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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:64.9 nTPM
HPA Brain:135.6 nTPM
GTEx:64.9 nTPM
FANTOM5:97.1 Scaled Tags Per Million
Pig:301.0 nTPM
Mouse:225.5 nTPM
Allen mouse:8.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

135.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 108.2
2219 Male, age 76, both hemispheres 146.5
2411 Female, age 72, unknown 121.6
2586 Male, age 75, left hemisphere 120.0
2666 Male, age 74, left hemisphere 109.5
1827 Male, age 72, unknown 108.5
2019 Male, age 18, unknown 105.9
1870 Female, age 42, unknown 98.1
1833 Male, age 53, unknown 95.4
1830 Male, age 51, unknown 89.0
2828 Female, age 72, unknown 87.7
Dorsal raphe nucleus
nTPM: 110.7
2298 Female, age 72, unknown 121.9
1828 Male, age 53, unknown 121.7
2047 Male, age 72, unknown 118.3
2750 Male, age 76, both hemispheres 110.6
2016 Female, age 72, unknown 80.8
Inferior colliculus
nTPM: 96.4
2097 Female, age 72, unknown 109.9
1890 Male, age 53, unknown 96.8
1848 Female, age 42, unknown 95.2
2849 Male, age 72, unknown 83.6
Median raphe nucleus
nTPM: 114.1
2220 Male, age 76, midline 114.1
Periaquaductal grey, anterior
nTPM: 106.9
2502 Female, age 75, unknown 113.2
1947 Male, age 18, unknown 111.0
1795 Male, age 51, unknown 96.4
Periaquaductal grey, dorsal
nTPM: 83.0
1840 Male, age 53, unknown 94.9
2464 Female, age 72, unknown 85.9
1831 Male, age 72, unknown 80.1
2850 Male, age 76, both hemispheres 71.2
Periaquaductal grey, lateral
nTPM: 73.8
2053 Male, age 18, unknown 77.5
2272 Male, age 74, both hemispheres 73.1
2140 Male, age 76, both hemispheres 70.9
Pretectal area
nTPM: 99.7
1816 Male, age 51, unknown 125.0
2007 Male, age 72, unknown 123.7
1817 Female, age 42, unknown 115.4
1944 Female, age 72, unknown 115.0
1815 Male, age 53, unknown 105.7
2667 Female, age 75, unknown 93.5
2825 Male, age 18, unknown 92.3
2224 Female, age 72, unknown 91.9
2407 Male, age 75, both hemispheres 87.7
2316 Male, age 76, right hemisphere 78.1
2273 Male, age 74, both hemispheres 68.8
Red nucleus
nTPM: 102.1
1821 Female, age 72, unknown 134.2
2584 Male, age 75, left hemisphere 115.6
1954 Female, age 42, unknown 102.8
2588 Male, age 74, left hemisphere 102.5
2227 Male, age 72, unknown 101.9
2725 Female, age 75, unknown 101.9
1904 Male, age 53, unknown 98.9
2769 Male, age 72, unknown 97.8
2785 Male, age 18, unknown 96.5
1865 Male, age 51, unknown 96.3
2503 Female, age 72, unknown 93.6
2823 Male, age 76, right hemisphere 82.6
Substantia nigra
nTPM: 135.6
1916 Female, age 42, unknown 199.6
2241 Male, age 72, unknown 159.4
1851 Male, age 51, unknown 155.0
1941 Male, age 53, unknown 134.5
2409 Female, age 72, unknown 131.4
1889 Female, age 72, unknown 122.9
2699 Male, age 18, unknown 121.0
2583 Male, age 75, right hemisphere 117.5
2665 Male, age 74, both hemispheres 109.7
2590 Female, age 75, unknown 105.2
Superior colliculus
nTPM: 92.9
2668 Female, age 75, unknown 114.6
2087 Female, age 72, unknown 106.5
2261 Male, age 18, unknown 104.6
1796 Male, age 53, unknown 94.3
2664 Male, age 75, both hemispheres 94.0
1839 Male, age 51, unknown 93.1
1895 Male, age 76, right hemisphere 88.7
2587 Male, age 74, left hemisphere 87.5
1913 Female, age 42, unknown 78.0
1995 Male, age 72, unknown 67.7
Ventral tegmental area
nTPM: 120.8
2410 Female, age 72, unknown 147.4
1915 Female, age 42, unknown 138.8
2218 Male, age 76, both hemispheres 128.6
1942 Male, age 51, unknown 111.3
2223 Female, age 72, unknown 103.3
2021 Male, age 53, unknown 95.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 64.9
Samples: 139

Max nTPM: 151.3
Min nTPM: 31.8
Std nTPM: 22.9
Median nTPM: 56.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 151.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 146.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 132.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 131.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 120.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 115.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 111.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 109.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 107.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 99.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 99.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 98.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 95.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 95.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 94.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 94.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 92.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 91.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 90.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 90.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 89.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 89.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 89.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 86.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 86.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 86.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 84.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 82.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 80.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 79.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 79.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 76.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 75.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 75.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 75.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 73.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 72.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 72.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 71.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 71.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 71.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 71.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 70.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 68.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 68.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 68.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 68.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 66.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 66.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 66.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 66.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 66.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 66.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 63.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 63.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 63.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 62.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 60.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 59.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 59.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 58.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 58.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 58.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 58.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 58.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 56.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 56.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 56.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 55.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 55.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 55.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 55.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 55.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 55.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 54.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 54.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 54.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 54.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 53.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 53.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 53.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 53.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 53.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 53.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 53.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 52.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 52.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 52.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 52.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 52.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 51.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 51.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 51.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 51.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 51.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 51.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 50.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 49.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 49.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 49.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 48.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 48.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 48.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 47.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 47.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 46.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 46.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 46.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 46.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 46.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 45.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 45.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 45.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 44.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 44.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 44.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 44.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 44.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 44.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 44.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 43.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 43.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 42.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 42.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 42.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 42.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 40.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 40.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 40.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 37.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 36.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 34.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 31.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

97.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 97.1
FF:10158-103A5 76 years, female 97.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

301.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 241.0
Samples: 4

Max nTPM: 324.0
Min nTPM: 178.3
Sample A Female 324.0
Sample B Female 191.5
Sample C Male 270.1
Sample D Male 178.3
Midbrain
nTPM: 289.0
Samples: 4

Max nTPM: 336.8
Min nTPM: 260.1
Sample A Female 297.9
Sample B Female 260.1
Sample C Male 336.8
Sample D Male 261.2
Periaqueductal gray
nTPM: 218.1
Samples: 3

Max nTPM: 241.3
Min nTPM: 180.3
Sample B Female 232.6
Sample C Male 241.3
Sample D Male 180.3
Superior colliculi
nTPM: 301.0
Samples: 4

Max nTPM: 347.6
Min nTPM: 236.8
Sample A Female 347.6
Sample B Female 236.8
Sample C Male 337.9
Sample D Male 281.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

225.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 225.5
Samples: 4

Max nTPM: 228.9
Min nTPM: 221.5
Sample A Male 223.2
Sample B Male 228.3
Sample C Female 228.9
Sample D Female 221.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.6
69028402 Antisense, RP_050316_01_C04, Mouse strain C57BL/6J (56 days, male) 8.6

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