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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:20.4 nTPM
HPA Brain:41.7 nTPM
GTEx:20.4 nTPM
FANTOM5:31.1 Scaled Tags Per Million
Pig:30.6 nTPM
Mouse:11.1 nTPM
Allen mouse:4.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 26.2
2019 Male, age 18, unknown 33.9
2219 Male, age 76, both hemispheres 32.8
2666 Male, age 74, left hemisphere 31.5
2586 Male, age 75, left hemisphere 31.3
2828 Female, age 72, unknown 27.3
1827 Male, age 72, unknown 25.6
1870 Female, age 42, unknown 20.8
1833 Male, age 53, unknown 19.9
1830 Male, age 51, unknown 19.7
2411 Female, age 72, unknown 19.0
Dorsal raphe nucleus
nTPM: 26.4
1828 Male, age 53, unknown 39.2
2047 Male, age 72, unknown 36.1
2750 Male, age 76, both hemispheres 19.6
2298 Female, age 72, unknown 18.5
2016 Female, age 72, unknown 18.3
Inferior colliculus
nTPM: 34.6
1890 Male, age 53, unknown 43.5
2097 Female, age 72, unknown 40.1
1848 Female, age 42, unknown 30.0
2849 Male, age 72, unknown 25.0
Median raphe nucleus
nTPM: 19.8
2220 Male, age 76, midline 19.8
Periaquaductal grey, anterior
nTPM: 41.7
1795 Male, age 51, unknown 53.2
1947 Male, age 18, unknown 44.4
2502 Female, age 75, unknown 27.4
Periaquaductal grey, dorsal
nTPM: 23.5
2850 Male, age 76, both hemispheres 28.1
2464 Female, age 72, unknown 23.9
1840 Male, age 53, unknown 21.5
1831 Male, age 72, unknown 20.7
Periaquaductal grey, lateral
nTPM: 27.5
2140 Male, age 76, both hemispheres 30.0
2272 Male, age 74, both hemispheres 26.9
2053 Male, age 18, unknown 25.5
Pretectal area
nTPM: 36.5
1944 Female, age 72, unknown 58.7
1816 Male, age 51, unknown 57.1
2007 Male, age 72, unknown 46.2
2667 Female, age 75, unknown 40.1
2316 Male, age 76, right hemisphere 38.2
1817 Female, age 42, unknown 36.6
2407 Male, age 75, both hemispheres 28.4
1815 Male, age 53, unknown 27.0
2224 Female, age 72, unknown 25.1
2825 Male, age 18, unknown 22.1
2273 Male, age 74, both hemispheres 21.8
Red nucleus
nTPM: 21.2
2785 Male, age 18, unknown 41.3
2503 Female, age 72, unknown 28.8
2584 Male, age 75, left hemisphere 23.6
2227 Male, age 72, unknown 21.9
2588 Male, age 74, left hemisphere 21.8
2769 Male, age 72, unknown 21.8
1865 Male, age 51, unknown 18.6
1904 Male, age 53, unknown 17.7
2823 Male, age 76, right hemisphere 17.3
1954 Female, age 42, unknown 17.2
1821 Female, age 72, unknown 15.7
2725 Female, age 75, unknown 9.1
Substantia nigra
nTPM: 23.2
2665 Male, age 74, both hemispheres 34.6
1889 Female, age 72, unknown 31.3
2583 Male, age 75, right hemisphere 30.2
2590 Female, age 75, unknown 28.8
1941 Male, age 53, unknown 28.2
1916 Female, age 42, unknown 19.0
2241 Male, age 72, unknown 17.8
1851 Male, age 51, unknown 17.1
2409 Female, age 72, unknown 12.3
2699 Male, age 18, unknown 12.3
Superior colliculus
nTPM: 30.3
2668 Female, age 75, unknown 58.8
2087 Female, age 72, unknown 40.8
2664 Male, age 75, both hemispheres 31.5
1913 Female, age 42, unknown 28.0
2261 Male, age 18, unknown 28.0
1839 Male, age 51, unknown 24.0
1796 Male, age 53, unknown 23.5
1995 Male, age 72, unknown 23.2
2587 Male, age 74, left hemisphere 23.2
1895 Male, age 76, right hemisphere 22.2
Ventral tegmental area
nTPM: 20.1
2218 Male, age 76, both hemispheres 23.8
2223 Female, age 72, unknown 22.3
1942 Male, age 51, unknown 19.3
2410 Female, age 72, unknown 18.9
2021 Male, age 53, unknown 18.8
1915 Female, age 42, unknown 17.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 20.4
Samples: 139

Max nTPM: 44.4
Min nTPM: 2.7
Std nTPM: 7.5
Median nTPM: 20.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 44.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 42.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 40.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 39.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 37.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 37.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 35.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 34.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 33.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 32.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 30.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 30.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 30.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 30.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 29.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 29.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 28.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 28.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 27.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 27.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 27.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 27.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 27.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 27.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 26.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 26.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 25.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 25.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 25.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 24.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 24.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 24.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 24.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 23.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 23.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 23.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 23.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 23.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 23.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 23.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 22.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 22.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 22.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 22.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 22.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 22.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 22.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 22.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 22.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 21.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 21.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 21.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 21.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 21.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 21.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 21.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 21.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 21.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 21.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 21.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 21.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 20.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 20.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 20.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 20.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 20.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 20.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 20.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 19.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 19.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 19.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 19.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 18.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 18.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 18.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 18.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 18.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 18.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 18.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 17.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 17.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 17.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 17.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 17.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 17.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 17.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 17.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 17.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 17.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 16.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 16.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 16.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 16.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 16.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 16.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 16.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 15.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 15.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 15.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 15.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 15.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 14.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 14.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 14.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 14.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 14.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 14.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 13.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 13.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 13.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 13.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 13.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 13.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 13.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 13.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 12.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 12.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 12.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 11.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 11.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 11.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 11.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 10.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 10.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 10.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 10.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 10.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 9.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 8.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 7.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 6.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 4.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.1
FF:10158-103A5 76 years, female 31.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 12.7
Samples: 4

Max nTPM: 17.0
Min nTPM: 9.0
Sample A Female 17.0
Sample B Female 9.0
Sample C Male 11.4
Sample D Male 13.4
Midbrain
nTPM: 30.6
Samples: 4

Max nTPM: 51.9
Min nTPM: 15.0
Sample A Female 23.0
Sample B Female 15.0
Sample C Male 51.9
Sample D Male 32.4
Periaqueductal gray
nTPM: 13.4
Samples: 3

Max nTPM: 15.8
Min nTPM: 10.9
Sample B Female 15.8
Sample C Male 13.4
Sample D Male 10.9
Superior colliculi
nTPM: 26.0
Samples: 4

Max nTPM: 33.8
Min nTPM: 20.0
Sample A Female 33.8
Sample B Female 20.0
Sample C Male 22.8
Sample D Male 27.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 11.1
Samples: 4

Max nTPM: 12.9
Min nTPM: 9.9
Sample A Male 12.9
Sample B Male 10.8
Sample C Female 10.6
Sample D Female 9.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.2
71656884 Antisense, RP_050927_04_E03, Mouse strain C57BL/6J (56 days, male) 4.2
74357578 Antisense, RP_050927_04_E03, Mouse strain C57BL/6J (56 days, male) 3.0

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