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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:55.4 nTPM
HPA Brain:65.9 nTPM
GTEx:55.4 nTPM
FANTOM5:31.5 Scaled Tags Per Million
Pig:21.6 nTPM
Mouse:60.6 nTPM
Allen mouse:2.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

65.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 56.8
2586 Male, age 75, left hemisphere 79.3
2019 Male, age 18, unknown 60.9
2411 Female, age 72, unknown 59.1
2666 Male, age 74, left hemisphere 56.0
1827 Male, age 72, unknown 55.9
1833 Male, age 53, unknown 54.6
2828 Female, age 72, unknown 53.8
2219 Male, age 76, both hemispheres 50.2
1830 Male, age 51, unknown 49.6
1870 Female, age 42, unknown 48.4
Dorsal raphe nucleus
nTPM: 57.1
1828 Male, age 53, unknown 64.2
2047 Male, age 72, unknown 61.0
2016 Female, age 72, unknown 56.7
2298 Female, age 72, unknown 51.9
2750 Male, age 76, both hemispheres 51.4
Inferior colliculus
nTPM: 54.8
1890 Male, age 53, unknown 59.9
2097 Female, age 72, unknown 58.2
1848 Female, age 42, unknown 52.7
2849 Male, age 72, unknown 48.6
Median raphe nucleus
nTPM: 52.2
2220 Male, age 76, midline 52.2
Periaquaductal grey, anterior
nTPM: 55.9
1947 Male, age 18, unknown 58.3
2502 Female, age 75, unknown 57.5
1795 Male, age 51, unknown 52.0
Periaquaductal grey, dorsal
nTPM: 51.8
1840 Male, age 53, unknown 56.0
1831 Male, age 72, unknown 54.6
2464 Female, age 72, unknown 49.7
2850 Male, age 76, both hemispheres 46.8
Periaquaductal grey, lateral
nTPM: 49.4
2140 Male, age 76, both hemispheres 51.2
2053 Male, age 18, unknown 49.6
2272 Male, age 74, both hemispheres 47.5
Pretectal area
nTPM: 55.2
2007 Male, age 72, unknown 63.8
1944 Female, age 72, unknown 63.3
1817 Female, age 42, unknown 62.0
1816 Male, age 51, unknown 60.7
1815 Male, age 53, unknown 58.5
2667 Female, age 75, unknown 53.3
2407 Male, age 75, both hemispheres 52.1
2224 Female, age 72, unknown 51.2
2825 Male, age 18, unknown 50.3
2273 Male, age 74, both hemispheres 49.2
2316 Male, age 76, right hemisphere 42.9
Red nucleus
nTPM: 52.8
2588 Male, age 74, left hemisphere 63.9
1821 Female, age 72, unknown 59.1
2584 Male, age 75, left hemisphere 57.9
2785 Male, age 18, unknown 56.8
2769 Male, age 72, unknown 53.1
2725 Female, age 75, unknown 50.5
1865 Male, age 51, unknown 50.1
2503 Female, age 72, unknown 49.5
1954 Female, age 42, unknown 49.0
1904 Male, age 53, unknown 48.2
2227 Male, age 72, unknown 48.2
2823 Male, age 76, right hemisphere 47.6
Substantia nigra
nTPM: 65.9
1916 Female, age 42, unknown 89.5
1851 Male, age 51, unknown 76.7
2665 Male, age 74, both hemispheres 72.8
2241 Male, age 72, unknown 69.6
2699 Male, age 18, unknown 63.6
2583 Male, age 75, right hemisphere 63.3
1889 Female, age 72, unknown 62.0
2590 Female, age 75, unknown 56.6
1941 Male, age 53, unknown 56.1
2409 Female, age 72, unknown 48.7
Superior colliculus
nTPM: 53.2
2664 Male, age 75, both hemispheres 65.8
2668 Female, age 75, unknown 63.0
1796 Male, age 53, unknown 56.5
1839 Male, age 51, unknown 56.3
2087 Female, age 72, unknown 54.0
1895 Male, age 76, right hemisphere 51.0
2587 Male, age 74, left hemisphere 50.0
2261 Male, age 18, unknown 48.1
1995 Male, age 72, unknown 45.5
1913 Female, age 42, unknown 42.0
Ventral tegmental area
nTPM: 58.5
2410 Female, age 72, unknown 70.9
1915 Female, age 42, unknown 69.3
2218 Male, age 76, both hemispheres 58.2
1942 Male, age 51, unknown 53.1
2223 Female, age 72, unknown 50.6
2021 Male, age 53, unknown 49.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

55.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 55.4
Samples: 139

Max nTPM: 101.6
Min nTPM: 34.8
Std nTPM: 10.5
Median nTPM: 54.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 101.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 85.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 80.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 79.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 76.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 76.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 75.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 74.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 72.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 69.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 69.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 69.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 68.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 68.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 67.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 67.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 66.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 66.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 65.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 65.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 64.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 64.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 64.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 64.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 64.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 63.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 63.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 63.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 63.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 63.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 63.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 62.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 62.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 62.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 62.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 61.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 61.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 61.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 61.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 60.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 60.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 60.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 59.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 59.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 59.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 59.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 59.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 59.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 58.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 58.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 58.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 58.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 58.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 57.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 57.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 57.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 57.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 56.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 56.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 56.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 55.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 55.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 55.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 55.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 54.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 54.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 54.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 54.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 53.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 53.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 53.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 53.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 52.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 52.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 52.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 52.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 52.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 51.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 51.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 51.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 51.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 51.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 50.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 50.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 50.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 50.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 50.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 50.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 50.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 49.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 49.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 49.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 48.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 48.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 48.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 48.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 48.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 48.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 47.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 47.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 47.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 46.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 46.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 46.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 46.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 46.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 45.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 45.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 45.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 44.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 44.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 44.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 43.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 43.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 43.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 43.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 43.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 43.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 43.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 42.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 42.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 42.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 41.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 41.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 41.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 40.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 40.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 39.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 39.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 37.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 37.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 34.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.5
FF:10158-103A5 76 years, female 31.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 19.7
Samples: 4

Max nTPM: 21.5
Min nTPM: 17.6
Sample A Female 19.4
Sample B Female 17.6
Sample C Male 20.4
Sample D Male 21.5
Midbrain
nTPM: 21.6
Samples: 4

Max nTPM: 24.1
Min nTPM: 18.0
Sample A Female 21.8
Sample B Female 18.0
Sample C Male 24.1
Sample D Male 22.5
Periaqueductal gray
nTPM: 18.5
Samples: 3

Max nTPM: 18.7
Min nTPM: 18.4
Sample B Female 18.5
Sample C Male 18.4
Sample D Male 18.7
Superior colliculi
nTPM: 21.5
Samples: 4

Max nTPM: 25.1
Min nTPM: 18.8
Sample A Female 20.1
Sample B Female 18.8
Sample C Male 25.1
Sample D Male 22.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 60.6
Samples: 4

Max nTPM: 62.5
Min nTPM: 58.5
Sample A Male 60.7
Sample B Male 62.5
Sample C Female 58.5
Sample D Female 60.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.2
68193029 Antisense, RP_040825_01_F02, Mouse strain C57BL/6J (56 days, male) 2.2

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