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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:13.8 nTPM
HPA Brain:144.2 nTPM
GTEx:13.8 nTPM
FANTOM5:148.8 Scaled Tags Per Million
Pig:138.0 nTPM
Mouse:9.3 nTPM
Allen mouse:1.9 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

144.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 117.8
2586 Male, age 75, left hemisphere 177.6
2019 Male, age 18, unknown 138.3
1870 Female, age 42, unknown 126.6
2828 Female, age 72, unknown 125.7
1827 Male, age 72, unknown 118.1
1830 Male, age 51, unknown 113.5
1833 Male, age 53, unknown 110.1
2411 Female, age 72, unknown 104.6
2666 Male, age 74, left hemisphere 100.7
2219 Male, age 76, both hemispheres 62.9
Dorsal raphe nucleus
nTPM: 122.6
2016 Female, age 72, unknown 158.1
1828 Male, age 53, unknown 123.3
2298 Female, age 72, unknown 117.5
2047 Male, age 72, unknown 117.0
2750 Male, age 76, both hemispheres 97.2
Inferior colliculus
nTPM: 117.4
1848 Female, age 42, unknown 121.5
2097 Female, age 72, unknown 120.6
2849 Male, age 72, unknown 120.6
1890 Male, age 53, unknown 107.0
Median raphe nucleus
nTPM: 92.4
2220 Male, age 76, midline 92.4
Periaquaductal grey, anterior
nTPM: 132.4
2502 Female, age 75, unknown 164.7
1947 Male, age 18, unknown 121.3
1795 Male, age 51, unknown 111.1
Periaquaductal grey, dorsal
nTPM: 144.2
2850 Male, age 76, both hemispheres 172.6
1840 Male, age 53, unknown 161.8
2464 Female, age 72, unknown 131.7
1831 Male, age 72, unknown 110.9
Periaquaductal grey, lateral
nTPM: 129.6
2140 Male, age 76, both hemispheres 180.8
2053 Male, age 18, unknown 110.9
2272 Male, age 74, both hemispheres 97.1
Pretectal area
nTPM: 118.4
2316 Male, age 76, right hemisphere 135.1
2273 Male, age 74, both hemispheres 133.3
2667 Female, age 75, unknown 128.0
1817 Female, age 42, unknown 123.9
2224 Female, age 72, unknown 116.9
2007 Male, age 72, unknown 116.7
1944 Female, age 72, unknown 115.9
1815 Male, age 53, unknown 110.7
2407 Male, age 75, both hemispheres 110.5
1816 Male, age 51, unknown 108.0
2825 Male, age 18, unknown 103.7
Red nucleus
nTPM: 122.3
1954 Female, age 42, unknown 142.5
2503 Female, age 72, unknown 141.7
2785 Male, age 18, unknown 136.6
1821 Female, age 72, unknown 134.7
2769 Male, age 72, unknown 130.5
1904 Male, age 53, unknown 130.4
1865 Male, age 51, unknown 129.7
2227 Male, age 72, unknown 127.5
2588 Male, age 74, left hemisphere 122.4
2823 Male, age 76, right hemisphere 99.1
2725 Female, age 75, unknown 86.6
2584 Male, age 75, left hemisphere 85.4
Substantia nigra
nTPM: 111.5
2583 Male, age 75, right hemisphere 123.7
2699 Male, age 18, unknown 121.1
1851 Male, age 51, unknown 120.4
1941 Male, age 53, unknown 117.1
1889 Female, age 72, unknown 111.1
1916 Female, age 42, unknown 107.7
2590 Female, age 75, unknown 106.5
2241 Male, age 72, unknown 106.4
2409 Female, age 72, unknown 102.1
2665 Male, age 74, both hemispheres 98.9
Superior colliculus
nTPM: 122.6
2664 Male, age 75, both hemispheres 177.4
1995 Male, age 72, unknown 139.3
1839 Male, age 51, unknown 131.3
2668 Female, age 75, unknown 128.0
1913 Female, age 42, unknown 127.7
2261 Male, age 18, unknown 111.5
2587 Male, age 74, left hemisphere 106.9
1796 Male, age 53, unknown 106.5
2087 Female, age 72, unknown 106.2
1895 Male, age 76, right hemisphere 91.7
Ventral tegmental area
nTPM: 103.0
2410 Female, age 72, unknown 110.1
1915 Female, age 42, unknown 108.6
2021 Male, age 53, unknown 106.9
1942 Male, age 51, unknown 104.7
2218 Male, age 76, both hemispheres 99.5
2223 Female, age 72, unknown 88.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 13.8
Samples: 139

Max nTPM: 47.0
Min nTPM: 4.6
Std nTPM: 6.7
Median nTPM: 12.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 47.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 41.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 39.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 37.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 28.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 26.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 26.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 25.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 23.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 22.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 22.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 21.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 21.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 21.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 20.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 20.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 20.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 20.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 20.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 19.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 19.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 19.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 18.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 18.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 18.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 17.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 17.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 17.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 17.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 16.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 16.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 16.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 15.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 15.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 15.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 15.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 15.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 15.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 15.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 15.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 14.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 14.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 14.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 14.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 14.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 13.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 13.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 13.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 13.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 13.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 13.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 13.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 13.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 12.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 12.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 12.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 12.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 12.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 12.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 12.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 12.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 12.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 12.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 12.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 12.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 11.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 11.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 11.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 11.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 11.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 11.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 11.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 11.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 11.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 11.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 11.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 10.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 10.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 10.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 10.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 10.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 10.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 10.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 10.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 10.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 10.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 10.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 10.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 10.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 10.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 10.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 9.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 9.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 9.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 9.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 9.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 9.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 9.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 9.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 9.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 9.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 9.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 9.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 9.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 9.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 9.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 8.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 8.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 8.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 8.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 8.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 8.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 8.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 8.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 8.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 8.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 7.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 7.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 7.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 7.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 7.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 6.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 6.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 6.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 6.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 6.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 5.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 5.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 4.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

148.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 148.8
FF:10158-103A5 76 years, female 148.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

138.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 135.7
Samples: 4

Max nTPM: 158.3
Min nTPM: 115.7
Sample A Female 145.9
Sample B Female 115.7
Sample C Male 122.8
Sample D Male 158.3
Midbrain
nTPM: 138.0
Samples: 4

Max nTPM: 161.5
Min nTPM: 118.8
Sample A Female 138.3
Sample B Female 161.5
Sample C Male 133.3
Sample D Male 118.8
Periaqueductal gray
nTPM: 133.3
Samples: 3

Max nTPM: 143.9
Min nTPM: 114.2
Sample B Female 143.9
Sample C Male 141.9
Sample D Male 114.2
Superior colliculi
nTPM: 114.0
Samples: 4

Max nTPM: 136.6
Min nTPM: 68.8
Sample A Female 136.6
Sample B Female 68.8
Sample C Male 131.6
Sample D Male 118.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 9.3
Samples: 4

Max nTPM: 10.3
Min nTPM: 7.2
Sample A Male 7.2
Sample B Male 9.6
Sample C Female 10.1
Sample D Female 10.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.9
71016573 Antisense, RP_050725_03_A01, Mouse strain C57BL/6J (56 days, male) 3.1
68631966 Antisense, RP_050125_01_D11, Mouse strain C57BL/6J (56 days, male) 0.8

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