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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:34.1 nTPM
HPA Brain:117.6 nTPM
GTEx:34.1 nTPM
FANTOM5:65.0 Scaled Tags Per Million
Pig:113.3 nTPM
Mouse:319.2 nTPM
Allen mouse:8.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

117.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 89.2
1827 Male, age 72, unknown 117.3
2411 Female, age 72, unknown 108.3
2219 Male, age 76, both hemispheres 96.7
1870 Female, age 42, unknown 90.8
2666 Male, age 74, left hemisphere 88.8
2586 Male, age 75, left hemisphere 82.3
1833 Male, age 53, unknown 81.1
2019 Male, age 18, unknown 80.2
2828 Female, age 72, unknown 75.5
1830 Male, age 51, unknown 71.4
Dorsal raphe nucleus
nTPM: 101.1
2298 Female, age 72, unknown 140.2
2047 Male, age 72, unknown 107.7
2750 Male, age 76, both hemispheres 92.8
1828 Male, age 53, unknown 92.0
2016 Female, age 72, unknown 72.7
Inferior colliculus
nTPM: 100.6
2097 Female, age 72, unknown 122.4
1848 Female, age 42, unknown 100.5
2849 Male, age 72, unknown 91.8
1890 Male, age 53, unknown 87.7
Median raphe nucleus
nTPM: 117.6
2220 Male, age 76, midline 117.6
Periaquaductal grey, anterior
nTPM: 106.1
1947 Male, age 18, unknown 116.2
2502 Female, age 75, unknown 107.3
1795 Male, age 51, unknown 94.9
Periaquaductal grey, dorsal
nTPM: 88.9
1840 Male, age 53, unknown 107.2
2464 Female, age 72, unknown 85.5
1831 Male, age 72, unknown 85.2
2850 Male, age 76, both hemispheres 77.7
Periaquaductal grey, lateral
nTPM: 83.3
2053 Male, age 18, unknown 88.3
2272 Male, age 74, both hemispheres 87.4
2140 Male, age 76, both hemispheres 74.2
Pretectal area
nTPM: 99.1
1816 Male, age 51, unknown 132.0
2007 Male, age 72, unknown 119.0
1944 Female, age 72, unknown 114.7
2224 Female, age 72, unknown 107.3
1817 Female, age 42, unknown 103.2
1815 Male, age 53, unknown 98.4
2667 Female, age 75, unknown 96.7
2825 Male, age 18, unknown 91.6
2273 Male, age 74, both hemispheres 83.5
2407 Male, age 75, both hemispheres 74.8
2316 Male, age 76, right hemisphere 69.1
Red nucleus
nTPM: 68.4
1821 Female, age 72, unknown 88.5
2725 Female, age 75, unknown 87.2
2584 Male, age 75, left hemisphere 76.2
2785 Male, age 18, unknown 69.5
1954 Female, age 42, unknown 68.4
2588 Male, age 74, left hemisphere 67.8
2227 Male, age 72, unknown 65.1
2769 Male, age 72, unknown 62.8
1865 Male, age 51, unknown 60.9
2503 Female, age 72, unknown 59.0
2823 Male, age 76, right hemisphere 58.0
1904 Male, age 53, unknown 57.3
Substantia nigra
nTPM: 110.5
1916 Female, age 42, unknown 156.9
1941 Male, age 53, unknown 149.5
2241 Male, age 72, unknown 133.5
1889 Female, age 72, unknown 121.6
1851 Male, age 51, unknown 118.1
2409 Female, age 72, unknown 104.1
2665 Male, age 74, both hemispheres 89.6
2699 Male, age 18, unknown 80.4
2583 Male, age 75, right hemisphere 75.5
2590 Female, age 75, unknown 75.5
Superior colliculus
nTPM: 85.5
2261 Male, age 18, unknown 107.9
1895 Male, age 76, right hemisphere 99.5
2087 Female, age 72, unknown 99.0
1839 Male, age 51, unknown 91.4
2664 Male, age 75, both hemispheres 91.0
2668 Female, age 75, unknown 90.8
1796 Male, age 53, unknown 90.5
2587 Male, age 74, left hemisphere 79.4
1913 Female, age 42, unknown 58.3
1995 Male, age 72, unknown 47.3
Ventral tegmental area
nTPM: 102.8
2218 Male, age 76, both hemispheres 121.6
1915 Female, age 42, unknown 117.8
2410 Female, age 72, unknown 114.6
1942 Male, age 51, unknown 94.4
2021 Male, age 53, unknown 85.2
2223 Female, age 72, unknown 83.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

34.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 34.1
Samples: 139

Max nTPM: 143.4
Min nTPM: 9.7
Std nTPM: 22.6
Median nTPM: 26.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 143.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 132.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 100.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 77.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 74.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 73.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 72.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 67.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 66.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 65.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 64.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 62.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 62.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 61.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 57.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 56.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 55.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 54.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 53.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 52.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 50.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 48.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 48.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 48.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 47.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 47.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 47.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 46.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 46.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 46.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 45.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 45.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 44.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 42.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 42.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 41.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 41.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 41.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 40.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 38.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 38.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 38.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 37.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 36.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 35.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 34.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 34.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 33.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 33.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 33.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 33.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 33.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 32.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 32.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 31.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 30.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 30.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 30.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 29.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 29.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 29.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 28.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 27.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 26.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 26.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 25.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 24.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 24.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 23.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 23.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 23.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 23.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 22.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 22.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 22.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 22.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 22.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 22.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 21.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 21.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 21.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 21.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 20.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 20.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 20.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 19.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 19.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 19.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 19.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 19.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 18.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 18.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 18.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 18.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 18.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 18.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 18.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 17.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 17.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 17.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 17.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 17.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 17.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 17.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 16.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 16.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 16.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 16.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 15.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 15.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 15.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 15.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 15.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 15.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 15.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 14.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 14.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 14.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 14.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 14.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 13.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 13.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 13.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 12.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 12.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 12.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 12.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

65.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 65.0
FF:10158-103A5 76 years, female 65.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

113.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 88.8
Samples: 4

Max nTPM: 131.4
Min nTPM: 37.3
Sample A Female 131.4
Sample B Female 68.4
Sample C Male 118.1
Sample D Male 37.3
Midbrain
nTPM: 102.6
Samples: 4

Max nTPM: 139.3
Min nTPM: 57.0
Sample A Female 57.0
Sample B Female 83.9
Sample C Male 139.3
Sample D Male 130.2
Periaqueductal gray
nTPM: 84.9
Samples: 3

Max nTPM: 106.0
Min nTPM: 71.2
Sample B Female 77.4
Sample C Male 106.0
Sample D Male 71.2
Superior colliculi
nTPM: 113.3
Samples: 4

Max nTPM: 139.1
Min nTPM: 74.8
Sample A Female 135.6
Sample B Female 74.8
Sample C Male 139.1
Sample D Male 103.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

319.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 319.2
Samples: 4

Max nTPM: 332.6
Min nTPM: 308.8
Sample A Male 308.8
Sample B Male 332.6
Sample C Female 320.9
Sample D Female 314.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.9
74641315 Antisense, RP_060220_02_E02, Mouse strain C57BL/6J (56 days, male) 9.6
68546392 Antisense, RP_050120_02_D08, Mouse strain C57BL/6J (56 days, male) 8.3

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