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 356.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 356.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 354.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 352.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 352.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 351.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 344.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 342.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 340.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 337.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 335.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 332.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 326.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 325.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 324.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 323.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 323.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 323.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 322.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 318.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 317.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 316.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 315.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 314.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 314.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 314.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 314.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 310.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 310.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 308.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 307.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 306.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 306.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 303.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 302.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 301.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 300.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 298.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 297.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 296.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 284.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 281.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 280.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 279.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 278.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 273.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 271.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 269.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 264.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 258.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 257.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 254.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 252.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 252.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 250.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 250.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 247.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 243.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 242.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 237.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 235.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 235.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 232.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 227.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 223.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 222.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 218.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 204.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

146.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 146.7
FF:10158-103A5 76 years, female 146.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

331.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 255.4
Samples: 4

Max nTPM: 387.9
Min nTPM: 178.0
Sample A Female 387.9
Sample B Female 220.6
Sample C Male 235.1
Sample D Male 178.0
Midbrain
nTPM: 273.6
Samples: 4

Max nTPM: 339.5
Min nTPM: 224.2
Sample A Female 272.8
Sample B Female 224.2
Sample C Male 339.5
Sample D Male 257.9
Periaqueductal gray
nTPM: 161.3
Samples: 3

Max nTPM: 176.3
Min nTPM: 141.7
Sample B Female 176.3
Sample C Male 166.0
Sample D Male 141.7
Superior colliculi
nTPM: 331.3
Samples: 4

Max nTPM: 432.4
Min nTPM: 236.7
Sample A Female 341.7
Sample B Female 314.3
Sample C Male 432.4
Sample D Male 236.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

509.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 509.7
Samples: 4

Max nTPM: 531.9
Min nTPM: 496.9
Sample A Male 531.9
Sample B Male 496.9
Sample C Female 500.5
Sample D Female 509.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.7
68301443 Antisense, RP_041130_01_C06, Mouse strain C57BL/6J (56 days, male) 6.7

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