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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:47.0 nTPM
HPA Brain:86.3 nTPM
GTEx:47.0 nTPM
FANTOM5:77.2 Scaled Tags Per Million
Pig:106.6 nTPM
Mouse:21.0 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 72.9
1830 Male, age 51, unknown 84.7
1870 Female, age 42, unknown 82.3
2019 Male, age 18, unknown 80.0
2586 Male, age 75, left hemisphere 76.8
1833 Male, age 53, unknown 73.3
2411 Female, age 72, unknown 72.4
1827 Male, age 72, unknown 70.2
2828 Female, age 72, unknown 68.1
2219 Male, age 76, both hemispheres 60.9
2666 Male, age 74, left hemisphere 60.3
Dorsal raphe nucleus
nTPM: 62.5
2750 Male, age 76, both hemispheres 74.4
2016 Female, age 72, unknown 69.8
1828 Male, age 53, unknown 65.8
2047 Male, age 72, unknown 57.1
2298 Female, age 72, unknown 45.1
Inferior colliculus
nTPM: 63.6
1848 Female, age 42, unknown 74.2
2849 Male, age 72, unknown 64.2
1890 Male, age 53, unknown 60.4
2097 Female, age 72, unknown 55.6
Median raphe nucleus
nTPM: 51.9
2220 Male, age 76, midline 51.9
Periaquaductal grey, anterior
nTPM: 58.0
1947 Male, age 18, unknown 61.0
2502 Female, age 75, unknown 61.0
1795 Male, age 51, unknown 52.2
Periaquaductal grey, dorsal
nTPM: 61.0
1840 Male, age 53, unknown 67.6
1831 Male, age 72, unknown 61.2
2464 Female, age 72, unknown 60.7
2850 Male, age 76, both hemispheres 54.6
Periaquaductal grey, lateral
nTPM: 53.7
2053 Male, age 18, unknown 58.2
2140 Male, age 76, both hemispheres 56.4
2272 Male, age 74, both hemispheres 46.4
Pretectal area
nTPM: 63.0
2316 Male, age 76, right hemisphere 72.1
1817 Female, age 42, unknown 70.1
2407 Male, age 75, both hemispheres 69.5
1815 Male, age 53, unknown 69.3
2007 Male, age 72, unknown 66.9
2667 Female, age 75, unknown 62.5
1944 Female, age 72, unknown 62.4
2825 Male, age 18, unknown 60.8
2224 Female, age 72, unknown 55.5
1816 Male, age 51, unknown 54.3
2273 Male, age 74, both hemispheres 49.6
Red nucleus
nTPM: 86.3
2503 Female, age 72, unknown 99.2
1865 Male, age 51, unknown 96.8
1954 Female, age 42, unknown 95.3
1821 Female, age 72, unknown 93.7
2588 Male, age 74, left hemisphere 88.7
1904 Male, age 53, unknown 88.4
2823 Male, age 76, right hemisphere 86.4
2785 Male, age 18, unknown 85.5
2227 Male, age 72, unknown 82.7
2769 Male, age 72, unknown 80.2
2584 Male, age 75, left hemisphere 69.8
2725 Female, age 75, unknown 68.9
Substantia nigra
nTPM: 66.1
2583 Male, age 75, right hemisphere 79.5
2590 Female, age 75, unknown 78.7
2699 Male, age 18, unknown 68.3
1889 Female, age 72, unknown 65.5
2409 Female, age 72, unknown 64.9
1851 Male, age 51, unknown 63.5
2241 Male, age 72, unknown 63.4
1916 Female, age 42, unknown 61.0
1941 Male, age 53, unknown 60.5
2665 Male, age 74, both hemispheres 55.1
Superior colliculus
nTPM: 68.5
1913 Female, age 42, unknown 86.1
1895 Male, age 76, right hemisphere 80.7
1995 Male, age 72, unknown 79.5
1839 Male, age 51, unknown 73.0
2668 Female, age 75, unknown 66.9
2587 Male, age 74, left hemisphere 66.5
2087 Female, age 72, unknown 62.0
2664 Male, age 75, both hemispheres 61.2
1796 Male, age 53, unknown 56.1
2261 Male, age 18, unknown 53.0
Ventral tegmental area
nTPM: 64.2
2410 Female, age 72, unknown 73.3
2223 Female, age 72, unknown 67.2
2021 Male, age 53, unknown 64.1
2218 Male, age 76, both hemispheres 60.9
1915 Female, age 42, unknown 60.2
1942 Male, age 51, unknown 59.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

47.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 47.0
Samples: 139

Max nTPM: 143.8
Min nTPM: 23.9
Std nTPM: 16.5
Median nTPM: 43.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 143.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 93.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 91.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 89.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 81.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 81.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 76.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 75.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 74.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 74.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 73.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 71.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 69.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 69.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 66.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 63.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 61.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 61.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 61.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 60.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 60.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 60.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 60.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 59.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 58.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 58.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 56.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 56.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 56.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 55.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 55.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 54.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 53.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 53.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 52.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 51.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 50.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 50.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 50.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 49.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 49.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 49.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 49.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 48.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 48.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 48.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 48.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 48.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 48.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 47.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 47.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 47.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 46.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 45.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 45.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 45.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 45.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 44.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 44.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 44.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 44.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 44.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 43.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 43.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 43.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 43.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 43.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 43.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 42.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 42.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 42.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 42.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 42.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 42.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 42.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 41.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 41.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 41.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 41.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 41.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 41.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 40.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 40.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 40.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 40.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 39.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 39.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 39.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 39.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 39.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 39.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 39.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 38.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 38.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 38.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 38.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 37.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 37.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 37.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 37.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 36.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 36.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 35.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 35.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 35.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 35.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 34.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 34.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 34.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 33.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 33.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 32.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 32.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 32.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 30.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 30.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 30.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 29.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 28.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 28.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 28.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 27.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 27.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 26.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 26.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 26.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 25.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 25.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 24.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 24.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 23.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 23.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

77.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 77.2
FF:10158-103A5 76 years, female 77.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 97.8
Samples: 4

Max nTPM: 122.8
Min nTPM: 81.9
Sample A Female 88.6
Sample B Female 81.9
Sample C Male 97.8
Sample D Male 122.8
Midbrain
nTPM: 106.6
Samples: 4

Max nTPM: 133.1
Min nTPM: 81.5
Sample A Female 133.1
Sample B Female 117.6
Sample C Male 94.3
Sample D Male 81.5
Periaqueductal gray
nTPM: 92.9
Samples: 3

Max nTPM: 96.9
Min nTPM: 85.4
Sample B Female 96.9
Sample C Male 85.4
Sample D Male 96.3
Superior colliculi
nTPM: 84.1
Samples: 4

Max nTPM: 103.8
Min nTPM: 54.7
Sample A Female 77.2
Sample B Female 54.7
Sample C Male 103.8
Sample D Male 100.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 21.0
Samples: 4

Max nTPM: 22.9
Min nTPM: 17.7
Sample A Male 17.7
Sample B Male 22.9
Sample C Female 22.5
Sample D Female 20.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
70231893 Antisense, RP_050526_02_C01, Mouse strain C57BL/6J (56 days, male) 3.6
73635978 Antisense, RP_051101_03_C11, Mouse strain C57BL/6J (56 days, male) 2.4
71723845 Antisense, RP_050921_01_A06, Mouse strain C57BL/6J (56 days, male) 1.4

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