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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
107.4
nTPM
HPA:
103.5
nTPM
GTEx:
107.4
nTPM
FANTOM5:
224.8
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA044564
Antibody HPA055841
Cholangiocytes
Not detected
Not detected
Hepatocytes
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
103.5
Female, age 60
Liver sample 21 nTPM: 108.6
Male, age 54
Liver sample 23 nTPM: 85.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 85.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 169.9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 86.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 90
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 129
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 102.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 101.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 76.6
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
107.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 107.4
Samples: 226
Max nTPM: 436.6
Min nTPM: 36.3
Std nTPM: 61.7
Median nTPM: 88.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
436.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
364.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
310.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
286.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
275.9
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
272.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
264.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
259.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
257.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
245.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
240.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
237.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
231.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
220.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
209.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
209.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
202.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
193.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
193.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
190.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
189.4
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
185.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
181.1
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
180.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
179.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
178.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
176.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
174.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
174.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
174.2
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
170.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
165.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
163.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
162.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
161.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
160.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
159.1
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
158.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
157.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
156.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
153.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
152.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
151.1
GTEX-X261-1726-SM-4PQYT
50-59 years, male
147.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
144.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
142.3
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
141.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
141.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
141.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
140.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
139.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
138.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
137.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
135.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
135.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
135.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
134.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
134.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
133.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
132.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
132.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
129.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
129.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
127.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
125.8
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
125.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
125.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
123.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
122.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
122.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
122.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
122.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
121.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
121.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
121.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
121.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
120.8
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
120.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
119.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
119.3
GTEX-S32W-1926-SM-4AD63
50-59 years, female
118.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
117.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
112.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
112.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
111.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
111.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
110.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
110.3
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
109.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
107.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
106.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
106.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
105.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
102.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
101.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
100.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
100.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
98.5
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
98.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
95.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
95.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
94.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
94.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
93.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
93.2
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
93.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
92.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
91.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
91.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
91.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
89.8
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
89.3
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
89.2
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
87.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
86.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
86.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
85.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
85.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
84.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
83.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
83.6
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
82.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
82.4
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
82.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
81.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
80.9
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
80.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
80.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
79.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
78.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
78.4
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
77.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
76.9
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
76.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
76.7
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
76.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
74.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
74.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
73.6
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
72.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
71.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
71.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
70.3
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
70.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
69.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
69.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
69.7
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
69.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
69.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
68.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
68.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
68.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
67.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
67.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
67.7
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
67.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
66.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
66.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
66.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
66.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
65.9
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
65.8
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
65.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
65.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
65.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
65.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
64.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
64.3
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
64.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
63.6
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
63.5
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
63.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
63.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
63.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
63.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
62.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
60.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
60.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
59.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
59.6
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
59.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
59.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
58.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
58.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
58.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
58.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
58.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
57.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
56.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
56.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
55.4
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
54.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
54.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
54.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
53.9
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
53.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
53.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
52.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
52.7
GTEX-14E7W-1526-SM-6871X
70-79 years, male
52.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
52.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
52.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
51.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
51.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
51.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
51.3
GTEX-QESD-2026-SM-447BI
20-29 years, male
48.7
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
48.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
48.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
47.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
47.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
46.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
46.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
45.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
44.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
43.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
43.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
42.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
42.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
42.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
41.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
40.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
39.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
38.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
36.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
