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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:102.5 nTPM
HPA Brain:89.5 nTPM
GTEx:102.5 nTPM
FANTOM5:220.0 Scaled Tags Per Million
Pig:143.4 nTPM
Mouse:183.9 nTPM
Allen mouse:8.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

89.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 59.9
1827 Male, age 72, unknown 73.6
2019 Male, age 18, unknown 70.1
2411 Female, age 72, unknown 66.8
1870 Female, age 42, unknown 66.4
2828 Female, age 72, unknown 64.3
1833 Male, age 53, unknown 62.9
2219 Male, age 76, both hemispheres 61.4
1830 Male, age 51, unknown 54.6
2666 Male, age 74, left hemisphere 48.0
2586 Male, age 75, left hemisphere 30.6
Dorsal raphe nucleus
nTPM: 78.1
2298 Female, age 72, unknown 95.1
2750 Male, age 76, both hemispheres 79.8
1828 Male, age 53, unknown 79.2
2047 Male, age 72, unknown 75.6
2016 Female, age 72, unknown 61.1
Inferior colliculus
nTPM: 65.0
2097 Female, age 72, unknown 74.6
1848 Female, age 42, unknown 65.6
1890 Male, age 53, unknown 62.2
2849 Male, age 72, unknown 57.5
Median raphe nucleus
nTPM: 89.5
2220 Male, age 76, midline 89.5
Periaquaductal grey, anterior
nTPM: 63.8
1947 Male, age 18, unknown 76.5
1795 Male, age 51, unknown 65.3
2502 Female, age 75, unknown 49.5
Periaquaductal grey, dorsal
nTPM: 65.1
2850 Male, age 76, both hemispheres 85.3
1840 Male, age 53, unknown 60.7
1831 Male, age 72, unknown 57.3
2464 Female, age 72, unknown 57.2
Periaquaductal grey, lateral
nTPM: 77.2
2272 Male, age 74, both hemispheres 90.5
2140 Male, age 76, both hemispheres 85.0
2053 Male, age 18, unknown 56.1
Pretectal area
nTPM: 78.6
2667 Female, age 75, unknown 95.8
2273 Male, age 74, both hemispheres 90.1
1944 Female, age 72, unknown 87.1
1816 Male, age 51, unknown 85.0
1817 Female, age 42, unknown 82.9
2007 Male, age 72, unknown 81.9
2224 Female, age 72, unknown 81.0
1815 Male, age 53, unknown 73.8
2316 Male, age 76, right hemisphere 67.0
2825 Male, age 18, unknown 60.3
2407 Male, age 75, both hemispheres 59.8
Red nucleus
nTPM: 69.5
2725 Female, age 75, unknown 97.1
1821 Female, age 72, unknown 86.4
2503 Female, age 72, unknown 76.7
1954 Female, age 42, unknown 70.1
1904 Male, age 53, unknown 67.7
1865 Male, age 51, unknown 67.5
2823 Male, age 76, right hemisphere 67.4
2769 Male, age 72, unknown 66.9
2785 Male, age 18, unknown 66.8
2227 Male, age 72, unknown 65.8
2588 Male, age 74, left hemisphere 51.1
2584 Male, age 75, left hemisphere 50.9
Substantia nigra
nTPM: 80.7
1916 Female, age 42, unknown 115.1
1851 Male, age 51, unknown 90.3
1889 Female, age 72, unknown 89.9
1941 Male, age 53, unknown 88.6
2241 Male, age 72, unknown 88.4
2699 Male, age 18, unknown 81.7
2409 Female, age 72, unknown 74.1
2590 Female, age 75, unknown 70.4
2665 Male, age 74, both hemispheres 60.2
2583 Male, age 75, right hemisphere 48.3
Superior colliculus
nTPM: 62.0
2087 Female, age 72, unknown 77.2
1895 Male, age 76, right hemisphere 76.3
2587 Male, age 74, left hemisphere 76.0
2261 Male, age 18, unknown 70.5
1796 Male, age 53, unknown 69.4
1913 Female, age 42, unknown 58.9
1995 Male, age 72, unknown 55.3
1839 Male, age 51, unknown 55.2
2668 Female, age 75, unknown 48.7
2664 Male, age 75, both hemispheres 32.2
Ventral tegmental area
nTPM: 76.8
2218 Male, age 76, both hemispheres 89.2
2410 Female, age 72, unknown 88.2
1915 Female, age 42, unknown 84.4
1942 Male, age 51, unknown 68.9
2223 Female, age 72, unknown 67.9
2021 Male, age 53, unknown 62.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

102.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 102.5
Samples: 139

Max nTPM: 193.3
Min nTPM: 66.0
Std nTPM: 20.6
Median nTPM: 99.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 193.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 155.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 154.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 145.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 143.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 141.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 141.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 138.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 138.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 136.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 135.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 135.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 133.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 133.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 133.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 132.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 129.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 129.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 128.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 127.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 126.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 122.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 121.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 119.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 118.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 117.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 117.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 117.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 116.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 116.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 116.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 115.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 115.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 114.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 114.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 112.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 112.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 111.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 110.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 110.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 110.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 110.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 108.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 108.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 108.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 108.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 107.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 107.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 107.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 106.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 106.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 106.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 103.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 103.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 103.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 101.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 101.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 101.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 101.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 101.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 101.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 101.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 100.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 100.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 100.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 100.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 100.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 99.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 99.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 99.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 99.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 98.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 98.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 98.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 98.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 97.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 97.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 97.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 97.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 96.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 96.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 96.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 96.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 95.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 95.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 94.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 92.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 92.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 92.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 91.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 91.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 91.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 91.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 91.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 90.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 90.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 90.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 89.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 89.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 89.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 89.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 88.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 88.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 88.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 87.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 86.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 86.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 85.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 85.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 85.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 85.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 84.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 84.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 84.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 84.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 84.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 84.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 84.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 83.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 82.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 81.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 81.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 80.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 80.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 79.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 78.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 76.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 76.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 76.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 75.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 75.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 75.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 72.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 71.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 71.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 70.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 68.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 66.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

220.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 220.0
FF:10158-103A5 76 years, female 220.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

143.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 139.4
Samples: 4

Max nTPM: 164.1
Min nTPM: 113.6
Sample A Female 164.1
Sample B Female 113.6
Sample C Male 148.8
Sample D Male 131.0
Midbrain
nTPM: 141.8
Samples: 4

Max nTPM: 152.1
Min nTPM: 132.3
Sample A Female 150.4
Sample B Female 132.3
Sample C Male 152.1
Sample D Male 132.5
Periaqueductal gray
nTPM: 124.9
Samples: 3

Max nTPM: 133.7
Min nTPM: 113.8
Sample B Female 127.2
Sample C Male 133.7
Sample D Male 113.8
Superior colliculi
nTPM: 143.4
Samples: 4

Max nTPM: 159.6
Min nTPM: 120.9
Sample A Female 147.6
Sample B Female 120.9
Sample C Male 159.6
Sample D Male 145.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

183.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 183.9
Samples: 4

Max nTPM: 190.3
Min nTPM: 171.8
Sample A Male 171.8
Sample B Male 189.8
Sample C Female 190.3
Sample D Female 183.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.4
69735144 Antisense, RP_050503_02_B09, Mouse strain C57BL/6J (56 days, male) 8.4

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