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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:112.5 nTPM
HPA Brain:200.6 nTPM
GTEx:112.5 nTPM
FANTOM5:50.9 Scaled Tags Per Million
Pig:1853.2 nTPM
Mouse:17.9 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

200.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 29.7
2666 Male, age 74, left hemisphere 43.4
2019 Male, age 18, unknown 36.7
2219 Male, age 76, both hemispheres 35.5
1833 Male, age 53, unknown 34.0
1830 Male, age 51, unknown 33.9
2828 Female, age 72, unknown 32.1
2586 Male, age 75, left hemisphere 24.1
1827 Male, age 72, unknown 23.2
2411 Female, age 72, unknown 23.2
1870 Female, age 42, unknown 11.4
Dorsal raphe nucleus
nTPM: 46.2
2298 Female, age 72, unknown 116.2
1828 Male, age 53, unknown 32.8
2750 Male, age 76, both hemispheres 27.8
2016 Female, age 72, unknown 27.4
2047 Male, age 72, unknown 26.5
Inferior colliculus
nTPM: 58.8
1890 Male, age 53, unknown 99.4
2849 Male, age 72, unknown 85.4
2097 Female, age 72, unknown 27.7
1848 Female, age 42, unknown 22.6
Median raphe nucleus
nTPM: 24.1
2220 Male, age 76, midline 24.1
Periaquaductal grey, anterior
nTPM: 33.6
1795 Male, age 51, unknown 61.3
1947 Male, age 18, unknown 24.4
2502 Female, age 75, unknown 15.2
Periaquaductal grey, dorsal
nTPM: 74.1
1831 Male, age 72, unknown 129.0
2464 Female, age 72, unknown 96.4
2850 Male, age 76, both hemispheres 38.0
1840 Male, age 53, unknown 32.9
Periaquaductal grey, lateral
nTPM: 200.6
2272 Male, age 74, both hemispheres 465.0
2053 Male, age 18, unknown 106.0
2140 Male, age 76, both hemispheres 30.8
Pretectal area
nTPM: 42.3
2273 Male, age 74, both hemispheres 107.4
2667 Female, age 75, unknown 74.6
1815 Male, age 53, unknown 69.7
2316 Male, age 76, right hemisphere 35.5
2224 Female, age 72, unknown 34.0
2407 Male, age 75, both hemispheres 29.9
2825 Male, age 18, unknown 29.3
1816 Male, age 51, unknown 28.2
1944 Female, age 72, unknown 25.9
2007 Male, age 72, unknown 17.0
1817 Female, age 42, unknown 13.8
Red nucleus
nTPM: 48.4
1821 Female, age 72, unknown 129.0
2588 Male, age 74, left hemisphere 115.9
2725 Female, age 75, unknown 52.7
2785 Male, age 18, unknown 48.0
1865 Male, age 51, unknown 37.6
2769 Male, age 72, unknown 36.7
2823 Male, age 76, right hemisphere 32.8
1954 Female, age 42, unknown 29.2
1904 Male, age 53, unknown 27.6
2584 Male, age 75, left hemisphere 27.2
2227 Male, age 72, unknown 25.5
2503 Female, age 72, unknown 19.0
Substantia nigra
nTPM: 30.4
2409 Female, age 72, unknown 47.9
1889 Female, age 72, unknown 37.8
2665 Male, age 74, both hemispheres 32.4
1941 Male, age 53, unknown 29.4
2699 Male, age 18, unknown 29.4
1851 Male, age 51, unknown 28.7
2241 Male, age 72, unknown 28.3
2583 Male, age 75, right hemisphere 25.9
1916 Female, age 42, unknown 24.4
2590 Female, age 75, unknown 19.7
Superior colliculus
nTPM: 61.4
2587 Male, age 74, left hemisphere 263.2
1995 Male, age 72, unknown 78.2
2261 Male, age 18, unknown 44.9
2668 Female, age 75, unknown 44.6
2087 Female, age 72, unknown 36.1
1895 Male, age 76, right hemisphere 34.1
1839 Male, age 51, unknown 30.9
1796 Male, age 53, unknown 27.5
2664 Male, age 75, both hemispheres 27.3
1913 Female, age 42, unknown 26.9
Ventral tegmental area
nTPM: 35.8
1915 Female, age 42, unknown 54.6
2223 Female, age 72, unknown 50.5
2021 Male, age 53, unknown 35.7
2218 Male, age 76, both hemispheres 31.5
1942 Male, age 51, unknown 25.8
2410 Female, age 72, unknown 16.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

112.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 112.5
Samples: 139

Max nTPM: 1436.4
Min nTPM: 0.2
Std nTPM: 243.6
Median nTPM: 22.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1436.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1166.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1061.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1028.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 805.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 798.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 774.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 703.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 637.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 616.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 511.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 402.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 355.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 320.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 292.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 231.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 209.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 198.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 194.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 162.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 157.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 150.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 149.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 149.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 125.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 124.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 118.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 113.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 112.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 110.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 110.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 98.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 94.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 93.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 92.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 86.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 79.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 73.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 71.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 69.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 55.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 51.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 50.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 44.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 42.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 41.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 39.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 39.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 37.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 36.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 35.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 35.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 35.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 34.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 34.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 33.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 31.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 31.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 30.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 28.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 28.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 26.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 26.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 24.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 24.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 23.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 22.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 22.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 22.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 22.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 22.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 21.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 21.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 19.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 17.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 17.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 17.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 16.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 16.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 15.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 15.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 15.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 15.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 14.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 12.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 11.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 10.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 10.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 10.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 10.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 10.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 9.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 9.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 9.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 9.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 8.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 7.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 7.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 7.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 7.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 7.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 6.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 5.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 5.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 5.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 5.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 4.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 4.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 4.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 4.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 3.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 3.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 3.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 3.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 2.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 2.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 2.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 2.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 2.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 2.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 0.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 0.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 0.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 0.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 0.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

50.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 50.9
FF:10158-103A5 76 years, female 50.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1853.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 243.4
Samples: 4

Max nTPM: 474.7
Min nTPM: 131.3
Sample A Female 215.5
Sample B Female 474.7
Sample C Male 131.3
Sample D Male 152.2
Midbrain
nTPM: 144.1
Samples: 4

Max nTPM: 318.7
Min nTPM: 48.9
Sample A Female 116.6
Sample B Female 318.7
Sample C Male 92.1
Sample D Male 48.9
Periaqueductal gray
nTPM: 96.9
Samples: 3

Max nTPM: 177.8
Min nTPM: 9.0
Sample B Female 177.8
Sample C Male 9.0
Sample D Male 103.9
Superior colliculi
nTPM: 1853.2
Samples: 4

Max nTPM: 7220.8
Min nTPM: 15.0
Sample A Female 85.3
Sample B Female 7220.8
Sample C Male 15.0
Sample D Male 91.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

17.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 17.9
Samples: 4

Max nTPM: 50.5
Min nTPM: 1.7
Sample A Male 50.5
Sample B Male 1.7
Sample C Female 12.5
Sample D Female 6.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
68632172 Antisense, RP_050125_01_G11, Mouse strain C57BL/6J (56 days, male) 0.1

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