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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:97.7 nTPM
HPA Brain:95.4 nTPM
GTEx:97.7 nTPM
FANTOM5:23.2 Scaled Tags Per Million
Pig:166.4 nTPM
Mouse:109.3 nTPM
Allen mouse:2.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 85.2
2411 Female, age 72, unknown 101.6
1870 Female, age 42, unknown 96.5
2019 Male, age 18, unknown 90.9
1833 Male, age 53, unknown 89.6
1827 Male, age 72, unknown 85.5
1830 Male, age 51, unknown 83.0
2219 Male, age 76, both hemispheres 82.7
2828 Female, age 72, unknown 76.6
2666 Male, age 74, left hemisphere 76.3
2586 Male, age 75, left hemisphere 69.7
Dorsal raphe nucleus
nTPM: 95.4
2298 Female, age 72, unknown 104.3
1828 Male, age 53, unknown 102.9
2047 Male, age 72, unknown 92.3
2016 Female, age 72, unknown 90.8
2750 Male, age 76, both hemispheres 86.7
Inferior colliculus
nTPM: 88.5
2097 Female, age 72, unknown 95.6
1890 Male, age 53, unknown 91.2
1848 Female, age 42, unknown 86.9
2849 Male, age 72, unknown 80.5
Median raphe nucleus
nTPM: 91.4
2220 Male, age 76, midline 91.4
Periaquaductal grey, anterior
nTPM: 81.3
1947 Male, age 18, unknown 84.9
2502 Female, age 75, unknown 80.9
1795 Male, age 51, unknown 78.0
Periaquaductal grey, dorsal
nTPM: 85.9
2850 Male, age 76, both hemispheres 102.2
1840 Male, age 53, unknown 84.0
2464 Female, age 72, unknown 80.2
1831 Male, age 72, unknown 77.0
Periaquaductal grey, lateral
nTPM: 81.1
2140 Male, age 76, both hemispheres 82.4
2053 Male, age 18, unknown 82.1
2272 Male, age 74, both hemispheres 78.9
Pretectal area
nTPM: 84.1
2224 Female, age 72, unknown 93.9
1817 Female, age 42, unknown 92.6
1815 Male, age 53, unknown 90.7
1816 Male, age 51, unknown 90.6
2273 Male, age 74, both hemispheres 90.1
2667 Female, age 75, unknown 88.9
2007 Male, age 72, unknown 83.9
2825 Male, age 18, unknown 81.2
2316 Male, age 76, right hemisphere 79.6
1944 Female, age 72, unknown 76.8
2407 Male, age 75, both hemispheres 57.4
Red nucleus
nTPM: 89.3
1821 Female, age 72, unknown 122.4
2725 Female, age 75, unknown 99.5
1954 Female, age 42, unknown 94.9
2823 Male, age 76, right hemisphere 93.6
1904 Male, age 53, unknown 92.9
1865 Male, age 51, unknown 92.2
2503 Female, age 72, unknown 90.7
2769 Male, age 72, unknown 90.2
2227 Male, age 72, unknown 88.2
2785 Male, age 18, unknown 83.7
2588 Male, age 74, left hemisphere 66.3
2584 Male, age 75, left hemisphere 57.4
Substantia nigra
nTPM: 93.5
1916 Female, age 42, unknown 112.8
1851 Male, age 51, unknown 104.3
2409 Female, age 72, unknown 102.2
2241 Male, age 72, unknown 99.0
2699 Male, age 18, unknown 95.1
1889 Female, age 72, unknown 91.1
2665 Male, age 74, both hemispheres 89.2
1941 Male, age 53, unknown 84.3
2590 Female, age 75, unknown 81.7
2583 Male, age 75, right hemisphere 75.4
Superior colliculus
nTPM: 81.7
1895 Male, age 76, right hemisphere 95.4
1913 Female, age 42, unknown 95.2
2587 Male, age 74, left hemisphere 94.2
1995 Male, age 72, unknown 91.3
2668 Female, age 75, unknown 76.5
1796 Male, age 53, unknown 76.3
2087 Female, age 72, unknown 76.2
1839 Male, age 51, unknown 75.8
2261 Male, age 18, unknown 75.2
2664 Male, age 75, both hemispheres 60.5
Ventral tegmental area
nTPM: 92.2
2410 Female, age 72, unknown 104.3
2218 Male, age 76, both hemispheres 97.2
1915 Female, age 42, unknown 96.0
2223 Female, age 72, unknown 93.8
1942 Male, age 51, unknown 81.5
2021 Male, age 53, unknown 80.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

97.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 97.7
Samples: 139

Max nTPM: 169.8
Min nTPM: 56.0
Std nTPM: 18.3
Median nTPM: 97.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 169.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 143.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 141.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 137.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 135.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 131.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 130.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 128.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 127.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 126.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 125.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 122.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 121.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 119.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 118.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 117.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 117.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 117.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 116.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 116.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 116.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 115.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 114.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 113.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 112.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 112.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 112.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 111.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 111.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 108.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 108.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 108.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 107.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 107.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 107.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 107.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 107.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 107.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 106.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 105.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 105.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 105.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 104.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 104.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 104.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 103.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 103.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 103.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 103.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 103.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 103.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 103.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 103.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 103.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 102.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 102.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 102.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 102.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 102.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 102.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 102.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 101.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 100.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 99.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 99.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 99.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 98.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 98.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 98.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 97.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 97.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 96.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 96.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 95.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 95.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 95.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 95.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 95.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 94.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 94.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 94.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 93.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 93.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 93.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 92.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 92.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 92.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 92.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 91.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 90.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 90.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 90.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 88.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 87.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 87.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 87.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 87.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 86.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 86.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 86.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 86.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 86.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 85.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 85.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 85.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 84.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 84.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 83.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 82.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 82.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 81.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 81.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 80.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 80.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 80.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 79.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 78.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 75.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 75.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 75.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 74.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 74.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 74.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 74.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 73.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 73.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 72.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 70.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 69.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 69.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 67.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 67.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 67.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 62.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 56.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

23.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 23.2
FF:10158-103A5 76 years, female 23.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

166.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 166.4
Samples: 4

Max nTPM: 207.6
Min nTPM: 145.0
Sample A Female 207.6
Sample B Female 145.7
Sample C Male 167.3
Sample D Male 145.0
Midbrain
nTPM: 161.5
Samples: 4

Max nTPM: 218.3
Min nTPM: 119.2
Sample A Female 218.3
Sample B Female 173.8
Sample C Male 119.2
Sample D Male 134.5
Periaqueductal gray
nTPM: 150.6
Samples: 3

Max nTPM: 156.6
Min nTPM: 143.8
Sample B Female 151.5
Sample C Male 156.6
Sample D Male 143.8
Superior colliculi
nTPM: 150.8
Samples: 4

Max nTPM: 175.2
Min nTPM: 135.3
Sample A Female 175.2
Sample B Female 135.3
Sample C Male 142.5
Sample D Male 150.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 109.3
Samples: 4

Max nTPM: 113.5
Min nTPM: 105.4
Sample A Male 107.4
Sample B Male 105.4
Sample C Female 111.0
Sample D Female 113.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.8
68667312 Antisense, RP_050201_02_A06, Mouse strain C57BL/6J (56 days, male) 2.8

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