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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:49.1 nTPM
HPA Brain:230.5 nTPM
GTEx:49.1 nTPM
FANTOM5:80.3 Scaled Tags Per Million
Pig:125.3 nTPM
Mouse:32.8 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

230.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 97.5
2828 Female, age 72, unknown 179.5
1827 Male, age 72, unknown 165.9
2019 Male, age 18, unknown 102.3
2586 Male, age 75, left hemisphere 97.8
1833 Male, age 53, unknown 88.3
1870 Female, age 42, unknown 78.9
1830 Male, age 51, unknown 73.8
2411 Female, age 72, unknown 66.4
2666 Male, age 74, left hemisphere 65.9
2219 Male, age 76, both hemispheres 56.1
Dorsal raphe nucleus
nTPM: 110.9
2298 Female, age 72, unknown 152.9
2016 Female, age 72, unknown 148.4
1828 Male, age 53, unknown 112.7
2047 Male, age 72, unknown 74.5
2750 Male, age 76, both hemispheres 65.9
Inferior colliculus
nTPM: 96.0
1848 Female, age 42, unknown 127.7
2097 Female, age 72, unknown 89.0
2849 Male, age 72, unknown 85.3
1890 Male, age 53, unknown 81.9
Median raphe nucleus
nTPM: 72.8
2220 Male, age 76, midline 72.8
Periaquaductal grey, anterior
nTPM: 144.0
1795 Male, age 51, unknown 196.2
2502 Female, age 75, unknown 119.3
1947 Male, age 18, unknown 116.5
Periaquaductal grey, dorsal
nTPM: 157.4
2850 Male, age 76, both hemispheres 202.6
1831 Male, age 72, unknown 180.7
1840 Male, age 53, unknown 139.5
2464 Female, age 72, unknown 106.9
Periaquaductal grey, lateral
nTPM: 230.5
2272 Male, age 74, both hemispheres 346.0
2140 Male, age 76, both hemispheres 173.2
2053 Male, age 18, unknown 172.4
Pretectal area
nTPM: 203.5
2273 Male, age 74, both hemispheres 533.8
1816 Male, age 51, unknown 233.2
1944 Female, age 72, unknown 218.0
1815 Male, age 53, unknown 183.5
2007 Male, age 72, unknown 171.9
1817 Female, age 42, unknown 170.1
2667 Female, age 75, unknown 161.7
2224 Female, age 72, unknown 159.5
2407 Male, age 75, both hemispheres 153.8
2316 Male, age 76, right hemisphere 140.1
2825 Male, age 18, unknown 113.4
Red nucleus
nTPM: 87.2
2725 Female, age 75, unknown 135.3
2785 Male, age 18, unknown 119.3
2823 Male, age 76, right hemisphere 92.9
2503 Female, age 72, unknown 92.7
1865 Male, age 51, unknown 91.4
1904 Male, age 53, unknown 89.2
1954 Female, age 42, unknown 84.4
2769 Male, age 72, unknown 77.4
1821 Female, age 72, unknown 77.1
2227 Male, age 72, unknown 74.4
2588 Male, age 74, left hemisphere 64.7
2584 Male, age 75, left hemisphere 47.2
Substantia nigra
nTPM: 92.2
1889 Female, age 72, unknown 145.7
2590 Female, age 75, unknown 108.0
2409 Female, age 72, unknown 97.4
1851 Male, age 51, unknown 96.3
2699 Male, age 18, unknown 95.2
1916 Female, age 42, unknown 86.8
2665 Male, age 74, both hemispheres 79.8
1941 Male, age 53, unknown 77.0
2583 Male, age 75, right hemisphere 68.9
2241 Male, age 72, unknown 66.6
Superior colliculus
nTPM: 151.7
2261 Male, age 18, unknown 215.6
2087 Female, age 72, unknown 194.9
1995 Male, age 72, unknown 189.1
2587 Male, age 74, left hemisphere 172.7
1796 Male, age 53, unknown 161.7
1913 Female, age 42, unknown 154.3
2664 Male, age 75, both hemispheres 121.6
1895 Male, age 76, right hemisphere 108.6
2668 Female, age 75, unknown 102.5
1839 Male, age 51, unknown 95.7
Ventral tegmental area
nTPM: 83.3
2021 Male, age 53, unknown 100.2
2410 Female, age 72, unknown 98.3
1915 Female, age 42, unknown 84.9
2218 Male, age 76, both hemispheres 79.9
1942 Male, age 51, unknown 75.3
2223 Female, age 72, unknown 61.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 49.1
Samples: 139

Max nTPM: 217.3
Min nTPM: 12.0
Std nTPM: 31.7
Median nTPM: 41.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 217.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 160.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 151.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 150.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 128.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 124.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 122.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 116.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 108.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 97.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 96.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 95.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 88.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 84.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 83.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 79.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 78.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 77.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 75.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 74.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 73.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 73.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 71.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 70.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 70.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 70.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 69.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 64.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 61.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 60.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 60.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 57.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 56.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 55.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 54.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 53.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 53.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 51.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 51.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 51.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 51.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 51.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 50.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 50.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 50.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 48.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 48.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 48.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 48.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 48.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 47.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 47.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 47.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 47.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 47.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 47.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 46.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 45.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 44.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 44.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 43.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 42.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 41.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 41.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 41.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 40.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 40.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 39.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 38.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 38.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 37.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 37.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 35.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 35.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 35.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 34.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 34.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 34.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 34.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 34.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 33.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 33.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 33.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 33.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 33.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 32.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 32.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 32.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 32.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 32.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 31.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 31.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 31.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 29.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 28.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 28.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 27.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 27.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 26.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 26.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 25.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 25.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 25.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 25.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 25.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 25.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 25.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 25.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 24.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 24.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 24.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 24.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 24.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 23.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 22.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 21.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 21.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 21.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 21.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 21.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 20.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 20.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 19.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 18.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 17.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 17.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 17.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 12.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 12.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 12.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

80.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 80.3
FF:10158-103A5 76 years, female 80.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

125.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 63.8
Samples: 4

Max nTPM: 77.9
Min nTPM: 49.4
Sample A Female 65.4
Sample B Female 77.9
Sample C Male 49.4
Sample D Male 62.6
Midbrain
nTPM: 105.6
Samples: 4

Max nTPM: 215.3
Min nTPM: 34.4
Sample A Female 132.9
Sample B Female 39.9
Sample C Male 215.3
Sample D Male 34.4
Periaqueductal gray
nTPM: 88.4
Samples: 3

Max nTPM: 101.3
Min nTPM: 67.8
Sample B Female 67.8
Sample C Male 101.3
Sample D Male 96.1
Superior colliculi
nTPM: 125.3
Samples: 4

Max nTPM: 215.5
Min nTPM: 65.5
Sample A Female 65.5
Sample B Female 215.5
Sample C Male 136.6
Sample D Male 83.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 32.8
Samples: 4

Max nTPM: 34.7
Min nTPM: 30.8
Sample A Male 33.8
Sample B Male 34.7
Sample C Female 31.8
Sample D Female 30.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
69015727 Antisense, RP_050315_01_F01, Mouse strain C57BL/6J (56 days, male) 1.7
72077452 Antisense, RP_051017_03_A06, Mouse strain C57BL/6J (56 days, male) 1.5

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