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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:38.0 nTPM
HPA Brain:44.6 nTPM
GTEx:38.0 nTPM
FANTOM5:35.8 Scaled Tags Per Million
Pig:23.9 nTPM
Mouse:18.3 nTPM
Allen mouse:1.9 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.5
2666 Male, age 74, left hemisphere 57.1
2586 Male, age 75, left hemisphere 56.4
2019 Male, age 18, unknown 50.0
2411 Female, age 72, unknown 49.8
1870 Female, age 42, unknown 42.4
1830 Male, age 51, unknown 41.9
2828 Female, age 72, unknown 37.4
1833 Male, age 53, unknown 37.2
1827 Male, age 72, unknown 35.6
2219 Male, age 76, both hemispheres 27.5
Dorsal raphe nucleus
nTPM: 39.5
2750 Male, age 76, both hemispheres 46.4
2047 Male, age 72, unknown 42.4
2298 Female, age 72, unknown 39.9
1828 Male, age 53, unknown 38.2
2016 Female, age 72, unknown 30.4
Inferior colliculus
nTPM: 32.7
1890 Male, age 53, unknown 35.4
1848 Female, age 42, unknown 33.2
2097 Female, age 72, unknown 31.2
2849 Male, age 72, unknown 30.8
Median raphe nucleus
nTPM: 35.3
2220 Male, age 76, midline 35.3
Periaquaductal grey, anterior
nTPM: 36.6
1947 Male, age 18, unknown 38.5
2502 Female, age 75, unknown 36.3
1795 Male, age 51, unknown 35.0
Periaquaductal grey, dorsal
nTPM: 31.1
1840 Male, age 53, unknown 33.3
2464 Female, age 72, unknown 33.0
1831 Male, age 72, unknown 31.3
2850 Male, age 76, both hemispheres 26.7
Periaquaductal grey, lateral
nTPM: 28.2
2053 Male, age 18, unknown 28.6
2272 Male, age 74, both hemispheres 28.2
2140 Male, age 76, both hemispheres 27.7
Pretectal area
nTPM: 34.5
1817 Female, age 42, unknown 44.5
2007 Male, age 72, unknown 43.3
1816 Male, age 51, unknown 37.4
2825 Male, age 18, unknown 37.1
2224 Female, age 72, unknown 35.1
1815 Male, age 53, unknown 32.7
2407 Male, age 75, both hemispheres 31.8
2667 Female, age 75, unknown 31.4
1944 Female, age 72, unknown 29.1
2316 Male, age 76, right hemisphere 29.0
2273 Male, age 74, both hemispheres 28.1
Red nucleus
nTPM: 44.6
2588 Male, age 74, left hemisphere 54.7
2584 Male, age 75, left hemisphere 49.8
2227 Male, age 72, unknown 47.1
2769 Male, age 72, unknown 46.8
1865 Male, age 51, unknown 46.7
1821 Female, age 72, unknown 46.4
1904 Male, age 53, unknown 46.1
2785 Male, age 18, unknown 44.1
1954 Female, age 42, unknown 42.2
2823 Male, age 76, right hemisphere 41.5
2725 Female, age 75, unknown 35.6
2503 Female, age 72, unknown 33.9
Substantia nigra
nTPM: 38.5
2583 Male, age 75, right hemisphere 47.7
2665 Male, age 74, both hemispheres 43.9
1916 Female, age 42, unknown 42.1
1941 Male, age 53, unknown 42.0
2590 Female, age 75, unknown 39.7
1889 Female, age 72, unknown 38.7
1851 Male, age 51, unknown 38.5
2241 Male, age 72, unknown 34.2
2409 Female, age 72, unknown 29.6
2699 Male, age 18, unknown 28.4
Superior colliculus
nTPM: 33.5
2668 Female, age 75, unknown 43.4
1839 Male, age 51, unknown 35.5
2587 Male, age 74, left hemisphere 35.2
2664 Male, age 75, both hemispheres 32.9
2261 Male, age 18, unknown 32.6
2087 Female, age 72, unknown 31.7
1796 Male, age 53, unknown 31.4
1895 Male, age 76, right hemisphere 31.2
1913 Female, age 42, unknown 31.0
1995 Male, age 72, unknown 29.9
Ventral tegmental area
nTPM: 42.0
2223 Female, age 72, unknown 64.5
2410 Female, age 72, unknown 40.8
2021 Male, age 53, unknown 39.6
1915 Female, age 42, unknown 37.5
1942 Male, age 51, unknown 34.9
2218 Male, age 76, both hemispheres 34.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

38.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 38.0
Samples: 139

Max nTPM: 86.1
Min nTPM: 19.3
Std nTPM: 11.3
Median nTPM: 35.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 86.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 77.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 64.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 62.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 62.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 60.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 60.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 60.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 59.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 55.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 53.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 53.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 52.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 52.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 51.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 51.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 51.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 51.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 50.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 50.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 50.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 49.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 49.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 47.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 47.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 47.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 46.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 45.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 45.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 45.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 44.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 44.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 44.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 44.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 43.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 43.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 43.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 43.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 42.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 42.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 41.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 41.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 41.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 40.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 40.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 40.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 39.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 39.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 39.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 38.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 38.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 38.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 37.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 37.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 37.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 37.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 37.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 37.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 36.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 36.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 36.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 36.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 36.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 36.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 35.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 35.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 35.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 34.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 34.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 34.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 34.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 34.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 34.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 34.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 34.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 33.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 33.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 33.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 33.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 32.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 32.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 32.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 32.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 32.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 32.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 31.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 31.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 31.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 31.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 31.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 31.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 31.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 30.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 30.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 30.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 30.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 30.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 30.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 29.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 29.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 29.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 29.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 29.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 28.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 28.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 28.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 28.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 27.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 27.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 27.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 27.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 27.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 27.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 27.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 26.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 26.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 26.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 25.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 25.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 24.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 23.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 23.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 23.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 22.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 22.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 21.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 20.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 20.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 19.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 19.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

35.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 35.8
FF:10158-103A5 76 years, female 35.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 22.5
Samples: 4

Max nTPM: 24.4
Min nTPM: 20.7
Sample A Female 24.2
Sample B Female 24.4
Sample C Male 20.7
Sample D Male 20.7
Midbrain
nTPM: 20.7
Samples: 4

Max nTPM: 28.9
Min nTPM: 17.3
Sample A Female 28.9
Sample B Female 17.3
Sample C Male 17.9
Sample D Male 18.7
Periaqueductal gray
nTPM: 14.6
Samples: 3

Max nTPM: 15.6
Min nTPM: 13.3
Sample B Female 14.8
Sample C Male 15.6
Sample D Male 13.3
Superior colliculi
nTPM: 24.0
Samples: 4

Max nTPM: 28.6
Min nTPM: 18.3
Sample A Female 26.7
Sample B Female 28.6
Sample C Male 22.2
Sample D Male 18.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

18.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 18.3
Samples: 4

Max nTPM: 19.7
Min nTPM: 17.6
Sample A Male 17.6
Sample B Male 17.6
Sample C Female 19.7
Sample D Female 18.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.9
69817793 Antisense, RP_050510_03_G08, Mouse strain C57BL/6J (56 days, male) 1.9

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