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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:72.9 nTPM
HPA Brain:91.0 nTPM
GTEx:72.9 nTPM
FANTOM5:127.5 Scaled Tags Per Million
Pig:77.4 nTPM
Mouse:148.0 nTPM
Allen mouse:1.8 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.7
2828 Female, age 72, unknown 87.2
2586 Male, age 75, left hemisphere 73.6
1870 Female, age 42, unknown 61.1
1833 Male, age 53, unknown 58.9
1830 Male, age 51, unknown 58.7
1827 Male, age 72, unknown 57.5
2219 Male, age 76, both hemispheres 51.5
2666 Male, age 74, left hemisphere 47.2
2411 Female, age 72, unknown 41.6
2019 Male, age 18, unknown 39.7
Dorsal raphe nucleus
nTPM: 71.9
2016 Female, age 72, unknown 93.2
2298 Female, age 72, unknown 70.8
1828 Male, age 53, unknown 68.9
2750 Male, age 76, both hemispheres 64.8
2047 Male, age 72, unknown 61.7
Inferior colliculus
nTPM: 63.5
1848 Female, age 42, unknown 83.8
2849 Male, age 72, unknown 63.5
2097 Female, age 72, unknown 56.4
1890 Male, age 53, unknown 50.5
Median raphe nucleus
nTPM: 91.0
2220 Male, age 76, midline 91.0
Periaquaductal grey, anterior
nTPM: 65.5
1795 Male, age 51, unknown 75.5
1947 Male, age 18, unknown 69.0
2502 Female, age 75, unknown 52.1
Periaquaductal grey, dorsal
nTPM: 66.0
1831 Male, age 72, unknown 82.3
1840 Male, age 53, unknown 74.6
2850 Male, age 76, both hemispheres 60.2
2464 Female, age 72, unknown 47.0
Periaquaductal grey, lateral
nTPM: 89.7
2272 Male, age 74, both hemispheres 121.1
2053 Male, age 18, unknown 84.5
2140 Male, age 76, both hemispheres 63.7
Pretectal area
nTPM: 71.6
2273 Male, age 74, both hemispheres 124.2
2407 Male, age 75, both hemispheres 88.2
2667 Female, age 75, unknown 81.7
2224 Female, age 72, unknown 80.7
2825 Male, age 18, unknown 80.4
1944 Female, age 72, unknown 65.5
1817 Female, age 42, unknown 63.0
1815 Male, age 53, unknown 61.8
2316 Male, age 76, right hemisphere 60.8
1816 Male, age 51, unknown 43.9
2007 Male, age 72, unknown 37.5
Red nucleus
nTPM: 67.5
2725 Female, age 75, unknown 86.4
1954 Female, age 42, unknown 81.4
1865 Male, age 51, unknown 80.9
2823 Male, age 76, right hemisphere 76.2
2227 Male, age 72, unknown 76.0
2769 Male, age 72, unknown 75.5
2503 Female, age 72, unknown 74.6
1904 Male, age 53, unknown 63.8
1821 Female, age 72, unknown 62.5
2785 Male, age 18, unknown 50.7
2584 Male, age 75, left hemisphere 42.7
2588 Male, age 74, left hemisphere 38.9
Substantia nigra
nTPM: 64.8
2699 Male, age 18, unknown 116.4
2583 Male, age 75, right hemisphere 70.7
1889 Female, age 72, unknown 69.3
1916 Female, age 42, unknown 68.3
1851 Male, age 51, unknown 68.2
2590 Female, age 75, unknown 65.6
1941 Male, age 53, unknown 55.7
2241 Male, age 72, unknown 48.0
2665 Male, age 74, both hemispheres 45.6
2409 Female, age 72, unknown 39.9
Superior colliculus
nTPM: 71.4
1995 Male, age 72, unknown 105.7
1796 Male, age 53, unknown 92.2
1913 Female, age 42, unknown 85.0
2587 Male, age 74, left hemisphere 76.4
2664 Male, age 75, both hemispheres 70.1
2087 Female, age 72, unknown 63.0
1839 Male, age 51, unknown 60.4
2261 Male, age 18, unknown 55.2
1895 Male, age 76, right hemisphere 54.2
2668 Female, age 75, unknown 51.7
Ventral tegmental area
nTPM: 69.0
2223 Female, age 72, unknown 79.2
1942 Male, age 51, unknown 74.1
1915 Female, age 42, unknown 71.8
2021 Male, age 53, unknown 68.9
2218 Male, age 76, both hemispheres 64.6
2410 Female, age 72, unknown 55.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.9
Samples: 139

Max nTPM: 180.2
Min nTPM: 18.8
Std nTPM: 28.4
Median nTPM: 71.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 180.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 176.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 137.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 124.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 123.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 123.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 122.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 120.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 117.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 114.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 113.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 111.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 110.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 109.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 108.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 108.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 106.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 105.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 104.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 102.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 99.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 99.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 99.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 99.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 98.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 97.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 97.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 96.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 96.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 95.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 94.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 93.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 92.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 92.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 91.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 90.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 89.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 89.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 87.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 87.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 86.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 86.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 85.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 84.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 84.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 83.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 81.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 81.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 81.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 80.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 79.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 78.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 78.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 78.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 77.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 75.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 75.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 75.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 75.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 74.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 74.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 73.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 73.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 73.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 72.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 72.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 72.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 71.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 71.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 70.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 68.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 68.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 68.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 67.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 66.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 66.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 65.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 64.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 64.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 63.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 63.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 63.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 63.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 63.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 61.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 61.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 61.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 61.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 60.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 60.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 60.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 59.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 58.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 56.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 54.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 53.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 53.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 52.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 51.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 50.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 50.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 49.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 49.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 47.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 47.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 47.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 46.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 46.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 45.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 45.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 45.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 45.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 44.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 44.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 43.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 42.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 42.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 41.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 40.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 40.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 39.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 37.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 36.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 33.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 33.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 32.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 31.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 30.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 29.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 25.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 23.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 18.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

127.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 127.5
FF:10158-103A5 76 years, female 127.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 77.4
Samples: 4

Max nTPM: 96.6
Min nTPM: 69.7
Sample A Female 69.7
Sample B Female 72.5
Sample C Male 70.9
Sample D Male 96.6
Midbrain
nTPM: 75.6
Samples: 4

Max nTPM: 123.5
Min nTPM: 29.0
Sample A Female 123.5
Sample B Female 47.4
Sample C Male 102.5
Sample D Male 29.0
Periaqueductal gray
nTPM: 57.8
Samples: 3

Max nTPM: 68.8
Min nTPM: 45.6
Sample B Female 45.6
Sample C Male 68.8
Sample D Male 59.1
Superior colliculi
nTPM: 76.9
Samples: 4

Max nTPM: 109.8
Min nTPM: 60.0
Sample A Female 60.0
Sample B Female 66.6
Sample C Male 109.8
Sample D Male 71.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

148.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 148.0
Samples: 4

Max nTPM: 156.5
Min nTPM: 141.4
Sample A Male 156.5
Sample B Male 141.4
Sample C Female 149.1
Sample D Female 145.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.8
71836806 Antisense, RP_051017_02_A11, Mouse strain C57BL/6J (56 days, male) 2.4
413825 Antisense, RP_040809_01_G11, Mouse strain C57BL/6J (56 days, male) 1.2

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