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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
80.4
nTPM
HPA:
80.4
nTPM
GTEx:
71.5
nTPM
FANTOM5:
169.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA031075
Antibody CAB005123
Cholangiocytes
Low
-
Hepatocytes
Low
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
80.4
Female, age 60
Liver sample 21 nTPM: 93.5
Male, age 54
Liver sample 23 nTPM: 61.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 227.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 68.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 157.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 34.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 40.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 48.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 23.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 48
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
71.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 71.5
Samples: 226
Max nTPM: 327.8
Min nTPM: 3.3
Std nTPM: 66.5
Median nTPM: 47.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
327.8
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
315.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
302.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
293.4
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
273.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
240.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
231.6
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
213.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
211.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
209.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
209.0
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
207.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
204.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
202.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
201.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
199.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
198.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
193.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
193.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
188.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
188.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
175.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
175.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
173.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
170.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
166.6
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
163.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
161.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
156.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
149.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
145.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
145.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
140.0
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
138.4
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
136.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
134.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
134.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
131.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
131.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
129.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
127.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
125.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
123.7
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
119.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
119.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
117.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
116.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
114.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
114.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
110.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
108.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
108.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
107.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
107.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
106.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
101.2
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
100.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
99.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
97.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
94.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
91.7
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
91.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
91.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
90.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
89.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
88.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
86.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
86.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
84.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
82.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
82.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
81.3
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
79.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
78.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
77.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
75.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
75.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
74.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
74.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
73.2
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
72.7
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
72.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
70.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
68.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
67.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
67.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
66.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
66.5
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
64.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
63.0
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
62.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
62.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
61.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
61.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
60.5
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
60.3
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
60.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
58.7
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
58.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
58.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
57.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
57.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
56.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
56.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
55.5
GTEX-1B933-1226-SM-731DW
50-59 years, female
55.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
54.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
54.0
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
53.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
52.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
49.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
48.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
48.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
46.2
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
44.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
44.6
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
44.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
43.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
41.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
41.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
41.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
40.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
39.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
39.6
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
38.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
36.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
36.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
36.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
36.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
35.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
35.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
35.0
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
35.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
34.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
34.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
34.3
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
33.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
32.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
32.6
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
32.5
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
32.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
32.0
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
31.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
31.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
31.5
GTEX-1B932-1426-SM-793AN
40-49 years, female
30.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
30.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
30.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
30.2
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
30.1
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
29.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
28.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
28.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
28.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
28.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
27.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
27.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
27.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
27.3
GTEX-14PHX-0526-SM-664NW
50-59 years, male
26.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
26.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
26.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
25.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
24.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
24.4
GTEX-RU72-1426-SM-46MUF
50-59 years, female
24.3
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
24.1
GTEX-14XAO-0226-SM-68728
60-69 years, female
24.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
24.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
24.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
23.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
23.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
23.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
23.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
23.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
22.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
22.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
21.8
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
20.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
20.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
20.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
19.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
18.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
18.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
17.7
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
17.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
17.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
16.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
16.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
16.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
15.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
15.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
14.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
14.1
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
13.8
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
13.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
13.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
13.5
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
13.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
13.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
13.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
12.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
11.7
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
11.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
11.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
10.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
10.9
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
10.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
10.4
GTEX-O5YV-0726-SM-EV798
60-69 years, female
9.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
9.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
9.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
9.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
8.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
7.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
7.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
7.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
7.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
6.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
6.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
6.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
5.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
4.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
4.6
GTEX-REY6-1226-SM-48FDR
60-69 years, male
3.5
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
3.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
