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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
195.7
nTPM
HPA:
195.7
nTPM
GTEx:
102.9
nTPM
FANTOM5:
163.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA036939
Antibody HPA036940
Cholangiocytes
Not detected
Not detected
Hepatocytes
High
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
195.7
Female, age 60
Liver sample 21 nTPM: 147.9
Male, age 54
Liver sample 23 nTPM: 99.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 176.4
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 214
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 226.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 216.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 204.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 229.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 217
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 224
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
102.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 102.9
Samples: 226
Max nTPM: 238.7
Min nTPM: 22.5
Std nTPM: 45.4
Median nTPM: 99.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
238.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
237.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
237.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
237.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
236.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
219.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
219.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
208.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
207.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
199.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
195.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
194.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
189.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
177.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
176.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
172.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
167.3
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
165.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
165.5
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
165.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
163.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
161.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
160.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
156.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
155.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
155.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
154.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
154.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
152.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
149.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
149.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
149.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
147.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
147.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
147.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
144.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
143.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
142.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
142.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
141.7
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
141.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
140.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
140.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
140.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
139.9
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
139.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
138.6
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
138.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
137.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
136.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
136.2
GTEX-18A7A-1526-SM-72D69
50-59 years, female
134.7
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
134.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
132.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
132.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
132.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
132.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
130.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
128.9
GTEX-18A66-2026-SM-7189C
60-69 years, male
128.1
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
126.0
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
125.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
125.0
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
124.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
124.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
123.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
122.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
122.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
121.5
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
121.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
120.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
119.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
118.4
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
117.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
116.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
116.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
116.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
115.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
114.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
113.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
113.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
113.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
113.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
112.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
112.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
112.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
111.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
111.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
110.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
110.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
110.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
109.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
109.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
109.1
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
108.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
107.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
107.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
106.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
106.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
106.3
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
105.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
105.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
104.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
102.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
102.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
101.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
101.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
101.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
101.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
101.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
100.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
99.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
99.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
99.0
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
97.9
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
97.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
96.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
96.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
96.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
96.0
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
95.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
94.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
92.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
90.8
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
90.8
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
90.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
90.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
89.6
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
88.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
88.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
88.0
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
86.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
85.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
85.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
84.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
83.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
83.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
83.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
82.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
82.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
81.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
80.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
80.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
80.1
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
79.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
79.6
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
79.1
GTEX-REY6-1226-SM-48FDR
60-69 years, male
79.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
78.8
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
78.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
77.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
77.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
77.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
76.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
76.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
76.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
75.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
75.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
74.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
74.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
73.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
73.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
73.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
72.2
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
71.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
69.5
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
68.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
68.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
67.0
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
66.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
66.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
66.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
66.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
65.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
65.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
65.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
65.2
GTEX-11ZUS-2526-SM-59872
30-39 years, male
64.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
64.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
63.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
63.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
63.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
62.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
62.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
62.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
62.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
59.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
59.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
57.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
57.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
56.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
56.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
56.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
55.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
55.8
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
55.5
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
55.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
55.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
55.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
53.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
53.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
53.9
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
52.6
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
51.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
49.7
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
46.3
GTEX-11GSP-0626-SM-5986T
60-69 years, female
46.0
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
46.0
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
45.9
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
45.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
45.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
45.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
44.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
44.2
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
43.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
42.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
37.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
37.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
35.0
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
32.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
32.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
30.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
29.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
28.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
24.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
22.5
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
