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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
97.3
nTPM
HPA:
62.4
nTPM
GTEx:
97.3
nTPM
FANTOM5:
96.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA039505
Cholangiocytes
High
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
62.4
Female, age 60
Liver sample 21 nTPM: 72.9
Male, age 54
Liver sample 23 nTPM: 54.3
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 74
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 40.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 48.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 52.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 51.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 84.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 72.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 72.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
97.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 97.3
Samples: 226
Max nTPM: 194.9
Min nTPM: 40.1
Std nTPM: 24.1
Median nTPM: 95.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
194.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
181.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
171.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
166.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
164.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
154.7
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
146.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
144.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
144.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
141.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
141.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
139.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
138.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
137.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
135.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
134.9
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
134.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
133.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
129.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
128.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
126.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
126.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
124.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
122.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
122.1
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
122.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
121.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
121.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
121.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
120.2
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
119.8
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
119.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
119.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
119.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
118.3
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
118.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
118.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
117.9
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
117.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
117.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
116.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
116.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
115.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
115.7
GTEX-X261-1726-SM-4PQYT
50-59 years, male
115.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
115.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
114.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
114.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
114.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
113.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
112.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
112.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
112.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
112.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
112.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
111.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
111.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
111.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
111.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
110.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
110.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
109.9
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
109.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
109.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
109.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
108.5
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
108.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
108.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
107.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
107.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
107.0
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
106.6
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
106.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
105.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
105.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
105.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
105.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
105.3
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
105.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
104.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
104.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
104.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
103.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
103.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
103.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
102.1
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
101.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
101.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
101.6
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
101.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
101.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
101.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
100.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
100.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
99.8
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
99.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
99.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
99.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
99.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
99.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
99.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
99.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
99.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
98.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
98.6
GTEX-13113-1326-SM-5GCOI
60-69 years, female
98.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
98.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
97.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
96.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
96.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
96.1
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
96.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
95.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
95.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
94.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
94.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
94.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
94.3
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
94.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
94.3
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
94.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
94.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
94.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
93.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
93.7
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
92.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
92.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
92.7
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
92.7
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
92.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
91.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
91.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
90.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
90.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
90.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
90.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
89.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
89.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
89.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
88.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
88.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
87.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
86.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
85.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
85.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
85.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
85.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
84.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
84.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
84.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
84.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
83.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
83.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
83.1
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
83.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
82.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
82.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
82.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
82.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
81.9
GTEX-1B933-1226-SM-731DW
50-59 years, female
81.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
81.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
81.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
81.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
81.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
81.5
GTEX-17F96-1226-SM-79OK2
70-79 years, male
81.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
81.4
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
81.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
81.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
81.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
80.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
80.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
80.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
79.7
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
79.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
79.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
78.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
78.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
78.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
78.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
78.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
78.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
77.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
77.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
77.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
76.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
76.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
76.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
76.0
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
75.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
75.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
75.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
75.0
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
74.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
74.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
74.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
73.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
73.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
73.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
72.2
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
72.2
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
72.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
71.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
71.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
70.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
70.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
70.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
68.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
66.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
66.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
64.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
64.4
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
64.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
61.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
58.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
56.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
56.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
56.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
56.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
55.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
51.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
50.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
48.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
43.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
40.1
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
